| Small molecule mitochondrial uncouplers and their therapeutic potential: miniperspective ES Childress, SJ Alexopoulos, KL Hoehn, WL Santos Journal of Medicinal Chemistry 61 (11), 4641-4655, 2017 | 134 | 2017 |
| Mitochondrial uncoupler BAM15 reverses diet-induced obesity and insulin resistance in mice SJ Alexopoulos, SY Chen, AE Brandon, JM Salamoun, FL Byrne, ... Nature Communications 11 (1), 2397, 2020 | 82 | 2020 |
| Cholesterol homeostasis: How do cells sense sterol excess? V Howe, LJ Sharpe, SJ Alexopoulos, SV Kunze, NK Chua, D Li, AJ Brown Chemistry and physics of lipids 199, 170-178, 2016 | 77 | 2016 |
| BAM15‐mediated mitochondrial uncoupling protects against obesity and improves glycemic control CL Axelrod, WT King, G Davuluri, RC Noland, J Hall, M Hull, WS Dantas, ... EMBO Molecular Medicine 12 (7), e12088, 2020 | 57 | 2020 |
| Eosinophil function in adipose tissue is regulated by Krüppel-like factor 3 (KLF3) AJ Knights, EJ Vohralik, PJ Houweling, ES Stout, LJ Norton, ... Nature Communications 11 (1), 2922, 2020 | 40 | 2020 |
| UGCG overexpression leads to increased glycolysis and increased oxidative phosphorylation of breast cancer cells N Schömel, L Gruber, SJ Alexopoulos, S Trautmann, EM Olzomer, ... Scientific reports 10 (1), 8182, 2020 | 40 | 2020 |
| [1,2,5]Oxadiazolo[3,4-b]pyrazine-5,6-diamine Derivatives as Mitochondrial Uncouplers for the Potential Treatment of Nonalcoholic Steatohepatitis ES Childress, JM Salamoun, SR Hargett, SJ Alexopoulos, SY Chen, ... Journal of medicinal chemistry 63 (5), 2511-2526, 2020 | 31 | 2020 |
| 6-Amino[1,2,5]oxadiazolo[3,4-b]pyrazin-5-ol Derivatives as Efficacious Mitochondrial Uncouplers in STAM Mouse Model of Nonalcoholic Steatohepatitis JM Salamoun, CJ Garcia, SR Hargett, JH Murray, SY Chen, M Beretta, ... Journal of medicinal chemistry 63 (11), 6203-6224, 2020 | 20 | 2020 |
| Breast cancer growth and proliferation is suppressed by the mitochondrial targeted furazano [3, 4-b] pyrazine BAM15 ERM Zunica, CL Axelrod, E Cho, G Spielmann, G Davuluri, ... Cancer & Metabolism 9, 1-20, 2021 | 17 | 2021 |
| Mitochondrial uncoupler SHC517 reverses obesity in mice without affecting food intake SY Chen, M Beretta, SJ Alexopoulos, DP Shah, EM Olzomer, SR Hargett, ... Metabolism 117, 154724, 2021 | 13 | 2021 |
| Phenotypic screen for oxygen consumption rate identifies an anti-cancer naphthoquinone that induces mitochondrial oxidative stress FL Byrne, EM Olzomer, GR Marriott, LE Quek, A Katen, J Su, ME Nelson, ... Redox biology 28, 101374, 2020 | 13 | 2020 |
| Targeting negative energy balance with calorie restriction and mitochondrial uncoupling in db/db mice SY Chen, M Beretta, EM Olzomer, DP Shah, DYH Wong, SJ Alexopoulos, ... Molecular metabolism 69, 101684, 2023 | 5 | 2023 |
| Liver-selective imidazolopyrazine mitochondrial uncoupler SHD865 reverses adiposity and glucose intolerance in mice M Beretta, Y Dai, EM Olzomer, CS Vancuylenburg, JA Santiago-Rivera, ... Diabetes 73 (3), 374-384, 2024 | 3 | 2024 |
| Beneficial effects of simultaneously targeting calorie intake and calorie efficiency in diet-induced obese mice SY Chen, AJ Telfser, EM Olzomer, CS Vancuylenberg, M Zhou, M Beretta, ... Clinical Science 138 (4), 173-187, 2024 | | 2024 |
| Head-to-head comparison of BAM15, semaglutide, rosiglitazone, NEN, and calorie restriction on metabolic physiology in female db/db mice SY Chen, M Beretta, EM Olzomer, SJ Alexopoulos, DP Shah, FL Byrne, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1870 (1), 166908, 2024 | | 2024 |
| Assessing the therapeutic potential of mitochondrial uncoupler BAM15 S Alexopoulos UNSW Sydney, 2023 | | 2023 |
| Mitochondrial Uncoupler BAM15 Ameliorates Associated Metabolic PCOS Traits in a Hyperandrogenic PCOS Mouse Model V RODRIGUEZ PARIS, SJ ALEXOPOULOS, Y HU, DP SHAH, ... Fertility & Reproduction 4 (03n04), 208-208, 2022 | | 2022 |
| Metabolic PCOS Features Are Ameliorated by Mitochondrial Uncoupler BAM15 in a PCOS Mouse Model VR Paris, SJ Alexopoulos, Y Hu, DP Shah, A Aflatounian, MC Edwards, ... Journal of the Endocrine Society 5 (Suppl 1), A769, 2021 | | 2021 |
| Antitumor Effects of BAM15 in Obese Mice With Triple Negative Breast Cancer E Zunica, C Axelrod, W King, G Spielmann, B Irving, S Alexopoulos, ... OBESITY 28, 7-7, 2020 | | 2020 |
| [1, 2, 5] Oxadiazolo [3, 4-b] pyrazine-5, 6-diamine Derivatives as Mitochondrial Uncouplers for the Potential Treatment of Nonalcoholic Steatohepatitis B Azal, M Machacek, MA Shalaby, V Novakova, P Zimcik, S Makhseed, ... Journal of Medicinal Chemistry 63, 2511-2526, 2020 | | 2020 |
