Visualizing engrafted human cancer and therapy responses in immunodeficient zebrafish C Yan, DC Brunson, Q Tang, D Do, NA Iftimia, JC Moore, MN Hayes, ... Cell 177 (7), 1903-1914. e14, 2019 | 231 | 2019 |
Zebrafish patient avatars in cancer biology and precision cancer therapy M Fazio, J Ablain, Y Chuan, DM Langenau, LI Zon Nature Reviews Cancer 20 (5), 263-273, 2020 | 173 | 2020 |
Toxicogenomic and phenotypic analyses of bisphenol-A early-life exposure toxicity in zebrafish SH Lam, MM Hlaing, X Zhang, C Yan, Z Duan, L Zhu, CY Ung, ... PloS one 6 (12), e28273, 2011 | 161 | 2011 |
A transgenic zebrafish liver tumor model with inducible Myc expression reveals conserved Myc signatures with mammalian liver tumors Z Li, W Zheng, Z Wang, Z Zeng, H Zhan, C Li, L Zhou, C Yan, ... Disease models & mechanisms 6 (2), 414-423, 2013 | 83 | 2013 |
Stimulation of hepatocarcinogenesis by neutrophils upon induction of oncogenic kras expression in transgenic zebrafish C Yan, X Huo, S Wang, Y Feng, Z Gong Journal of hepatology 63 (2), 420-428, 2015 | 77 | 2015 |
Tumor-associated neutrophils and macrophages promote gender disparity in hepatocellular carcinoma in zebrafish C Yan, Q Yang, Z Gong Cancer research 77 (6), 1395-1407, 2017 | 65 | 2017 |
Transcriptomic profiles of tumor-associated neutrophils reveal prominent roles in enhancing angiogenesis in liver tumorigenesis in zebrafish X Huo, H Li, Z Li, C Yan, I Agrawal, S Mathavan, J Liu, Z Gong Scientific reports 9 (1), 1509, 2019 | 38 | 2019 |
Serotonin activated hepatic stellate cells contribute to sex disparity in hepatocellular carcinoma Q Yang, C Yan, C Yin, Z Gong Cellular and Molecular Gastroenterology and Hepatology 3 (3), 484-499, 2017 | 34 | 2017 |
Leptin induces muscle wasting in a zebrafish kras-driven hepatocellular carcinoma (HCC) model Q Yang, C Yan, X Wang, Z Gong Disease models & mechanisms 12 (2), dmm038240, 2019 | 31 | 2019 |
Chronically high level of tgfb1a induction causes both hepatocellular carcinoma and cholangiocarcinoma via a dominant Erk pathway in zebrafish C Yan, Q Yang, HM Shen, JM Spitsbergen, Z Gong Oncotarget 8 (44), 77096, 2017 | 30 | 2017 |
Interaction of hepatic stellate cells with neutrophils and macrophages in the liver following oncogenic kras activation in transgenic zebrafish Q Yang, C Yan, Z Gong Scientific Reports 8 (1), 8495, 2018 | 28 | 2018 |
Single-cell analysis and functional characterization uncover the stem cell hierarchies and developmental origins of rhabdomyosarcoma Y Wei, Q Qin, C Yan, MN Hayes, SP Garcia, H Xi, D Do, AH Jin, TC Eng, ... Nature cancer 3 (8), 961-975, 2022 | 26 | 2022 |
Adult immune compromised zebrafish for xenograft cell transplantation studies C Yan, Q Yang, D Do, DC Brunson, DM Langenau EBioMedicine 47, 24-26, 2019 | 24 | 2019 |
Rapid analysis of effects of environmental toxicants on tumorigenesis and inflammation using a transgenic zebrafish model for liver cancer Q Yang, L Salim, C Yan, Z Gong Marine Biotechnology 21, 396-405, 2019 | 24 | 2019 |
Therapeutic targeting of LCK tyrosine kinase and mTOR signaling in T-cell acute lymphoblastic leukemia S Laukkanen, A Veloso, C Yan, L Oksa, EJ Alpert, D Do, N Hyvärinen, ... Blood, The Journal of the American Society of Hematology 140 (17), 1891-1906, 2022 | 23 | 2022 |
Activation of hepatic stellate cells during liver carcinogenesis requires fibrinogen/integrin αvβ5 in zebrafish C Yan, Q Yang, Z Gong Neoplasia 20 (5), 533-542, 2018 | 23 | 2018 |
Directed differentiation of human embryonic stem cells to neural crest stem cells, functional peripheral neurons, and corneal keratocytes Q Zhu, M Li, C Yan, Q Lu, S Wei, R Gao, M Yu, Y Zou, G Sriram, HJ Tong, ... Biotechnology journal 12 (12), 1700067, 2017 | 23 | 2017 |
Single-cell imaging of human cancer xenografts using adult immunodeficient zebrafish C Yan, D Do, Q Yang, DC Brunson, JF Rawls, DM Langenau Nature protocols 15 (9), 3105-3128, 2020 | 22 | 2020 |
Transcriptomic analysis of a transgenic zebrafish hepatocellular carcinoma model reveals a prominent role of immune responses in tumour progression and regression Z Li, H Luo, C Li, X Huo, C Yan, X Huang, M Al‐Haddawi, S Mathavan, ... International journal of cancer 135 (7), 1564-1573, 2014 | 21 | 2014 |
PRL3 enhances T-cell acute lymphoblastic leukemia growth through suppressing T-cell signaling pathways and apoptosis EG Garcia, A Veloso, ML Oliveira, JR Allen, S Loontiens, D Brunson, D Do, ... Leukemia 35 (3), 679-690, 2021 | 19 | 2021 |