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Chuan Yan
Chuan Yan
Department of Pathology, Massachusetts General Hospital
在 mgh.harvard.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Visualizing engrafted human cancer and therapy responses in immunodeficient zebrafish
C Yan, DC Brunson, Q Tang, D Do, NA Iftimia, JC Moore, MN Hayes, ...
Cell 177 (7), 1903-1914. e14, 2019
2312019
Zebrafish patient avatars in cancer biology and precision cancer therapy
M Fazio, J Ablain, Y Chuan, DM Langenau, LI Zon
Nature Reviews Cancer 20 (5), 263-273, 2020
1732020
Toxicogenomic and phenotypic analyses of bisphenol-A early-life exposure toxicity in zebrafish
SH Lam, MM Hlaing, X Zhang, C Yan, Z Duan, L Zhu, CY Ung, ...
PloS one 6 (12), e28273, 2011
1612011
A transgenic zebrafish liver tumor model with inducible Myc expression reveals conserved Myc signatures with mammalian liver tumors
Z Li, W Zheng, Z Wang, Z Zeng, H Zhan, C Li, L Zhou, C Yan, ...
Disease models & mechanisms 6 (2), 414-423, 2013
832013
Stimulation of hepatocarcinogenesis by neutrophils upon induction of oncogenic kras expression in transgenic zebrafish
C Yan, X Huo, S Wang, Y Feng, Z Gong
Journal of hepatology 63 (2), 420-428, 2015
772015
Tumor-associated neutrophils and macrophages promote gender disparity in hepatocellular carcinoma in zebrafish
C Yan, Q Yang, Z Gong
Cancer research 77 (6), 1395-1407, 2017
652017
Transcriptomic profiles of tumor-associated neutrophils reveal prominent roles in enhancing angiogenesis in liver tumorigenesis in zebrafish
X Huo, H Li, Z Li, C Yan, I Agrawal, S Mathavan, J Liu, Z Gong
Scientific reports 9 (1), 1509, 2019
382019
Serotonin activated hepatic stellate cells contribute to sex disparity in hepatocellular carcinoma
Q Yang, C Yan, C Yin, Z Gong
Cellular and Molecular Gastroenterology and Hepatology 3 (3), 484-499, 2017
342017
Leptin induces muscle wasting in a zebrafish kras-driven hepatocellular carcinoma (HCC) model
Q Yang, C Yan, X Wang, Z Gong
Disease models & mechanisms 12 (2), dmm038240, 2019
312019
Chronically high level of tgfb1a induction causes both hepatocellular carcinoma and cholangiocarcinoma via a dominant Erk pathway in zebrafish
C Yan, Q Yang, HM Shen, JM Spitsbergen, Z Gong
Oncotarget 8 (44), 77096, 2017
302017
Interaction of hepatic stellate cells with neutrophils and macrophages in the liver following oncogenic kras activation in transgenic zebrafish
Q Yang, C Yan, Z Gong
Scientific Reports 8 (1), 8495, 2018
282018
Single-cell analysis and functional characterization uncover the stem cell hierarchies and developmental origins of rhabdomyosarcoma
Y Wei, Q Qin, C Yan, MN Hayes, SP Garcia, H Xi, D Do, AH Jin, TC Eng, ...
Nature cancer 3 (8), 961-975, 2022
262022
Adult immune compromised zebrafish for xenograft cell transplantation studies
C Yan, Q Yang, D Do, DC Brunson, DM Langenau
EBioMedicine 47, 24-26, 2019
242019
Rapid analysis of effects of environmental toxicants on tumorigenesis and inflammation using a transgenic zebrafish model for liver cancer
Q Yang, L Salim, C Yan, Z Gong
Marine Biotechnology 21, 396-405, 2019
242019
Therapeutic targeting of LCK tyrosine kinase and mTOR signaling in T-cell acute lymphoblastic leukemia
S Laukkanen, A Veloso, C Yan, L Oksa, EJ Alpert, D Do, N Hyvärinen, ...
Blood, The Journal of the American Society of Hematology 140 (17), 1891-1906, 2022
232022
Activation of hepatic stellate cells during liver carcinogenesis requires fibrinogen/integrin αvβ5 in zebrafish
C Yan, Q Yang, Z Gong
Neoplasia 20 (5), 533-542, 2018
232018
Directed differentiation of human embryonic stem cells to neural crest stem cells, functional peripheral neurons, and corneal keratocytes
Q Zhu, M Li, C Yan, Q Lu, S Wei, R Gao, M Yu, Y Zou, G Sriram, HJ Tong, ...
Biotechnology journal 12 (12), 1700067, 2017
232017
Single-cell imaging of human cancer xenografts using adult immunodeficient zebrafish
C Yan, D Do, Q Yang, DC Brunson, JF Rawls, DM Langenau
Nature protocols 15 (9), 3105-3128, 2020
222020
Transcriptomic analysis of a transgenic zebrafish hepatocellular carcinoma model reveals a prominent role of immune responses in tumour progression and regression
Z Li, H Luo, C Li, X Huo, C Yan, X Huang, M Al‐Haddawi, S Mathavan, ...
International journal of cancer 135 (7), 1564-1573, 2014
212014
PRL3 enhances T-cell acute lymphoblastic leukemia growth through suppressing T-cell signaling pathways and apoptosis
EG Garcia, A Veloso, ML Oliveira, JR Allen, S Loontiens, D Brunson, D Do, ...
Leukemia 35 (3), 679-690, 2021
192021
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