Sirtuins as regulators of metabolism and healthspan RH Houtkooper, E Pirinen, J Auwerx Nature reviews Molecular cell biology 13 (4), 225-238, 2012 | 2082 | 2012 |
Calorie restriction-like effects of 30 days of resveratrol supplementation on energy metabolism and metabolic profile in obese humans S Timmers, E Konings, L Bilet, RH Houtkooper, T van de Weijer, ... Cell metabolism 14 (5), 612-622, 2011 | 1422 | 2011 |
The NAD+ precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet-induced obesity C Cantó, RH Houtkooper, E Pirinen, DY Youn, MH Oosterveer, Y Cen, ... Cell metabolism 15 (6), 838-847, 2012 | 1267 | 2012 |
The NAD+/sirtuin pathway modulates longevity through activation of mitochondrial UPR and FOXO signaling L Mouchiroud, RH Houtkooper, N Moullan, E Katsyuba, D Ryu, C Cantó, ... Cell 154 (2), 430-441, 2013 | 1193 | 2013 |
Mitonuclear protein imbalance as a conserved longevity mechanism RH Houtkooper, L Mouchiroud, D Ryu, N Moullan, E Katsyuba, G Knott, ... Nature 497 (7450), 451-457, 2013 | 1037 | 2013 |
The Secret Life of NAD+: An Old Metabolite Controlling New Metabolic Signaling Pathways RH Houtkooper, C Cantó, RJ Wanders, J Auwerx Endocrine reviews 31 (2), 194-223, 2010 | 1001 | 2010 |
PARP-1 inhibition increases mitochondrial metabolism through SIRT1 activation P Bai, C Cantó, H Oudart, A Brunyánszki, Y Cen, C Thomas, H Yamamoto, ... Cell metabolism 13 (4), 461-468, 2011 | 875 | 2011 |
The metabolic footprint of aging in mice RH Houtkooper, C Argmann, SM Houten, C Cantó, EH Jeninga, ... Scientific reports 1 (1), 134, 2011 | 538 | 2011 |
Metabolic flexibility as an adaptation to energy resources and requirements in health and disease RL Smith, MR Soeters, RCI Wüst, RH Houtkooper Endocrine reviews 39 (4), 489-517, 2018 | 528 | 2018 |
Cardiolipin, the heart of mitochondrial metabolism RH Houtkooper, FM Vaz Cellular and Molecular Life Sciences 65, 2493-2506, 2008 | 508 | 2008 |
Tetracyclines disturb mitochondrial function across eukaryotic models: a call for caution in biomedical research N Moullan, L Mouchiroud, X Wang, D Ryu, EG Williams, A Mottis, ... Cell reports 10 (10), 1681-1691, 2015 | 492 | 2015 |
Imp2 controls oxidative phosphorylation and is crucial for preserving glioblastoma cancer stem cells M Janiszewska, ML Suvà, N Riggi, RH Houtkooper, J Auwerx, ... Genes & development 26 (17), 1926-1944, 2012 | 454 | 2012 |
Pharmacological approaches to restore mitochondrial function PA Andreux, RH Houtkooper, J Auwerx Nature reviews Drug discovery 12 (6), 465-483, 2013 | 404 | 2013 |
Cardiolipin provides an essential activating platform for caspase-8 on mitochondria F Gonzalvez, ZT Schug, RH Houtkooper, ED MacKenzie, DG Brooks, ... The Journal of cell biology 183 (4), 681-696, 2008 | 320 | 2008 |
Cardiac and skeletal muscle defects in a mouse model of human Barth syndrome D Acehan, F Vaz, RH Houtkooper, J James, V Moore, C Tokunaga, ... Journal of biological chemistry 286 (2), 899-908, 2011 | 293 | 2011 |
Laminar shear stress inhibits endothelial cell metabolism via KLF2-mediated repression of PFKFB3 A Doddaballapur, KM Michalik, Y Manavski, T Lucas, RH Houtkooper, ... Arteriosclerosis, thrombosis, and vascular biology 35 (1), 137-145, 2015 | 291 | 2015 |
Microbial stimulation of different Toll-like receptor signalling pathways induces diverse metabolic programmes in human monocytes E Lachmandas, L Boutens, JM Ratter, A Hijmans, GJ Hooiveld, ... Nature microbiology 2 (3), 1-10, 2016 | 283 | 2016 |
Disorders of mitochondrial long-chain fatty acid oxidation and the carnitine shuttle SJG Knottnerus, JC Bleeker, RCI Wüst, S Ferdinandusse, L IJlst, ... Reviews in Endocrine and Metabolic Disorders 19, 93-106, 2018 | 281 | 2018 |
Mutations in LPIN1 cause recurrent acute myoglobinuria in childhood A Zeharia, A Shaag, RH Houtkooper, T Hindi, P de Lonlay, G Erez, ... The American Journal of Human Genetics 83 (4), 489-494, 2008 | 258 | 2008 |
Metabolic networks of longevity RH Houtkooper, RW Williams, J Auwerx Cell 142 (1), 9-14, 2010 | 248 | 2010 |