| Autophagy, metabolism, and cancer E White, JM Mehnert, CS Chan Clinical cancer research 21 (22), 5037-5046, 2015 | 689 | 2015 |
| Why are there hotspot mutations in the TP53 gene in human cancers? EH Baugh, H Ke, AJ Levine, RA Bonneau, CS Chan Cell Death & Differentiation 25 (1), 154-160, 2018 | 550 | 2018 |
| Autophagy is required for glucose homeostasis and lung tumor maintenance G Karsli-Uzunbas, JY Guo, S Price, X Teng, SV Laddha, S Khor, ... Cancer discovery 4 (8), 914-927, 2014 | 541 | 2014 |
| Negative regulation of tumor suppressor p53 by microRNA miR-504 W Hu, CS Chan, R Wu, C Zhang, Y Sun, JS Song, LH Tang, AJ Levine, ... Molecular cell 38 (5), 689-699, 2010 | 367 | 2010 |
| Autophagy provides metabolic substrates to maintain energy charge and nucleotide pools in Ras-driven lung cancer cells JY Guo, X Teng, SV Laddha, S Ma, SC Van Nostrand, Y Yang, S Khor, ... Genes & development 30 (15), 1704-1717, 2016 | 361 | 2016 |
| Mutational Landscape of the Essential Autophagy Gene BECN1 in Human Cancers SV Laddha, S Ganesan, CS Chan, E White Molecular cancer research 12 (4), 485-490, 2014 | 227 | 2014 |
| ATRX, DAXX or MEN1 mutant pancreatic neuroendocrine tumors are a distinct alpha-cell signature subgroup CS Chan, SV Laddha, PW Lewis, MS Koletsky, K Robzyk, E Da Silva, ... Nature communications 9 (1), 4158, 2018 | 183 | 2018 |
| A note on warped string compactification CS Chan, PL Paul, H Verlinde Nuclear Physics B 581 (1-2), 156-164, 2000 | 152 | 2000 |
| The genomic landscape of renal oncocytoma identifies a metabolic barrier to tumorigenesis S Joshi, D Tolkunov, H Aviv, AA Hakimi, M Yao, JJ Hsieh, S Ganesan, ... Cell reports 13 (9), 1895-1908, 2015 | 151 | 2015 |
| Revealing posttranscriptional regulatory elements through network-level conservation CS Chan, O Elemento, S Tavazoie PLoS computational biology 1 (7), e69, 2005 | 110 | 2005 |
| Tumor suppressor p53 negatively regulates glycolysis stimulated by hypoxia through its target RRAD C Zhang, J Liu, R Wu, Y Liang, M Lin, J Liu, CS Chan, W Hu, Z Feng Oncotarget 5 (14), 5535, 2014 | 105 | 2014 |
| Clinical actionability of comprehensive genomic profiling for management of rare or refractory cancers KM Hirshfield, D Tolkunov, H Zhong, SM Ali, MN Stein, S Murphy, H Vig, ... The oncologist 21 (11), 1315-1325, 2016 | 79 | 2016 |
| The evolution of thymic lymphomas in p53 knockout mice C Dudgeon, C Chan, W Kang, Y Sun, R Emerson, H Robins, AJ Levine Genes & development 28 (23), 2613-2620, 2014 | 77 | 2014 |
| Autophagy promotes growth of tumors with high mutational burden by inhibiting a T-cell immune response L Poillet-Perez, DW Sharp, Y Yang, SV Laddha, M Ibrahim, ... Nature cancer 1 (9), 923-934, 2020 | 73 | 2020 |
| The bromodomain and extra-terminal inhibitor CPI203 enhances the antiproliferative effects of rapamycin on human neuroendocrine tumors C Wong, SV Laddha, L Tang, E Vosburgh, AJ Levine, E Normant, ... Cell death & disease 5 (10), e1450-e1450, 2014 | 70 | 2014 |
| MicroRNA-339-5p inhibits colorectal tumorigenesis through regulation of the MDM2/p53 signaling C Zhang, J Liu, X Wang, R Wu, M Lin, SV Laddha, Q Yang, CS Chan, ... Oncotarget 5 (19), 9106, 2014 | 58 | 2014 |
| Integrative genomic characterization identifies molecular subtypes of lung carcinoids SV Laddha, EM Da Silva, K Robzyk, BR Untch, H Ke, N Rekhtman, ... Cancer research 79 (17), 4339-4347, 2019 | 57 | 2019 |
| The role of the p53 protein in stem-cell biology and epigenetic regulation AJ Levine, AM Puzio-Kuter, CS Chan, P Hainaut Cold Spring Harbor perspectives in medicine 6 (9), a026153, 2016 | 49 | 2016 |
| microRNA-1827 represses MDM2 to positively regulate tumor suppressor p53 and suppress tumorigenesis C Zhang, J Liu, C Tan, X Yue, Y Zhao, J Peng, X Wang, SV Laddha, ... Oncotarget 7 (8), 8783, 2016 | 48 | 2016 |
| Function and clinical relevance of RHAMM isoforms in pancreatic tumor progression S Choi, D Wang, X Chen, LH Tang, A Verma, Z Chen, BJ Kim, L Selesner, ... Molecular cancer 18, 1-7, 2019 | 46 | 2019 |
