| Toxic gain of function from mutant FUS protein is crucial to trigger cell autonomous motor neuron loss J Scekic‐Zahirovic, O Sendscheid, H El Oussini, M Jambeau, Y Sun, ... The EMBO journal 35 (10), 1077-1097, 2016 | 240 | 2016 |
| Fused in Sarcoma (FUS) Protein Lacking Nuclear Localization Signal (NLS) and Major RNA Binding Motifs Triggers Proteinopathy and Severe Motor Phenotype in Transgenic Mice*♦ TA Shelkovnikova, OM Peters, AV Deykin, N Connor-Robson, ... Journal of biological chemistry 288 (35), 25266-25274, 2013 | 148 | 2013 |
| Compromised paraspeckle formation as a pathogenic factor in FUSopathies TA Shelkovnikova, HK Robinson, C Troakes, N Ninkina, VL Buchman Human molecular genetics 23 (9), 2298-2312, 2014 | 131 | 2014 |
| ALS-linked FUS mutations confer loss and gain of function in the nucleus by promoting excessive formation of dysfunctional paraspeckles H An, L Skelt, A Notaro, JR Highley, AH Fox, V La Bella, VL Buchman, ... Acta neuropathologica communications 7, 1-14, 2019 | 126 | 2019 |
| Multistep process of FUS aggregation in the cell cytoplasm involves RNA-dependent and RNA-independent mechanisms TA Shelkovnikova, HK Robinson, JA Southcombe, N Ninkina, ... Human molecular genetics 23 (19), 5211-5226, 2014 | 105 | 2014 |
| NEAT1 and paraspeckles in neurodegenerative diseases: A missing lnc found? H An, NG Williams, TA Shelkovnikova Non-coding RNA research 3 (4), 243-252, 2018 | 102 | 2018 |
| Protective paraspeckle hyper-assembly downstream of TDP-43 loss of function in amyotrophic lateral sclerosis TA Shelkovnikova, MS Kukharsky, H An, P Dimasi, S Alexeeva, O Shabir, ... Molecular neurodegeneration 13, 1-17, 2018 | 92 | 2018 |
| Recruitment into stress granules prevents irreversible aggregation of FUS protein mislocalized to the cytoplasm TA Shelkovnikova, HK Robinson, N Connor-Robson, VL Buchman Cell Cycle 12 (19), 3383-3391, 2013 | 75 | 2013 |
| Stress granules regulate stress-induced paraspeckle assembly H An, JT Tan, TA Shelkovnikova Journal of Cell Biology 218 (12), 4127-4140, 2019 | 72 | 2019 |
| Dimebon slows progression of proteinopathy in γ-synuclein transgenic mice SO Bachurin, TA Shelkovnikova, AA Ustyugov, O Peters, I Khritankova, ... Neurotoxicity research 22, 33-42, 2012 | 58 | 2012 |
| Proteinopathies, neurodegenerative disorders with protein aggregation-based pathology TA Shelkovnikova, AA Kulikova, PO Tsvetkov, O Peters, SO Bachurin, ... Molecular Biology 46, 362-374, 2012 | 57* | 2012 |
| Long non-coding RNA Neat1 regulates adaptive behavioural response to stress in mice MS Kukharsky, NN Ninkina, H An, V Telezhkin, W Wei, CR Meritens, ... Translational psychiatry 10 (1), 171, 2020 | 53 | 2020 |
| Chronically stressed or stress-preconditioned neurons fail to maintain stress granule assembly TA Shelkovnikova, P Dimasi, MS Kukharsky, H An, A Quintiero, ... Cell death & disease 8 (5), e2788-e2788, 2017 | 51 | 2017 |
| Selective pattern of motor system damage in gamma-synuclein transgenic mice mirrors the respective pathology in amyotrophic lateral sclerosis OM Peters, S Millership, TA Shelkovnikova, I Soto, L Keeling, A Hann, ... Neurobiology of disease 48 (1), 124-131, 2012 | 42 | 2012 |
| Antiviral immune response as a trigger of FUS proteinopathy in amyotrophic lateral sclerosis TA Shelkovnikova, H An, L Skelt, JS Tregoning, IR Humphreys, ... Cell reports 29 (13), 4496-4508. e4, 2019 | 40 | 2019 |
| Long non-coding RNA NEAT1_1 ameliorates TDP-43 toxicity in in vivo models of TDP-43 proteinopathy K Matsukawa, MS Kukharsky, SK Park, S Park, N Watanabe, T Iwatsubo, ... RNA biology 18 (11), 1546-1554, 2021 | 34 | 2021 |
| Gamma‐synuclein pathology in amyotrophic lateral sclerosis OM Peters, T Shelkovnikova, JR Highley, J Cooper‐Knock, T Hortobágyi, ... Annals of Clinical and Translational Neurology 2 (1), 29-37, 2015 | 34 | 2015 |
| Chronic administration of Dimebon does not ameliorate amyloid-β pathology in 5xFAD transgenic mice OM Peters, T Shelkovnikova, T Tarasova, S Springe, MS Kukharsky, ... Journal of Alzheimer's Disease 36 (3), 589-596, 2013 | 34 | 2013 |
| Hindering of proteinopathy-induced neurodegeneration as a new mechanism of action for neuroprotectors and cognition enhancing compounds. SO Bachurin, AA Ustyugov, O Peters, TA Shelkovnikova, VL Buchman, ... Doklady Biochemistry & Biophysics 428 (1), 2009 | 32 | 2009 |
| Modulation of p-eIF2α cellular levels and stress granule assembly/disassembly by trehalose P Dimasi, A Quintiero, TA Shelkovnikova, VL Buchman Scientific Reports 7 (1), 44088, 2017 | 31 | 2017 |
