| Notch inhibition induces cochlear hair cell regeneration and recovery of hearing after acoustic trauma K Mizutari, M Fujioka, M Hosoya, N Bramhall, HJ Okano, H Okano, ... Neuron 77 (1), 58-69, 2013 | 468 | 2013 |
| Proinflammatory cytokines expression in noise‐induced damaged cochlea M Fujioka, S Kanzaki, HJ Okano, M Masuda, K Ogawa, H Okano Journal of neuroscience research 83 (4), 575-583, 2006 | 344 | 2006 |
| Blockade of interleukin-6 signaling suppressed cochlear inflammatory response and improved hearing impairment in noise-damaged mice cochlea K Wakabayashi, M Fujioka, S Kanzaki, HJ Okano, S Shibata, D Yamashita, ... Neuroscience research 66 (4), 345-352, 2010 | 198 | 2010 |
| Megakaryocytes are essential for HSC quiescence through the production of thrombopoietin A Nakamura-Ishizu, K Takubo, M Fujioka, T Suda Biochemical and biophysical research communications 454 (2), 353-357, 2014 | 167 | 2014 |
| Inflammatory and immune responses in the cochlea: potential therapeutic targets for sensorineural hearing loss M Fujioka, H Okano, K Ogawa Frontiers in pharmacology 5, 287, 2014 | 127 | 2014 |
| Notch signaling alters sensory or neuronal cell fate specification of inner ear stem cells SJ Jeon, M Fujioka, SC Kim, ASB Edge Journal of Neuroscience 31 (23), 8351-8358, 2011 | 126 | 2011 |
| Nuclear factor-kappa B nuclear translocation in the cochlea of mice following acoustic overstimulation M Masuda, R Nagashima, S Kanzaki, M Fujioka, K Ogita, K Ogawa Brain research 1068 (1), 237-247, 2006 | 94 | 2006 |
| Cochlear cell modeling using disease-specific iPSCs unveils a degenerative phenotype and suggests treatments for congenital progressive hearing loss M Hosoya, M Fujioka, T Sone, S Okamoto, W Akamatsu, H Ukai, HR Ueda, ... Cell reports 18 (1), 68-81, 2017 | 80 | 2017 |
| Distinct expression patterns of causative genes responsible for hereditary progressive hearing loss in non-human primate cochlea M Hosoya, M Fujioka, K Ogawa, H Okano Scientific reports 6 (1), 22250, 2016 | 60 | 2016 |
| Autophagy is essential for hearing in mice C Fujimoto, S Iwasaki, S Urata, H Morishita, Y Sakamaki, M Fujioka, ... Cell death & disease 8 (5), e2780-e2780, 2017 | 57 | 2017 |
| The autophagy pathway maintained signaling crosstalk with the Keap1–Nrf2 system through p62 in auditory cells under oxidative stress K Hayashi, K Dan, F Goto, N Tshuchihashi, Y Nomura, M Fujioka, ... Cellular signalling 27 (2), 382-393, 2015 | 56 | 2015 |
| Manipulating cell fate in the cochlea: a feasible therapy for hearing loss M Fujioka, H Okano, ASB Edge Trends in neurosciences 38 (3), 139-144, 2015 | 47 | 2015 |
| Therapeutic agents for inner ear disorders containing an IL-6 antagonist as an active ingredient M Fujioka, HJ Okano, K Ogawa, H Okano, S Kanzaki US Patent 7,498,031, 2009 | 46 | 2009 |
| ERK2 mediates inner hair cell survival and decreases susceptibility to noise-induced hearing loss T Kurioka, T Matsunobu, Y Satoh, K Niwa, S Endo, M Fujioka, A Shiotani Scientific reports 5 (1), 16839, 2015 | 43 | 2015 |
| A VEGF receptor vaccine demonstrates preliminary efficacy in neurofibromatosis type 2 R Tamura, M Fujioka, Y Morimoto, K Ohara, K Kosugi, Y Oishi, M Sato, ... Nature communications 10 (1), 5758, 2019 | 42 | 2019 |
| Novel in vivo imaging analysis of an inner ear drug delivery system in mice: comparison of inner ear drug concentrations over time after transtympanic and systemic injections S Kanzaki, M Fujioka, A Yasuda, S Shibata, M Nakamura, HJ Okano, ... PloS one 7 (12), e48480, 2012 | 42 | 2012 |
| Autophagy through 4EBP1 and AMPK regulates oxidative stress-induced premature senescence in auditory cells NA Tsuchihashi, K Hayashi, K Dan, F Goto, Y Nomura, M Fujioka, ... Oncotarget 6 (6), 3644, 2015 | 41 | 2015 |
| Comprehensive analysis of syndromic hearing loss patients in Japan M Ideura, S Nishio, H Moteki, Y Takumi, M Miyagawa, T Sato, ... Scientific reports 9 (1), 11976, 2019 | 36 | 2019 |
| Estimating the concentration of therapeutic range using disease-specific iPS cells: low-dose rapamycin therapy for Pendred syndrome M Hosoya, T Saeki, C Saegusa, T Matsunaga, H Okano, M Fujioka, ... Regenerative therapy 10, 54-63, 2019 | 30 | 2019 |
| Engraftment of human pluripotent stem cell-derived progenitors in the inner ear of prenatal mice H Takeda, M Hosoya, M Fujioka, C Saegusa, T Saeki, T Miwa, H Okano, ... Scientific reports 8 (1), 1941, 2018 | 29 | 2018 |
