| Lens aging: effects of crystallins KK Sharma, P Santhoshkumar Biochimica et Biophysica Acta (BBA)-General Subjects 1790 (10), 1095-1108, 2009 | 389 | 2009 |
| Significance of interactions of low molecular weight crystallin fragments in lens aging and cataract formation P Santhoshkumar, P Udupa, R Murugesan, KK Sharma Journal of Biological Chemistry 283 (13), 8477-8485, 2008 | 108 | 2008 |
| Chaperone peptides of α-crystallin inhibit epithelial cell apoptosis, protein insolubilization, and opacification in experimental cataracts RB Nahomi, B Wang, CT Raghavan, O Voss, AI Doseff, P Santhoshkumar, ... Journal of Biological Chemistry 288 (18), 13022-13035, 2013 | 93 | 2013 |
| Inhibition of amyloid fibrillogenesis and toxicity by a peptide chaperone P Santhoshkumar, KK Sharma Molecular and cellular biochemistry 267, 147-155, 2004 | 89 | 2004 |
| αA-crystallin peptide 66 SDRDKFVIFLDVKHF 80 accumulating in aging lens impairs the function of α-crystallin and induces lens protein aggregation P Santhoshkumar, M Raju, KK Sharma PloS one 6 (4), e19291, 2011 | 75 | 2011 |
| Acetylation of αA-crystallin in the human lens: effects on structure and chaperone function RH Nagaraj, RB Nahomi, S Shanthakumar, M Linetsky, S Padmanabha, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1822 (2), 120-129, 2012 | 71 | 2012 |
| Phe71 is essential for chaperone-like function in αA-crystallin P Santhoshkumar, KK Sharma Journal of Biological Chemistry 276 (50), 47094-47099, 2001 | 70 | 2001 |
| Effect of site-directed mutagenesis of methylglyoxal-modifiable arginine residues on the structure and chaperone function of human αA-crystallin A Biswas, A Miller, T Oya-Ito, P Santhoshkumar, M Bhat, RH Nagaraj Biochemistry 45 (14), 4569-4577, 2006 | 60 | 2006 |
| Failure of oxysterols such as lanosterol to restore lens clarity from cataracts DM Daszynski, P Santhoshkumar, AS Phadte, KK Sharma, HA Zhong, ... Scientific reports 9 (1), 8459, 2019 | 57 | 2019 |
| In vitro sequestration of two organophosphorus homologs by the rat liver P Santhoshkumar, T Shivanandappa Chemico-biological interactions 119, 277-282, 1999 | 48 | 1999 |
| Effect of a single AGE modification on the structure and chaperone activity of human αB-crystallin J Bhattacharyya, EV Shipova, P Santhoshkumar, KK Sharma, BJ Ortwerth Biochemistry 46 (50), 14682-14692, 2007 | 45 | 2007 |
| Hydroimidazolone modification of the conserved Arg12 in small heat shock proteins: studies on the structure and chaperone function using mutant mimics RH Nagaraj, AK Panda, S Shanthakumar, P Santhoshkumar, ... PloS one 7 (1), e30257, 2012 | 44 | 2012 |
| αA-Crystallin interacting regions in the small heat shock protein, αB-crystallin Y Sreelakshmi, P Santhoshkumar, J Bhattacharyya, KK Sharma Biochemistry 43 (50), 15785-15795, 2004 | 44 | 2004 |
| Alpha-crystallin-derived peptides as therapeutic chaperones M Raju, P Santhoshkumar, KK Sharma Biochimica et Biophysica Acta (BBA)-General Subjects 1860 (1), 246-251, 2016 | 43 | 2016 |
| Histone deacetylase inhibitors trichostatin A and vorinostat inhibit TGFβ2-induced lens epithelial-to-mesenchymal cell transition L Xie, P Santhoshkumar, LW Reneker, KK Sharma Investigative ophthalmology & visual science 55 (8), 4731-4740, 2014 | 43 | 2014 |
| Analysis of alpha-crystallin chaperone function using restriction enzymes and citrate synthase P Santhoshkumar, KK Sharma Mol Vis 7, 172-177, 2001 | 40 | 2001 |
| Cataract-causing alphaAG98R mutant shows substrate-dependent chaperone activity R Murugesan, P Santhoshkumar, KK Sharma Mol Vis 13, 2301-9, 2007 | 35 | 2007 |
| Cleavage of the C-Terminal Serine of Human αA-Crystallin Produces αA1-172 with Increased Chaperone Activity and Oligomeric Size A Aziz, P Santhoshkumar, KK Sharma, EC Abraham Biochemistry 46 (9), 2510-2519, 2007 | 34 | 2007 |
| Acetylation of lysine 92 improves the chaperone and anti-apoptotic activities of human αB-crystallin RB Nahomi, R Huang, SK Nandi, B Wang, S Padmanabha, ... Biochemistry 52 (45), 8126-8138, 2013 | 33 | 2013 |
| A peptide sequence—YSGVCHTDLHAWHGDWPLPVK [40–60]—in yeast alcohol dehydrogenase prevents the aggregation of denatured substrate proteins J Bhattacharyya, P Santhoshkumar, KK Sharma Biochemical and biophysical research communications 307 (1), 1-7, 2003 | 33 | 2003 |
