Targeting GLP-1 receptor trafficking to improve agonist efficacy B Jones, T Buenaventura, N Kanda, P Chabosseau, BM Owen, R Scott, ... Nature communications 9 (1), 1602, 2018 | 200 | 2018 |
Zinc and diabetes P Chabosseau, GA Rutter Archives of biochemistry and biophysics 611, 79-85, 2016 | 199 | 2016 |
The α-cell in diabetes mellitus J Gromada, P Chabosseau, GA Rutter Nature Reviews Endocrinology 14 (12), 694-704, 2018 | 151 | 2018 |
The zinc transporter ZIP12 regulates the pulmonary vascular response to chronic hypoxia L Zhao, E Oliver, K Maratou, SS Atanur, OD Dubois, E Cotroneo, ... Nature 524 (7565), 356-360, 2015 | 142 | 2015 |
Mitochondrial and ER-Targeted eCALWY Probes Reveal High Levels of Free Zn2+ P Chabosseau, E Tuncay, G Meur, EA Bellomo, A Hessels, S Hughes, ... ACS chemical biology 9 (9), 2111-2120, 2014 | 130 | 2014 |
Loss of ZnT8 function protects against diabetes by enhanced insulin secretion OP Dwivedi, M Lehtovirta, B Hastoy, V Chandra, NAJ Krentz, S Kleiner, ... Nature genetics 51 (11), 1596-1606, 2019 | 126 | 2019 |
An essential role for the Zn2+ transporter ZIP7 in B cell development C Anzilotti, DJ Swan, B Boisson, M Deobagkar-Lele, C Oliveira, ... Nature immunology 20 (3), 350-361, 2019 | 126 | 2019 |
eZinCh-2: A Versatile, Genetically Encoded FRET Sensor for Cytosolic and Intraorganelle Zn2+ Imaging AM Hessels, P Chabosseau, MH Bakker, W Engelen, GA Rutter, ... ACS chemical biology 10 (9), 2126-2134, 2015 | 106 | 2015 |
Pyrimidine pool imbalance induced by BLM helicase deficiency contributes to genetic instability in Bloom syndrome P Chabosseau, G Buhagiar-Labarchède, R Onclercq-Delic, S Lambert, ... Nature communications 2 (1), 368, 2011 | 101 | 2011 |
SLC30A9 mutation affecting intracellular zinc homeostasis causes a novel cerebro-renal syndrome Y Perez, Z Shorer, K Liani-Leibson, P Chabosseau, R Kadir, ... Brain 140 (4), 928-939, 2017 | 98 | 2017 |
Intracellular zinc in insulin secretion and action: a determinant of diabetes risk? GA Rutter, P Chabosseau, EA Bellomo, W Maret, RK Mitchell, DJ Hodson, ... Proceedings of the Nutrition Society 75 (1), 61-72, 2016 | 96 | 2016 |
Molecular Genetic Regulation of Slc30a8/ZnT8 Reveals a Positive Association With Glucose Tolerance RK Mitchell, M Hu, PL Chabosseau, MC Cane, G Meur, EA Bellomo, ... Molecular Endocrinology 30 (1), 77-91, 2016 | 76 | 2016 |
Decreased STARD10 expression is associated with defective insulin secretion in humans and mice GR Carrat, M Hu, MS Nguyen-Tu, P Chabosseau, KJ Gaulton, ... The American Journal of Human Genetics 100 (2), 238-256, 2017 | 71 | 2017 |
Mice harboring the human SLC30A8 R138X loss-of-function mutation have increased insulin secretory capacity S Kleiner, D Gomez, B Megra, E Na, R Bhavsar, K Cavino, Y Xin, J Rojas, ... Proceedings of the National Academy of Sciences 115 (32), E7642-E7649, 2018 | 69 | 2018 |
The transcription factor Pax6 is required for pancreatic β cell identity, glucose-regulated ATP synthesis, and Ca2+ dynamics in adult mice RK Mitchell, MS Nguyen-Tu, P Chabosseau, RM Callingham, TJ Pullen, ... Journal of Biological Chemistry 292 (21), 8892-8906, 2017 | 65 | 2017 |
Neuronatin regulates pancreatic β cell insulin content and secretion SJ Millership, GDS Xavier, AI Choudhury, S Bertazzo, P Chabosseau, ... The Journal of clinical investigation 128 (8), 3369-3381, 2018 | 61 | 2018 |
Local and regional control of calcium dynamics in the pancreatic islet GA Rutter, DJ Hodson, P Chabosseau, E Haythorne, TJ Pullen, I Leclerc Diabetes, Obesity and Metabolism 19, 30-41, 2017 | 60 | 2017 |
Divergent effects of liraglutide, exendin-4, and sitagliptin on beta-cell mass and indicators of pancreatitis in a mouse model of hyperglycaemia A Mondragon, D Davidsson, S Kyriakoudi, A Bertling, R Gomes-Faria, ... PloS one 9 (8), e104873, 2014 | 46 | 2014 |
Sensors for measuring subcellular zinc pools P Chabosseau, J Woodier, R Cheung, GA Rutter Metallomics 10 (2), 229-239, 2018 | 41 | 2018 |
A targeted RNAi screen identifies endocytic trafficking factors that control GLP-1 receptor signaling in pancreatic β-cells T Buenaventura, N Kanda, PC Douzenis, B Jones, SR Bloom, ... Diabetes 67 (3), 385-399, 2018 | 38 | 2018 |