| Molecular mechanism of the interaction between MDM2 and p53 O Schon, A Friedler, M Bycroft, SMV Freund, AR Fersht Journal of molecular biology 323 (3), 491-501, 2002 | 450 | 2002 |
| A peptide that binds and stabilizes p53 core domain: chaperone strategy for rescue of oncogenic mutants A Friedler, LO Hansson, DB Veprintsev, SMV Freund, TM Rippin, ... Proceedings of the National Academy of Sciences 99 (2), 937-942, 2002 | 345 | 2002 |
| Studying protein–protein interactions using peptide arrays C Katz, L Levy-Beladev, S Rotem-Bamberger, T Rito, SGD Rüdiger, ... Chemical Society Reviews 40 (5), 2131-2145, 2011 | 236 | 2011 |
| Inhibiting HIV-1 integrase by shifting its oligomerization equilibrium Z Hayouka, J Rosenbluh, A Levin, S Loya, M Lebendiker, D Veprintsev, ... Proceedings of the National Academy of Sciences 104 (20), 8316-8321, 2007 | 233 | 2007 |
| Butyrylcholinesterase attenuates amyloid fibril formation in vitro S Diamant, E Podoly, A Friedler, H Ligumsky, O Livnah, H Soreq Proceedings of the National Academy of Sciences 103 (23), 8628-8633, 2006 | 202 | 2006 |
| Rescue of mutants of the tumor suppressor p53 in cancer cells by a designed peptide N Issaeva, A Friedler, P Bozko, KG Wiman, AR Fersht, G Selivanova Proceedings of the National Academy of Sciences 100 (23), 13303-13307, 2003 | 193 | 2003 |
| The C terminus of p53 binds the N-terminal domain of MDM2 MV Poyurovsky, C Katz, O Laptenko, R Beckerman, M Lokshin, J Ahn, ... Nature structural & molecular biology 17 (8), 982-989, 2010 | 174 | 2010 |
| Two sequence motifs from HIF-1α bind to the DNA-binding site of p53 LO Hansson, A Friedler, S Freund, S Rüdiger, AR Fersht Proceedings of the National Academy of Sciences 99 (16), 10305-10309, 2002 | 170 | 2002 |
| Kinetic instability of p53 core domain mutants: implications for rescue by small molecules A Friedler, DB Veprintsev, LO Hansson, AR Fersht Journal of Biological Chemistry 278 (26), 24108-24112, 2003 | 169 | 2003 |
| Modulation of binding of DNA to the C-terminal domain of p53 by acetylation A Friedler, DB Veprintsev, SMV Freund, KI von Glos, AR Fersht Structure 13 (4), 629-636, 2005 | 113 | 2005 |
| Distinct G protein-coupled receptor phosphorylation motifs modulate arrestin affinity and activation and global conformation D Mayer, FF Damberger, M Samarasimhareddy, M Feldmueller, ... Nature communications 10 (1), 1261, 2019 | 110 | 2019 |
| The structure of an FF domain from human HYPA/FBP11 M Allen, A Friedler, O Schon, M Bycroft Journal of molecular biology 323 (3), 411-416, 2002 | 107 | 2002 |
| Structural distortion of p53 by the mutation R249S and its rescue by a designed peptide: implications for “mutant conformation” A Friedler, BS DeDecker, SMV Freund, C Blair, S Rüdiger, AR Fersht Journal of molecular biology 336 (1), 187-196, 2004 | 86 | 2004 |
| Cyclic peptide inhibitors of HIV-1 integrase derived from the LEDGF/p75 protein Z Hayouka, M Hurevich, A Levin, H Benyamini, A Iosub, M Maes, ... Bioorganic & medicinal chemistry 18 (23), 8388-8395, 2010 | 81 | 2010 |
| Chemical synthesis and expression of the HIV‐1 Rev protein P Siman, O Blatt, T Moyal, T Danieli, M Lebendiker, HA Lashuel, ... ChemBioChem 12 (7), 1097-1104, 2011 | 80 | 2011 |
| Agonist-induced dimer dissociation as a macromolecular step in G protein-coupled receptor signaling J Petersen, SC Wright, D Rodríguez, P Matricon, N Lahav, A Vromen, ... Nature communications 8 (1), 226, 2017 | 79 | 2017 |
| Binding of p53-derived ligands to MDM2 induces a variety of long range conformational changes O Schon, A Friedler, S Freund, AR Fersht Journal of molecular biology 336 (1), 197-202, 2004 | 78 | 2004 |
| Development of a functional backbone cyclic mimetic of the HIV-1 Tat arginine-rich motif A Friedler, D Friedler, NW Luedtke, Y Tor, A Loyter, C Gilon Journal of biological chemistry 275 (31), 23783-23789, 2000 | 78 | 2000 |
| Backbone cyclic peptide, which mimics the nuclear localization signal of human immunodeficiency virus type 1 matrix protein, inhibits nuclear import and virus production in … A Friedler, N Zakai, O Karni, YC Broder, L Baraz, M Kotler, A Loyter, ... Biochemistry 37 (16), 5616-5622, 1998 | 78 | 1998 |
| Observation of signal transduction in three-dimensional domain swapping JWH Schymkowitz, F Rousseau, HR Wilkinson, A Friedler, LS Itzhaki nature structural biology 8 (10), 888-892, 2001 | 76 | 2001 |
Zvi HayoukaThe Robert H. Smith Faculty of Agriculture, Food and Environment,The Hebrew University of Jerusalem在 mail.huji.ac.il 的电子邮件经过验证
