Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments GR Masson, JE Burke, NG Ahn, GS Anand, C Borchers, S Brier, ... Nature methods 16 (7), 595-602, 2019 | 561 | 2019 |
Protein hydrogen exchange measured at single-residue resolution by electron transfer dissociation mass spectrometry KD Rand, M Zehl, ON Jensen, TJD Jørgensen Analytical chemistry 81 (14), 5577-5584, 2009 | 236 | 2009 |
Electron capture dissociation proceeds with a low degree of intramolecular migration of peptide amide hydrogens KD Rand, CM Adams, RA Zubarev, TJD Jørgensen Journal of the American Chemical Society 130 (4), 1341-1349, 2008 | 202 | 2008 |
Electron transfer dissociation facilitates the measurement of deuterium incorporation into selectively labeled peptides with single residue resolution M Zehl, KD Rand, ON Jensen, TJD Jørgensen Journal of the American Chemical Society 130 (51), 17453-17459, 2008 | 192 | 2008 |
Conformational analysis of membrane proteins in phospholipid bilayer nanodiscs by hydrogen exchange mass spectrometry CM Hebling, CR Morgan, DW Stafford, JW Jorgenson, KD Rand, ... Analytical chemistry 82 (13), 5415-5419, 2010 | 170 | 2010 |
First community-wide, comparative cross-linking mass spectrometry study C Iacobucci, C Piotrowski, R Aebersold, BC Amaral, P Andrews, K Bernfur, ... Analytical chemistry 91 (11), 6953-6961, 2019 | 131 | 2019 |
False EX1 signatures caused by sample carryover during HX MS analyses J Fang, KD Rand, PJ Beuning, JR Engen International journal of mass spectrometry 302 (1-3), 19-25, 2011 | 114 | 2011 |
Measuring the hydrogen/deuterium exchange of proteins at high spatial resolution by mass spectrometry: overcoming gas-phase hydrogen/deuterium scrambling KD Rand, M Zehl, TJD Jørgensen Accounts of chemical research 47 (10), 3018-3027, 2014 | 110 | 2014 |
Gas-phase hydrogen/deuterium exchange in a traveling wave ion guide for the examination of protein conformations KD Rand, SD Pringle, JP Murphy III, KE Fadgen, J Brown, JR Engen Analytical chemistry 81 (24), 10019-10028, 2009 | 105 | 2009 |
Conformational analysis of complex protein states by hydrogen/deuterium exchange mass spectrometry (HDX-MS): Challenges and emerging solutions E Trabjerg, ZE Nazari, KD Rand TrAC Trends in Analytical Chemistry 106, 125-138, 2018 | 101 | 2018 |
Antibody mechanics on a membrane-bound HIV segment essential for GP41-targeted viral neutralization M Kim, ZYJ Sun, KD Rand, X Shi, L Song, Y Cheng, AF Fahmy, ... Nature structural & molecular biology 18 (11), 1235-1243, 2011 | 100 | 2011 |
Investigating the interaction between the neonatal Fc receptor and monoclonal antibody variants by hydrogen/deuterium exchange mass spectrometry PF Jensen, V Larraillet, T Schlothauer, H Kettenberger, M Hilger, ... Molecular & Cellular Proteomics 14 (1), 148-161, 2015 | 99 | 2015 |
Development of a peptide probe for the occurrence of hydrogen (1H/2H) scrambling upon gas-phase fragmentation KD Rand, TJD Jørgensen Analytical chemistry 79 (22), 8686-8693, 2007 | 93 | 2007 |
Conformational transitions in the membrane scaffold protein of phospholipid bilayer nanodiscs CR Morgan, CM Hebling, KD Rand, DW Stafford, JW Jorgenson, ... Molecular & Cellular Proteomics 10 (9), 2011 | 92 | 2011 |
A poly-ADP-ribose trigger releases the auto-inhibition of a chromatin remodeling oncogene HR Singh, AP Nardozza, IR Möller, G Knobloch, HAV Kistemaker, ... Molecular cell 68 (5), 860-871. e7, 2017 | 91 | 2017 |
ETD in a traveling wave ion guide at tuned Z-spray ion source conditions allows for site-specific hydrogen/deuterium exchange measurements KD Rand, SD Pringle, M Morris, JR Engen, JM Brown Journal of the American Society for Mass Spectrometry 22 (10), 2011 | 86 | 2011 |
Molecular analysis of the interaction between the hematopoietic master transcription factors GATA-1 and PU. 1 CW Liew, KD Rand, RJY Simpson, WW Yung, RE Mansfield, M Crossley, ... Journal of Biological Chemistry 281 (38), 28296-28306, 2006 | 80 | 2006 |
Site-specific analysis of gas-phase hydrogen/deuterium exchange of peptides and proteins by electron transfer dissociation KD Rand, SD Pringle, M Morris, JM Brown Analytical chemistry 84 (4), 1931-1940, 2012 | 75 | 2012 |
Getting to the core of protein pharmaceuticals–comprehensive structure analysis by mass spectrometry U Leurs, UH Mistarz, KD Rand European Journal of Pharmaceutics and Biopharmaceutics 93, 95-109, 2015 | 72 | 2015 |
Conformational dynamics of the human serotonin transporter during substrate and drug binding IR Möller, M Slivacka, AK Nielsen, SGF Rasmussen, U Gether, CJ Loland, ... Nature communications 10 (1), 1687, 2019 | 69 | 2019 |