Hip14l-deficient mice develop neuropathological and behavioural features of Huntington disease LM Sutton, SS Sanders, SL Butland, RR Singaraja, S Franciosi, ... Human molecular genetics 22 (3), 452-465, 2013 | 77 | 2013 |
The palmitoyl acyltransferase HIP14 shares a high proportion of interactors with huntingtin: implications for a role in the pathogenesis of Huntington's disease SL Butland, SS Sanders, ME Schmidt, SP Riechers, DTS Lin, DDO Martin, ... Human molecular genetics 23 (15), 4142-4160, 2014 | 72 | 2014 |
Preventing mutant huntingtin proteolysis and intermittent fasting promote autophagy in models of Huntington disease DE Ehrnhoefer, DDO Martin, ME Schmidt, X Qiu, S Ladha, NS Caron, ... Acta neuropathologica communications 6, 1-16, 2018 | 56 | 2018 |
Western Database of Lipid Variants (WDLV): a catalogue of genetic variants in monogenic dyslipidemias J Fu, S Kwok, L Sinai, O Abdel-Razek, J Babula, D Chen, E Farago, ... Canadian Journal of Cardiology 29 (8), 934-939, 2013 | 33 | 2013 |
The Interaction of Aging and Cellular Stress Contributes to Pathogenesis in Mouse and Human Huntington Disease Neurons E Machiela, R Jeloka, NS Caron, S Mehta, ME Schmidt, HJE Baddeley, ... Frontiers in Aging Neuroscience 12, 288, 2020 | 26 | 2020 |
Identification of a novel caspase cleavage site in huntingtin that regulates mutant huntingtin clearance DDO Martin, ME Schmidt, YT Nguyen, N Lazic, MR Hayden The FASEB Journal 33 (3), 3190-3197, 2019 | 23 | 2019 |
Altering cortical input unmasks synaptic phenotypes in the YAC128 cortico-striatal co-culture model of Huntington disease ME Schmidt, C Buren, JP Mackay, D Cheung, L Dal Cengio, LA Raymond, ... BMC Biology 16 (1), 58, 2018 | 21 | 2018 |
Rescue of aberrant huntingtin palmitoylation ameliorates mutant huntingtin-induced toxicity FL Lemarié, NS Caron, SS Sanders, ME Schmidt, YTN Nguyen, S Ko, ... Neurobiology of Disease 158, 105479, 2021 | 19 | 2021 |
DAPK1 promotes extrasynaptic GluN2B phosphorylation and striatal spine instability in the YAC128 mouse model of Huntington disease ME Schmidt, NS Caron, AE Aly, FL Lemarié, L Dal Cengio, Y Ko, N Lazic, ... Frontiers in Cellular Neuroscience 14, 348, 2020 | 14 | 2020 |
Axonal ER Ca2+ Release Selectively Enhances Activity-Independent Glutamate Release in a Huntington Disease Model JP Mackay, AI Smith-Dijak, ET Koch, P Zhang, E Fung, WB Nassrallah, ... Journal of Neuroscience 43 (20), 3743-3763, 2023 | 4 | 2023 |
Delivery of mutant huntingtin-lowering antisense oligonucleotides to the brain by intranasally administered apolipoprotein AI nanodisks AEE Aly, NS Caron, HF Black, ME Schmidt, C Anderson, S Ko, ... Journal of Controlled Release 360, 913-927, 2023 | 3 | 2023 |
Systemic delivery of mutant huntingtin lowering antisense oligonucleotides to the brain using apolipoprotein AI nanodisks for Huntington disease NS Caron, AEE Aly, HF Black, DDO Martin, ME Schmidt, S Ko, ... Journal of Controlled Release 367, 27-44, 2024 | 2 | 2024 |
Understanding and modulating synaptic dysfunction in Huntington disease ME Schmidt University of British Columbia, 2019 | | 2019 |