NADPH oxidase-4 mediates myofibroblast activation and fibrogenic responses to lung injury L Hecker, R Vittal, T Jones, R Jagirdar, TR Luckhardt, JC Horowitz, ... Nature medicine 15 (9), 1077-1081, 2009 | 899 | 2009 |
Mechanosignaling through YAP and TAZ drives fibroblast activation and fibrosis F Liu, D Lagares, KM Choi, L Stopfer, A Marinković, V Vrbanac, CK Probst, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 308 (4 …, 2015 | 753 | 2015 |
Myofibroblast differentiation by transforming growth factor-ॆ1 Is dependent on cell adhesion and integrin signaling via focal adhesion kinase VJ Thannickal, DY Lee, ES White, Z Cui, JM Larios, R Chacon, ... Journal of Biological Chemistry 278 (14), 12384-12389, 2003 | 710 | 2003 |
Acellular normal and fibrotic human lung matrices as a culture system for in vitro investigation AJ Booth, R Hadley, AM Cornett, AA Dreffs, SA Matthes, JL Tsui, K Weiss, ... American journal of respiratory and critical care medicine 186 (9), 866-876, 2012 | 701 | 2012 |
Evolving concepts of apoptosis in idiopathic pulmonary fibrosis VJ Thannickal, JC Horowitz Proceedings of the American Thoracic Society 3 (4), 350-356, 2006 | 425 | 2006 |
Hydrogen peroxide is a diffusible paracrine signal for the induction of epithelial cell death by activated myofibroblasts M Waghray, Z Cui, JC Horowitz, IM Subramanian, FJ Martinez, GB Toews, ... Wiley Periodicals, Inc., 2005 | 336 | 2005 |
What's in a name? That which we call IPF, by any other name would act the same AU Wells, KK Brown, KR Flaherty, M Kolb, VJ Thannickal European Respiratory Journal 51 (5), 2018 | 313 | 2018 |
Activation of the pro-survival phosphatidylinositol 3-kinase/AKT pathway by transforming growth factor-β1 in mesenchymal cells is mediated by p38 MAPK-dependent induction of an … JC Horowitz, DY Lee, M Waghray, VG Keshamouni, PE Thomas, H Zhang, ... Journal of Biological Chemistry 279 (2), 1359-1367, 2004 | 305 | 2004 |
Combinatorial activation of FAK and AKT by transforming growth factor-β1 confers an anoikis-resistant phenotype to myofibroblasts JC Horowitz, DS Rogers, V Sharma, R Vittal, ES White, Z Cui, ... Cellular signalling 19 (4), 761-771, 2007 | 290 | 2007 |
Extracellular matrix in lung development, homeostasis and disease Y Zhou, JC Horowitz, A Naba, N Ambalavanan, K Atabai, J Balestrini, ... Matrix Biology 73, 77-104, 2018 | 263 | 2018 |
Future directions in idiopathic pulmonary fibrosis research. An NHLBI workshop report TS Blackwell, AM Tager, Z Borok, BB Moore, DA Schwartz, KJ Anstrom, ... American journal of respiratory and critical care medicine 189 (2), 214-222, 2014 | 249 | 2014 |
Endothelin-1 and transforming growth factor-β1 independently induce fibroblast resistance to apoptosis via AKT activation P Kulasekaran, CA Scavone, DS Rogers, DA Arenberg, VJ Thannickal, ... American journal of respiratory cell and molecular biology 41 (4), 484-493, 2009 | 183 | 2009 |
Matrix stiffness corresponding to strictured bowel induces a fibrogenic response in human colonic fibroblasts LA Johnson, ES Rodansky, KL Sauder, JC Horowitz, JD Mih, ... Inflammatory bowel diseases 19 (5), 891-903, 2013 | 180 | 2013 |
Inhibition of myocardin-related transcription factor/serum response factor signaling decreases lung fibrosis and promotes mesenchymal cell apoptosis TH Sisson, IO Ajayi, N Subbotina, AE Dodi, ES Rodansky, LN Chibucos, ... The American journal of pathology 185 (4), 969-986, 2015 | 172 | 2015 |
Prostaglandin E2 induces fibroblast apoptosis by modulating multiple survival pathways SK Huang, ES White, SH Wettlaufer, H Grifka, CM Hogaboam, ... The FASEB Journal 23 (12), 4317, 2009 | 164 | 2009 |
Epithelial-mesenchymal interactions in pulmonary fibrosis JC Horowitz, VJ Thannickal Seminars in respiratory and critical care medicine 27 (06), 600-612, 2006 | 160 | 2006 |
Modulation of prosurvival signaling in fibroblasts by a protein kinase inhibitor protects against fibrotic tissue injury R Vittal, JC Horowitz, BB Moore, H Zhang, FJ Martinez, GB Toews, ... The American journal of pathology 166 (2), 367-375, 2005 | 159 | 2005 |
Histone modifications are responsible for decreased Fas expression and apoptosis resistance in fibrotic lung fibroblasts SK Huang, AM Scruggs, J Donaghy, JC Horowitz, Z Zaslona, ... Cell death & disease 4 (5), e621-e621, 2013 | 151 | 2013 |
Plasminogen activation–induced pericellular fibronectin proteolysis promotes fibroblast apoptosis JC Horowitz, DS Rogers, RH Simon, TH Sisson, VJ Thannickal American journal of respiratory cell and molecular biology 38 (1), 78-87, 2008 | 142 | 2008 |
Update on the features and measurements of experimental acute lung injury in animals: an official American Thoracic Society workshop report HS Kulkarni, JS Lee, JA Bastarache, WM Kuebler, GP Downey, ... American journal of respiratory cell and molecular biology 66 (2), e1-e14, 2022 | 120 | 2022 |