| Astrocyte senescence as a component of Alzheimer’s disease R Bhat, EP Crowe, A Bitto, M Moh, CD Katsetos, FU Garcia, FB Johnson, ... Public Library of Science 7 (9), e45069, 2012 | 578 | 2012 |
| Transient rapamycin treatment can increase lifespan and healthspan in middle-aged mice A Bitto, TK Ito, VV Pineda, NJ LeTexier, HZ Huang, E Sutlief, H Tung, ... elife 5, e16351, 2016 | 419 | 2016 |
| Stress-induced senescence in human and rodent astrocytes A Bitto, C Sell, E Crowe, A Lorenzini, M Malaguti, S Hrelia, C Torres Experimental cell research 316 (17), 2961-2968, 2010 | 214 | 2010 |
| P62/SQSTM1 at the interface of aging, autophagy, and disease A Bitto, CA Lerner, T Nacarelli, E Crowe, C Torres, C Sell Age 36, 1123-1137, 2014 | 162 | 2014 |
| Functional mitochondria are required for α-synuclein toxicity in aging yeast S Buttner, A Bitto, J Ring, M Augsten, P Zabrocki, T Eisenberg, ... Journal of Biological Chemistry 283 (12), 7554-7560, 2008 | 162 | 2008 |
| Reduced mammalian target of rapamycin activity facilitates mitochondrial retrograde signaling and increases life span in normal human fibroblasts C Lerner, A Bitto, D Pulliam, T Nacarelli, M Konigsberg, H Van Remmen, ... Aging cell 12 (6), 966-977, 2013 | 136 | 2013 |
| Biochemical genetic pathways that modulate aging in multiple species A Bitto, AM Wang, CF Bennett, M Kaeberlein Cold Spring Harbor perspectives in medicine 5 (11), a025114, 2015 | 127 | 2015 |
| Antiaging diets: Separating fact from fiction MB Lee, CM Hill, A Bitto, M Kaeberlein Science 374 (6570), eabe7365, 2021 | 104 | 2021 |
| Dose-dependent effects of mTOR inhibition on weight and mitochondrial disease in mice SC Johnson, ME Yanos, A Bitto, A Castanza, A Gagnidze, B Gonzalez, ... Frontiers in genetics 6, 247, 2015 | 96 | 2015 |
| Proepithelin regulates prostate cancer cell biology by promoting cell growth, migration, and anchorage-independent growth G Monami, V Emiliozzi, A Bitto, F Lovat, SQ Xu, S Goldoni, M Fassan, ... The American journal of pathology 174 (3), 1037-1047, 2009 | 91 | 2009 |
| 17‐a‐estradiol late in life extends lifespan in aging UM‐HET3 male mice; nicotinamide riboside and three other drugs do not affect lifespan in either sex DE Harrison, R Strong, P Reifsnyder, N Kumar, E Fernandez, K Flurkey, ... Aging cell 20 (5), e13328, 2021 | 70 | 2021 |
| Long-term IGF-I exposure decreases autophagy and cell viability A Bitto, C Lerner, C Torres, M Roell, M Malaguti, V Perez, A Lorenzini, ... PloS one 5 (9), e12592, 2010 | 60 | 2010 |
| Transaldolase inhibition impairs mitochondrial respiration and induces a starvation-like longevity response in Caenorhabditis elegans CF Bennett, JJ Kwon, C Chen, J Russell, K Acosta, N Burnaevskiy, ... PLoS genetics 13 (3), e1006695, 2017 | 52 | 2017 |
| SS‐31 and NMN: Two paths to improve metabolism and function in aged hearts JA Whitson, A Bitto, H Zhang, MT Sweetwyne, R Coig, S Bhayana, ... Aging Cell 19 (10), e13213, 2020 | 50 | 2020 |
| Proepithelin is an autocrine growth factor for bladder cancer F Lovat, A Bitto, SQ Xu, M Fassan, S Goldoni, D Metalli, V Wubah, ... Carcinogenesis 30 (5), 861-868, 2009 | 47 | 2009 |
| mTOR inhibitors may benefit kidney transplant recipients with mitochondrial diseases SC Johnson, F Martinez, A Bitto, B Gonzalez, C Tazaerslan, C Cohen, ... Kidney international 95 (2), 455-466, 2019 | 46 | 2019 |
| Rejuvenation: it’s in our blood A Bitto, M Kaeberlein Cell metabolism 20 (1), 2-4, 2014 | 46 | 2014 |
| Regional metabolic signatures in the Ndufs4 (KO) mouse brain implicate defective glutamate/α-ketoglutarate metabolism in mitochondrial disease SC Johnson, EB Kayser, R Bornstein, J Stokes, A Bitto, KY Park, A Pan, ... Molecular genetics and metabolism 130 (2), 118-132, 2020 | 41 | 2020 |
| Design, Synthesis, and Biological Evaluation of Levoglucosenone‐Derived Ras Activation Inhibitors C Müller, MA Gomez‐Zurita Frau, D Ballinari, S Colombo, A Bitto, ... ChemMedChem: Chemistry Enabling Drug Discovery 4 (4), 524-528, 2009 | 36 | 2009 |
| Hepatic S6K1 partially regulates lifespan of mice with mitochondrial complex I deficiency TK Ito, C Lu, J Khan, Q Nguyen, HZ Huang, D Kim, J Phillips, J Tan, Y Lee, ... Frontiers in genetics 8, 113, 2017 | 24 | 2017 |
