| A new glucagon and GLP-1 co-agonist eliminates obesity in rodents JW Day, N Ottaway, JT Patterson, V Gelfanov, D Smiley, J Gidda, ... Nature chemical biology 5 (10), 749-757, 2009 | 690 | 2009 |
| Unimolecular dual incretins maximize metabolic benefits in rodents, monkeys, and humans B Finan, T Ma, N Ottaway, TD Müller, KM Habegger, KM Heppner, ... Science translational medicine 5 (209), 209ra151-209ra151, 2013 | 620 | 2013 |
| A rationally designed monomeric peptide triagonist corrects obesity and diabetes in rodents B Finan, B Yang, N Ottaway, DL Smiley, T Ma, C Clemmensen, ... Nature medicine 21 (1), 27-36, 2015 | 618 | 2015 |
| Paclitaxel sensitivity of breast cancer cells with constitutively active NF-κB is enhanced by IκBα super-repressor and parthenolide NM Patel, S Nozaki, NH Shortle, P Bhat-Nakshatri, TR Newton, S Rice, ... Oncogene 19 (36), 4159-4169, 2000 | 375 | 2000 |
| Targeted estrogen delivery reverses the metabolic syndrome B Finan, B Yang, N Ottaway, K Stemmer, TD Müller, CX Yi, K Habegger, ... Nature medicine 18 (12), 1847-1856, 2012 | 293 | 2012 |
| Fibroblast growth factor 21 mediates specific glucagon actions KM Habegger, K Stemmer, C Cheng, TD Müller, KM Heppner, N Ottaway, ... Diabetes 62 (5), 1453-1463, 2013 | 250 | 2013 |
| Unimolecular polypharmacy for treatment of diabetes and obesity MH Tschöp, B Finan, C Clemmensen, V Gelfanov, D Perez-Tilve, ... Cell metabolism 24 (1), 51-62, 2016 | 230 | 2016 |
| Chemical hybridization of glucagon and thyroid hormone optimizes therapeutic impact for metabolic disease B Finan, C Clemmensen, Z Zhu, K Stemmer, K Gauthier, L Müller, ... Cell 167 (3), 843-857. e14, 2016 | 184 | 2016 |
| Optimized GIP analogs promote body weight lowering in mice through GIPR agonism not antagonism PA Mroz, B Finan, V Gelfanov, B Yang, MH Tschöp, RD DiMarchi, ... Molecular Metabolism 20, 51-62, 2019 | 157 | 2019 |
| Optimization of co‐agonism at GLP‐1 and glucagon receptors to safely maximize weight reduction in DIO‐rodents JW Day, V Gelfanov, D Smiley, PE Carrington, G Eiermann, G Chicchi, ... Peptide Science 98 (5), 443-450, 2012 | 144 | 2012 |
| Peptide lipidation stabilizes structure to enhance biological function BP Ward, NL Ottaway, D Perez-Tilve, D Ma, VM Gelfanov, MH Tschöp, ... Molecular metabolism 2 (4), 468-479, 2013 | 119 | 2013 |
| Glucagon regulation of energy metabolism KM Heppner, KM Habegger, J Day, PT Pfluger, D Perez-Tilve, B Ward, ... Physiology & behavior 100 (5), 545-548, 2010 | 93 | 2010 |
| Role for c-jun N-terminal kinase in treatment-refractory acute myeloid leukemia (AML): signaling to multidrug-efflux and hyperproliferation LD Cripe, VM Gelfanov, EA Smith, DR Spigel, CA Phillips, TG Gabig, ... Leukemia 16 (5), 799-812, 2002 | 83 | 2002 |
| Viral insulin-like peptides activate human insulin and IGF-1 receptor signaling: A paradigm shift for host–microbe interactions E Altindis, W Cai, M Sakaguchi, F Zhang, W GuoXiao, F Liu, P De Meyts, ... Proceedings of the National Academy of Sciences 115 (10), 2461-2466, 2018 | 79 | 2018 |
| Optimization of the native glucagon sequence for medicinal purposes JR Chabenne, MA DiMarchi, VM Gelfanov, RD DiMarchi Journal of diabetes science and technology 4 (6), 1322-1331, 2010 | 71 | 2010 |
| A glucagon analog chemically stabilized for immediate treatment of life-threatening hypoglycemia J Chabenne, MDM Chabenne, Y Zhao, J Levy, D Smiley, V Gelfanov, ... Molecular Metabolism 3 (3), 293-300, 2014 | 61 | 2014 |
| A novel human-based receptor antagonist of sustained action reveals body weight control by endogenous GLP-1 JT Patterson, N Ottaway, VM Gelfanov, DL Smiley, D Perez-Tilve, ... ACS Chemical Biology 6 (2), 135-145, 2011 | 58 | 2011 |
| Transformation of interleukin-3–dependent cells without participation of Stat5/bcl-xL: cooperation of akt with raf/erk leads to p65 nuclear factor κB–mediated antiapoptosis … VM Gelfanov, GS Burgess, S Litz-Jackson, AJ King, MS Marshall, ... Blood, The Journal of the American Society of Hematology 98 (8), 2508-2517, 2001 | 55 | 2001 |
| Chemical synthesis of insulin analogs through a novel precursor AN Zaykov, JP Mayer, VM Gelfanov, RD DiMarchi ACS Chemical Biology 9 (3), 683-691, 2014 | 47 | 2014 |
| Synthesis of four-disulfide insulin analogs via sequential disulfide bond formation F Wu, JP Mayer, VM Gelfanov, F Liu, RD DiMarchi The Journal of Organic Chemistry 82 (7), 3506-3512, 2017 | 33 | 2017 |
