| α-synuclein oligomers interact with ATP synthase and open the permeability transition pore in Parkinson’s disease MHR Ludtmann, PR Angelova, MH Horrocks, ML Choi, M Rodrigues, ... Nature communications 9 (1), 2293, 2018 | 448 | 2018 |
| Alpha-synuclein oligomers interact with metal ions to induce oxidative stress and neuronal death in Parkinson's disease E Deas, N Cremades, PR Angelova, MHR Ludtmann, Z Yao, S Chen, ... Antioxidants & redox signaling 24 (7), 376-391, 2016 | 353 | 2016 |
| Impaired mitochondrial calcium efflux contributes to disease progression in models of Alzheimer’s disease P Jadiya, DW Kolmetzky, D Tomar, A Di Meco, AA Lombardi, JP Lambert, ... Nature communications 10 (1), 3885, 2019 | 261 | 2019 |
| Nrf2 affects the efficiency of mitochondrial fatty acid oxidation MHR Ludtmann, PR Angelova, Y Zhang, AY Abramov, ... Biochemical Journal 457 (3), 415-424, 2014 | 250 | 2014 |
| Ca2+ is a key factor in α-synuclein-induced neurotoxicity PR Angelova, MHR Ludtmann, MH Horrocks, A Negoda, N Cremades, ... Journal of cell science 129 (9), 1792-1801, 2016 | 198 | 2016 |
| Aggregated α-synuclein and complex I deficiency: exploration of their relationship in differentiated neurons AK Reeve, MHR Ludtmann, PR Angelova, EM Simcox, MH Horrocks, ... Cell death & disease 6 (7), e1820-e1820, 2015 | 187 | 2015 |
| Monomeric alpha-synuclein exerts a physiological role on brain ATP synthase MHR Ludtmann, PR Angelova, NN Ninkina, S Gandhi, VL Buchman, ... Journal of Neuroscience 36 (41), 10510-10521, 2016 | 177 | 2016 |
| PKA phosphorylation of NCLX reverses mitochondrial calcium overload and depolarization, promoting survival of PINK1-deficient dopaminergic neurons M Kostic, MHR Ludtmann, H Bading, M Hershfinkel, E Steer, CT Chu, ... Cell reports 13 (2), 376-386, 2015 | 174 | 2015 |
| Loss of PINK1 increases the heart's vulnerability to ischemia-reperfusion injury HK Siddall, DM Yellon, SB Ong, UA Mukherjee, N Burke, AR Hall, ... PloS one 8 (4), e62400, 2013 | 144 | 2013 |
| A missense mutation in KCTD17 causes autosomal dominant myoclonus-dystonia NE Mencacci, I Rubio-Agusti, A Zdebik, F Asmus, MHR Ludtmann, ... The American Journal of Human Genetics 96 (6), 938-947, 2015 | 138 | 2015 |
| Mitochondrial calcium imbalance in Parkinson’s disease MHR Ludtmann, AY Abramov Neuroscience letters 663, 86-90, 2018 | 124 | 2018 |
| LRRK2 deficiency induced mitochondrial Ca2+ efflux inhibition can be rescued by Na+/Ca2+/Li+ exchanger upregulation MHR Ludtmann, M Kostic, A Horne, S Gandhi, I Sekler, AY Abramov Cell death & disease 10 (4), 265, 2019 | 113* | 2019 |
| Hypoxia signaling controls postnatal changes in cardiac mitochondrial morphology and function MT Neary, KE Ng, MHR Ludtmann, AR Hall, I Piotrowska, SB Ong, ... Journal of molecular and cellular cardiology 74, 340-352, 2014 | 102 | 2014 |
| Clinical, pathological and functional characterization of riboflavin-responsive neuropathy A Manole, Z Jaunmuktane, I Hargreaves, MHR Ludtmann, V Salpietro, ... Brain 140 (11), 2820-2837, 2017 | 84 | 2017 |
| Nanobodies raised against monomeric ɑ-synuclein inhibit fibril formation and destabilize toxic oligomeric species M Iljina, L Hong, MH Horrocks, MH Ludtmann, ML Choi, CD Hughes, ... BMC biology 15, 1-14, 2017 | 76 | 2017 |
| FBS/BSA media concentration determines CCCP’s ability to depolarize mitochondria and activate PINK1-PRKN mitophagy MPM Soutar, L Kempthorne, E Annuario, C Luft, S Wray, R Ketteler, ... Autophagy 15 (11), 2002-2011, 2019 | 72 | 2019 |
| Molecular pharmacology in a simple model system: implicating MAP kinase and phosphoinositide signalling in bipolar disorder MHR Ludtmann, K Boeckeler, RSB Williams Seminars in cell & developmental biology 22 (1), 105-113, 2011 | 55 | 2011 |
| Naringenin inhibits the growth of Dictyostelium and MDCK‐derived cysts in a TRPP2 (polycystin‐2)‐dependent manner A Waheed, MHR Ludtmann, N Pakes, S Robery, A Kuspa, C Dinh, ... British Journal of Pharmacology 171 (10), 2659-2670, 2014 | 48 | 2014 |
| Mutations in valosin-containing protein (VCP) decrease ADP/ATP translocation across the mitochondrial membrane and impair energy metabolism in human neurons MHR Ludtmann, C Arber, F Bartolome, M de Vicente, E Preza, E Carro, ... Journal of Biological Chemistry 292 (21), 8907-8917, 2017 | 41 | 2017 |
| An ancestral non-proteolytic role for presenilin proteins in multicellular development of the social amoeba Dictyostelium discoideum MHR Ludtmann, GP Otto, C Schilde, ZH Chen, CY Allan, S Brace, ... Journal of cell science 127 (7), 1576-1584, 2014 | 35 | 2014 |
