Stimulation of the sigma-1 receptor by DHEA enhances synaptic efficacy and neurogenesis in the hippocampal dentate gyrus of olfactory bulbectomized mice S Moriguchi, Y Shinoda, Y Yamamoto, Y Sasaki, K Miyajima, H Tagashira, ... PLoS One 8 (4), e60863, 2013 | 99 | 2013 |
Methyl pyruvate rescues mitochondrial damage caused by SIGMAR1 mutation related to amyotrophic lateral sclerosis H Tagashira, Y Shinoda, N Shioda, K Fukunaga Biochimica et Biophysica Acta (BBA)-General Subjects 1840 (12), 3320-3334, 2014 | 67 | 2014 |
The role of SIGMAR1 gene mutation and mitochondrial dysfunction in amyotrophic lateral sclerosis K Fukunaga, Y Shinoda, H Tagashira Journal of pharmacological sciences 127 (1), 36-41, 2015 | 64 | 2015 |
trans-Fatty acids promote proinflammatory signaling and cell death by stimulating the apoptosis signal-regulating kinase 1 (ASK1)-p38 pathway Y Hirata, M Takahashi, Y Kudoh, K Kano, H Kawana, K Makide, ... Journal of Biological Chemistry 292 (20), 8174-8185, 2017 | 57 | 2017 |
Development of FABP3 ligands that inhibit arachidonic acid-induced α-synuclein oligomerization A Cheng, Y Shinoda, T Yamamoto, H Miyachi, K Fukunaga Brain research 1707, 190-197, 2019 | 48 | 2019 |
Dehydroepiandrosterone administration improves memory deficits following transient brain ischemia through sigma-1 receptor stimulation Y Yabuki, Y Shinoda, H Izumi, T Ikuno, N Shioda, K Fukunaga Brain research 1622, 102-113, 2015 | 39 | 2015 |
Acyl-CoA binding domain containing 3 (ACBD3) recruits the protein phosphatase PPM1L to ER–Golgi membrane contact sites Y Shinoda, K Fujita, S Saito, H Matsui, Y Kanto, Y Nagaura, K Fukunaga, ... FEBS letters 586 (19), 3024-3029, 2012 | 38 | 2012 |
Haloperidol aggravates transverse aortic constriction-induced heart failure via mitochondrial dysfunction Y Shinoda, H Tagashira, MS Bhuiyan, H Hasegawa, H Kanai, ... Journal of pharmacological sciences 131 (3), 172-183, 2016 | 33 | 2016 |
Analysis of binding affinity and docking of novel fatty acid-binding protein (FABP) ligands Y Shinoda, Y Wang, T Yamamoto, H Miyachi, K Fukunaga Journal of pharmacological sciences 143 (4), 264-271, 2020 | 31 | 2020 |
Crucial role of dopamine D2 receptor signaling in nicotine-induced conditioned place preference G Wilar, Y Shinoda, T Sasaoka, K Fukunaga Molecular neurobiology 56 (12), 7911-7928, 2019 | 26 | 2019 |
The disease-modifying drug candidate, SAK3 improves cognitive impairment and inhibits amyloid beta deposition in app knock-in mice H Izumi, Y Shinoda, T Saito, TC Saido, K Sato, Y Yabuki, Y Matsumoto, ... Neuroscience 377, 87-97, 2018 | 26 | 2018 |
Neuroprotective effects of protein tyrosine phosphatase 1B inhibitor on cerebral ischemia/reperfusion in mice M Sun, H Izumi, Y Shinoda, K Fukunaga Brain research 1694, 1-12, 2018 | 25 | 2018 |
KY-226 protects blood–brain barrier function through the Akt/FoxO1 signaling pathway in brain ischemia M Sun, Y Shinoda, K Fukunaga Neuroscience 399, 89-102, 2019 | 24 | 2019 |
Epidermal fatty acid-binding protein 5 (FABP5) Involvement in alpha-synuclein-induced mitochondrial injury under oxidative stress Y Wang, Y Shinoda, A Cheng, I Kawahata, K Fukunaga Biomedicines 9 (2), 110, 2021 | 20 | 2021 |
Ouabagenin is a naturally occurring LXR ligand without causing hepatic steatosis as a side effect S Tamura, M Okada, S Kato, Y Shinoda, N Shioda, K Fukunaga, K Ui-Tei, ... Scientific reports 8 (1), 2305, 2018 | 19 | 2018 |
Novel fatty acid-binding protein 3 ligand inhibits dopaminergic neuronal death and improves motor and cognitive impairments in Parkinson's disease model mice H Haga, R Yamada, H Izumi, Y Shinoda, I Kawahata, H Miyachi, ... Pharmacology Biochemistry and Behavior 191, 172891, 2020 | 18 | 2020 |
Combined citicoline and docosahexaenoic acid treatment improves cognitive dysfunction following transient brain ischemia E Nakazaki, Y Yabuki, H Izumi, Y Shinoda, F Watanabe, Y Hishida, ... Journal of pharmacological sciences 139 (4), 319-324, 2019 | 17 | 2019 |
Alzheimer's disease therapeutic candidate SAK3 is an enhancer of T-type calcium channels K Fukunaga, H Izumi, Y Yabuki, Y Shinoda, N Shioda, F Han Journal of pharmacological sciences 139 (2), 51-58, 2019 | 17 | 2019 |
Ligand bound fatty acid binding protein 7 (FABP7) drives melanoma cell proliferation via modulation of Wnt/β-catenin signaling BA Umaru, Y Kagawa, SK Shil, N Arakawa, Y Pan, H Miyazaki, ... Pharmaceutical Research 38, 479-490, 2021 | 16 | 2021 |
Combined memantine and donepezil treatment improves behavioral and psychological symptoms of dementia-like behaviors in olfactory bulbectomized mice Y Yabuki, K Matsuo, K Hirano, Y Shinoda, S Moriguchi, K Fukunaga Pharmacology 99 (3-4), 160-171, 2017 | 16 | 2017 |