Large-scale exome sequencing study implicates both developmental and functional changes in the neurobiology of autism FK Satterstrom, JA Kosmicki, J Wang, MS Breen, S De Rubeis, JY An, ... Cell 180 (3), 568-584. e23, 2020 | 1742 | 2020 |
Dynamic changes in the copy number of pluripotency and cell proliferation genes in human ESCs and iPSCs during reprogramming and time in culture LC Laurent, I Ulitsky, I Slavin, H Tran, A Schork, R Morey, C Lynch, ... Cell stem cell 8 (1), 106-118, 2011 | 1030 | 2011 |
Shared molecular neuropathology across major psychiatric disorders parallels polygenic overlap MJ Gandal, JR Haney, NN Parikshak, V Leppa, G Ramaswami, C Hartl, ... Science 359 (6376), 693-697, 2018 | 983 | 2018 |
Subcortical brain volume differences in participants with attention deficit hyperactivity disorder in children and adults: a cross-sectional mega-analysis M Hoogman, J Bralten, DP Hibar, M Mennes, MP Zwiers, LSJ Schweren, ... The Lancet Psychiatry 4 (4), 310-319, 2017 | 943 | 2017 |
Common genetic variants influence human subcortical brain structures DP Hibar, JL Stein, ME Renteria, A Arias-Vasquez, S Desrivières, ... Nature 520 (7546), 224-229, 2015 | 842 | 2015 |
The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data PM Thompson, JL Stein, SE Medland, DP Hibar, AA Vasquez, ... Brain imaging and behavior 8, 153-182, 2014 | 668 | 2014 |
Exploring comorbidity within mental disorders among a Danish national population O Plana-Ripoll, CB Pedersen, Y Holtz, ME Benros, S Dalsgaard, ... JAMA psychiatry 76 (3), 259-270, 2019 | 537 | 2019 |
Improved detection of common variants associated with schizophrenia by leveraging pleiotropy with cardiovascular-disease risk factors OA Andreassen, S Djurovic, WK Thompson, AJ Schork, KS Kendler, ... The American Journal of Human Genetics 92 (2), 197-209, 2013 | 486 | 2013 |
Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis JZ Liu, JR Hov, T Folseraas, E Ellinghaus, SM Rushbrook, NT Doncheva, ... Nature genetics 45 (6), 670-675, 2013 | 433 | 2013 |
Genome-wide analyses for personality traits identify six genomic loci and show correlations with psychiatric disorders MT Lo, DA Hinds, JY Tung, C Franz, CC Fan, Y Wang, OB Smeland, ... Nature genetics 49 (1), 152-156, 2017 | 415 | 2017 |
Genetic assessment of age-associated Alzheimer disease risk: development and validation of a polygenic hazard score RS Desikan, CC Fan, Y Wang, AJ Schork, HJ Cabral, LA Cupples, ... PLoS medicine 14 (3), e1002258, 2017 | 397 | 2017 |
Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals L Folkersen, S Gustafsson, Q Wang, DH Hansen, ÅK Hedman, A Schork, ... Nature metabolism 2 (10), 1135-1148, 2020 | 383 | 2020 |
Association between mental disorders and subsequent medical conditions NC Momen, O Plana-Ripoll, E Agerbo, ME Benros, AD Børglum, ... New England Journal of Medicine 382 (18), 1721-1731, 2020 | 348 | 2020 |
Improved detection of common variants associated with schizophrenia and bipolar disorder using pleiotropy-informed conditional false discovery rate OA Andreassen, WK Thompson, AJ Schork, S Ripke, M Mattingsdal, ... PLoS genetics 9 (4), e1003455, 2013 | 344 | 2013 |
Genetic correlations of polygenic disease traits: from theory to practice W Van Rheenen, WJ Peyrot, AJ Schork, SH Lee, NR Wray Nature Reviews Genetics 20 (10), 567-581, 2019 | 333 | 2019 |
All SNPs are not created equal: genome-wide association studies reveal a consistent pattern of enrichment among functionally annotated SNPs AJ Schork, WK Thompson, P Pham, A Torkamani, JC Roddey, PF Sullivan, ... PLoS genetics 9 (4), e1003449, 2013 | 326 | 2013 |
Novel genetic loci associated with hippocampal volume DP Hibar, HHH Adams, N Jahanshad, G Chauhan, JL Stein, E Hofer, ... Nature communications 8 (1), 13624, 2017 | 305 | 2017 |
Meta-analysis identifies five novel loci associated with endometriosis highlighting key genes involved in hormone metabolism Y Sapkota, V Steinthorsdottir, AP Morris, A Fassbender, N Rahmioglu, ... Nature communications 8 (1), 15539, 2017 | 295 | 2017 |
Genome-wide pleiotropy between Parkinson disease and autoimmune diseases A Witoelar, IE Jansen, Y Wang, RS Desikan, JR Gibbs, C Blauwendraat, ... JAMA neurology 74 (7), 780-792, 2017 | 275 | 2017 |
Novel genetic loci underlying human intracranial volume identified through genome-wide association HHH Adams, DP Hibar, V Chouraki, JL Stein, PA Nyquist, ME Rentería, ... Nature neuroscience 19 (12), 1569-1582, 2016 | 247 | 2016 |