Roles of Lsr2 in Colony Morphology and Biofilm Formation of Mycobacterium smegmatis JM Chen, GJ German, DC Alexander, H Ren, T Tan, J Liu Journal of bacteriology 188 (2), 633-641, 2006 | 174 | 2006 |
Virulence Regulator EspR of Mycobacterium tuberculosis Is a Nucleoid-Associated Protein B Blasco, JM Chen, R Hartkoorn, C Sala, S Uplekar, J Rougemont, ... PLoS pathogens 8 (3), e1002621, 2012 | 153 | 2012 |
Lsr2 of Mycobacterium tuberculosis is a DNA-bridging protein JM Chen, H Ren, JE Shaw, YJ Wang, M Li, AS Leung, V Tran, ... Nucleic acids research 36 (7), 2123-2135, 2008 | 122 | 2008 |
Identification of the lipooligosaccharide biosynthetic gene cluster from Mycobacterium marinum H Ren, LG Dover, ST Islam, DC Alexander, JM Chen, GS Besra, J Liu Molecular microbiology 63 (5), 1345-1359, 2007 | 113 | 2007 |
Anticytolytic screen identifies inhibitors of mycobacterial virulence protein secretion J Rybniker, JM Chen, C Sala, RC Hartkoorn, A Vocat, A Benjak, ... Cell Host & Microbe 16 (4), 538-548, 2014 | 104 | 2014 |
EspD is critical for the virulence-mediating ESX-1 secretion system in Mycobacterium tuberculosis JM Chen, S Boy-Röttger, N Dhar, N Sweeney, RS Buxton, F Pojer, ... Journal of bacteriology 194 (4), 884-893, 2012 | 102 | 2012 |
ESAT-6 Secretion-Independent Impact of ESX-1 Genes espF and espG1 on Virulence of Mycobacterium tuberculosis D Bottai, L Majlessi, R Simeone, W Frigui, C Laurent, P Lenormand, ... Journal of Infectious Diseases 203 (8), 1155-1164, 2011 | 92 | 2011 |
Differential productions of lipid virulence factors among BCG vaccine strains and implications on BCG safety JM Chen, ST Islam, H Ren, J Liu Vaccine 25 (48), 8114-8122, 2007 | 88 | 2007 |
Mycobacterium tuberculosis EspB binds phospholipids and mediates EsxA‐independent virulence JM Chen, M Zhang, J Rybniker, S Boy‐Röttger, N Dhar, F Pojer, ST Cole Molecular microbiology 89 (6), 1154-1166, 2013 | 77 | 2013 |
A Point Mutation in cycA Partially Contributes to the D-cycloserine Resistance Trait of Mycobacterium bovis BCG Vaccine Strains JM Chen, S Uplekar, SV Gordon, ST Cole Public Library of Science 7 (8), e43467, 2012 | 76 | 2012 |
PimF, a mannosyltransferase of mycobacteria, is involved in the biosynthesis of phosphatidylinositol mannosides and lipoarabinomannan DC Alexander, JRW Jones, T Tan, JM Chen, J Liu Journal of Biological Chemistry 279 (18), 18824-18833, 2004 | 69 | 2004 |
Mycobacterium bovis BCG Vaccines Exhibit Defects in Alanine and Serine Catabolism JM Chen, DC Alexander, MA Behr, J Liu Infection and immunity 71 (2), 708-716, 2003 | 68 | 2003 |
Site-directed mutagenesis of acyl carrier protein (ACP) reveals amino acid residues involved in ACP structure and acyl-ACP synthetase activity AS Flaman, JM Chen, SC Van Iderstine, DM Byers Journal of Biological Chemistry 276 (38), 35934-35939, 2001 | 61 | 2001 |
Phenotypic Profiling of Mycobacterium tuberculosis EspA Point Mutants Reveals that Blockage of ESAT-6 and CFP-10 Secretion In Vitro Does Not Always Correlate … JM Chen, M Zhang, J Rybniker, L Basterra, N Dhar, AD Tischler, F Pojer, ... Journal of bacteriology 195 (24), 5421-5430, 2013 | 60 | 2013 |
The cysteine desulfurase IscS of Mycobacterium tuberculosis is involved in iron-sulfur cluster biogenesis and oxidative stress defence J Rybniker, F Pojer, J Marienhagen, GS Kolly, JM Chen, E van Gumpel, ... Biochemical journal 459 (3), 467-478, 2014 | 50 | 2014 |
EspI regulates the ESX-1 secretion system in response to ATP levels in Mycobacterium tuberculosis M Zhang, JM Chen, C Sala, J Rybniker, N Dhar, ST Cole Molecular microbiology 93 (5), 1057-1065, 2014 | 31 | 2014 |
Towards anti-virulence drugs targeting ESX-1 mediated pathogenesis of Mycobacterium tuberculosis JM Chen, F Pojer, B Blasco, ST Cole Drug Discovery Today: Disease Mechanisms 7 (1), e25-e31, 2010 | 27 | 2010 |
Sigma Factor F Does Not Prevent Rifampin Inhibition of RNA Polymerase or Cause Rifampin Tolerance in Mycobacterium tuberculosis RC Hartkoorn, C Sala, SJ Magnet, JM Chen, F Pojer, ST Cole Journal of bacteriology 192 (20), 5472-5479, 2010 | 20 | 2010 |
Mycobacterium tuberculosis EspK has active but distinct roles in the secretion of EsxA and EspB ZL Lim, K Drever, N Dhar, ST Cole, JM Chen Journal of Bacteriology 204 (4), e00060-22, 2022 | 12 | 2022 |
Mycosins of the mycobacterial type VII ESX secretion system: the glue that holds the party together JM Chen Mbio 7 (6), 10.1128/mbio. 02062-16, 2016 | 7 | 2016 |