Obesity, metabolic dysfunction, and cardiac fibrosis: pathophysiological pathways, molecular mechanisms, and therapeutic opportunities M Cavalera, J Wang, NG Frangogiannis Translational Research 164 (4), 323-335, 2014 | 283 | 2014 |
Thrombospondin-1 induction in the diabetic myocardium stabilizes the cardiac matrix in addition to promoting vascular rarefaction through angiopoietin-2 upregulation C Gonzalez-Quesada, M Cavalera, A Biernacka, P Kong, DW Lee, ... Circulation research 113 (12), 1331-1344, 2013 | 137 | 2013 |
Protective effects of activated myofibroblasts in the pressure-overloaded myocardium are mediated through smad-dependent activation of a matrix-preserving program I Russo, M Cavalera, S Huang, Y Su, A Hanna, B Chen, AV Shinde, ... Circulation research 124 (8), 1214-1227, 2019 | 111 | 2019 |
Smad3 signaling promotes fibrosis while preserving cardiac and aortic geometry in obese diabetic mice A Biernacka, M Cavalera, J Wang, I Russo, A Shinde, P Kong, ... Circulation: Heart Failure 8 (4), 788-798, 2015 | 111 | 2015 |
Loss of TIMP3 underlies diabetic nephropathy via FoxO1/STAT1 interplay L Fiorentino, M Cavalera, S Menini, V Marchetti, M Mavilio, M Fabrizi, ... EMBO molecular medicine 5 (3), 441-455, 2013 | 107 | 2013 |
Increased tumor necrosis factor α–converting enzyme activity induces insulin resistance and hepatosteatosis in mice L Fiorentino, A Vivanti, M Cavalera, V Marzano, M Ronci, M Fabrizi, ... Hepatology 51 (1), 103-110, 2010 | 106 | 2010 |
Regulation of TIMP3 in diabetic nephropathy: a role for microRNAs L Fiorentino, M Cavalera, M Mavilio, F Conserva, R Menghini, L Gesualdo, ... Acta diabetologica 50, 965-969, 2013 | 101 | 2013 |
Overexpression of tissue inhibitor of metalloproteinase 3 in macrophages reduces atherosclerosis in low-density lipoprotein receptor knockout mice V Casagrande, R Menghini, S Menini, A Marino, V Marchetti, M Cavalera, ... Arteriosclerosis, thrombosis, and vascular biology 32 (1), 74-81, 2012 | 100 | 2012 |
Thrombospondin-1 regulates adiposity and metabolic dysfunction in diet-induced obesity enhancing adipose inflammation and stimulating adipocyte proliferation P Kong, C Gonzalez-Quesada, N Li, M Cavalera, DW Lee, ... American Journal of Physiology-Endocrinology And Metabolism 305 (3), E439-E450, 2013 | 94 | 2013 |
Targeting the chemokines in cardiac repair M Cavalera, N G Frangogiannis Current pharmaceutical design 20 (12), 1971-1979, 2014 | 78 | 2014 |
IL-21 is a major negative regulator of IRF4-dependent lipolysis affecting Tregs in adipose tissue and systemic insulin sensitivity M Fabrizi, V Marchetti, M Mavilio, A Marino, V Casagrande, M Cavalera, ... Diabetes 63 (6), 2086-2096, 2014 | 58 | 2014 |
High levels of soluble lectinlike oxidized low‐density lipoprotein receptor‐1 are associated with carotid plaque inflammation and increased risk of ischemic stroke H Markstad, A Edsfeldt, I Yao Mattison, E Bengtsson, P Singh, M Cavalera, ... Journal of the American Heart Association 8 (4), e009874, 2019 | 53 | 2019 |
Loss of TIMP3 exacerbates atherosclerosis in ApoE null mice R Stöhr, M Cavalera, S Menini, M Mavilio, V Casagrande, C Rossi, ... Atherosclerosis 235 (2), 438-443, 2014 | 52 | 2014 |
The role of thrombospondin (TSP)-1 in obesity and diabetes P Kong, M Cavalera, NG Frangogiannis Adipocyte 3 (1), 81-84, 2014 | 51 | 2014 |
Tissue inhibitor of metalloproteinase-3 regulates inflammation in human and mouse intestine I Monteleone, M Federici, M Sarra, E Franzè, V Casagrande, F Zorzi, ... Gastroenterology 143 (5), 1277-1287. e4, 2012 | 46 | 2012 |
sTRAIL-R2 (soluble TNF [tumor necrosis factor]-related apoptosis-inducing ligand receptor 2) a marker of plaque cell apoptosis and cardiovascular events I Gonçalves, P Singh, C Tengryd, M Cavalera, I Yao Mattisson, ... Stroke 50 (8), 1989-1996, 2019 | 30 | 2019 |
TIMP3 interplays with apelin to regulate cardiovascular metabolism in hypercholesterolemic mice R Stöhr, BA Kappel, D Carnevale, M Cavalera, M Mavilio, I Arisi, ... Molecular metabolism 4 (10), 741-752, 2015 | 27 | 2015 |
Dietary rose hip exerts antiatherosclerotic effects and increases nitric oxide-mediated dilation in ApoE-null mice M Cavalera, U Axling, C Rippe, K Swärd, C Holm The Journal of nutritional biochemistry 44, 52-59, 2017 | 25 | 2017 |
Rose hip supplementation increases energy expenditure and induces browning of white adipose tissue M Cavalera, U Axling, K Berger, C Holm Nutrition & metabolism 13, 1-9, 2016 | 25 | 2016 |
Leptin deficiency reverses high metabolic state and weight loss without affecting central pathology in the R6/2 mouse model of Huntington's disease M Sjögren, R Soylu-Kucharz, U Dandunna, TL Stan, M Cavalera, ... Neurobiology of disease 132, 104560, 2019 | 17 | 2019 |