Rethinking dog domestication by integrating genetics, archeology, and biogeography G Larson, EK Karlsson, A Perri, MT Webster, SYW Ho, J Peters, PW Stahl, ... Proceedings of the National Academy of Sciences 109 (23), 8878-8883, 2012 | 648 | 2012 |
The dog as a cancer model C Khanna, K Lindblad-Toh, D Vail, C London, P Bergman, L Barber, ... Nature biotechnology 24 (9), 1065-1066, 2006 | 429 | 2006 |
Diagnosis of canine lymphoid neoplasia using clonal rearrangements of antigen receptor genes RC Burnett, W Vernau, JF Modiano, CS Olver, PF Moore, AC Avery Veterinary pathology 40 (1), 32-41, 2003 | 363 | 2003 |
Evolutionarily conserved cytogenetic changes in hematological malignancies of dogs and humans–man and his best friend share more than companionship M Breen, JF Modiano Chromosome Research 16, 145-154, 2008 | 265 | 2008 |
A Sleeping Beauty forward genetic screen identifies new genes and pathways driving osteosarcoma development and metastasis BS Moriarity, GM Otto, EP Rahrmann, SK Rathe, NK Wolf, MT Weg, ... Nature genetics 47 (6), 615-624, 2015 | 257 | 2015 |
Distinct B-cell and T-cell lymphoproliferative disease prevalence among dog breeds indicates heritable risk JF Modiano, M Breen, RC Burnett, HG Parker, S Inusah, R Thomas, ... Cancer research 65 (13), 5654-5661, 2005 | 241 | 2005 |
NFATc2-mediated repression of cyclin-dependent kinase 4 expression S Baksh, HR Widlund, AA Frazer-Abel, J Du, S Fosmire, DE Fisher, ... Molecular cell 10 (5), 1071-1081, 2002 | 210 | 2002 |
Artemisinin blocks prostate cancer growth and cell cycle progression by disrupting Sp1 interactions with the cyclin-dependent kinase-4 (CDK4) promoter and inhibiting CDK4 gene … JA Willoughby, SN Sundar, M Cheung, AS Tin, J Modiano, GL Firestone Journal of Biological Chemistry 284 (4), 2203-2213, 2009 | 193 | 2009 |
Canine lymphoma as a comparative model for human non-Hodgkin lymphoma: recent progress and applications D Ito, AM Frantz, JF Modiano Veterinary immunology and immunopathology 159 (3-4), 192-201, 2014 | 176 | 2014 |
Genome-wide analyses implicate 33 loci in heritable dog osteosarcoma, including regulatory variants near CDKN2A/B EK Karlsson, S Sigurdsson, E Ivansson, R Thomas, I Elvers, J Wright, ... Genome biology 14, 1-16, 2013 | 175 | 2013 |
Canine hemangiosarcoma originates from hematopoietic precursors with potential for endothelial differentiation AR Lamerato-Kozicki, KM Helm, CM Jubala, GC Cutter, JF Modiano Experimental hematology 34 (7), 870-878, 2006 | 163 | 2006 |
Perturbation of 14q32 miRNAs-cMYC gene network in osteosarcoma V Thayanithy, AL Sarver, RV Kartha, L Li, AY Angstadt, M Breen, CJ Steer, ... Bone 50 (1), 171-181, 2012 | 151 | 2012 |
CD20 expression in normal canine B cells and in canine non-Hodgkin lymphoma CM Jubala, JW Wojcieszyn, VEO Valli, DM Getzy, SP Fosmire, D Coffey, ... Veterinary pathology 42 (4), 468-476, 2005 | 146 | 2005 |
Expression and significance of p53, rb, p21/waf-1, p16/ink-4a, and PTEN tumor suppressors in canine melanoma A Koenig, SR Bianco, S Fosmire, J Wojcieszyn, JF Modiano Veterinary pathology 39 (4), 458-472, 2002 | 136 | 2002 |
The molecular basis of canine melanoma: pathogenesis and trends in diagnosis and therapy JF Modiano, MG Ritt, J Wojcieszyn Journal of Veterinary Internal Medicine 13 (3), 163-174, 1999 | 133 | 1999 |
Molecular profiling reveals prognostically significant subtypes of canine lymphoma AM Frantz, AL Sarver, D Ito, TL Phang, A Karimpour-Fard, MC Scott, ... Veterinary pathology 50 (4), 693-703, 2013 | 131 | 2013 |
Molecular subtypes of osteosarcoma identified by reducing tumor heterogeneity through an interspecies comparative approach MC Scott, AL Sarver, KJ Gavin, V Thayanithy, DM Getzy, RA Newman, ... Bone 49 (3), 356-367, 2011 | 126 | 2011 |
Canine cancer immunotherapy studies: linking mouse and human JS Park, SS Withers, JF Modiano, MS Kent, M Chen, JI Luna, WTN Culp, ... Journal for immunotherapy of cancer 4, 1-11, 2016 | 125 | 2016 |
Exome sequencing of lymphomas from three dog breeds reveals somatic mutation patterns reflecting genetic background I Elvers, J Turner-Maier, R Swofford, M Koltookian, J Johnson, C Stewart, ... Genome research 25 (11), 1634-1645, 2015 | 125 | 2015 |
Canine malignant hemangiosarcoma as a model of primitive angiogenic endothelium SP Fosmire, EB Dickerson, AM Scott, SR Bianco, MJ Pettengill, ... Laboratory Investigation 84 (5), 562-572, 2004 | 122 | 2004 |