| Fast native-SAD phasing for routine macromolecular structure determination T Weinert, V Olieric, S Waltersperger, E Panepucci, L Chen, H Zhang, ... Nature methods 12 (2), 131-133, 2015 | 145 | 2015 |
| A selective WDR5 degrader inhibits acute myeloid leukemia in patient-derived mouse models X Yu, D Li, J Kottur, Y Shen, HS Kim, KS Park, YH Tsai, W Gong, J Wang, ... Science translational medicine 13 (613), eabj1578, 2021 | 81 | 2021 |
| Pyrophosphate hydrolysis is an intrinsic and critical step of the DNA synthesis reaction J Kottur, DT Nair Nucleic Acids Research 46 (12), 5875-5885, 2018 | 67 | 2018 |
| A strategically located serine residue is critical for the mutator activity of DNA polymerase IV from Escherichia coli A Sharma, J Kottur, N Narayanan, DT Nair Nucleic acids research 41 (9), 5104-5114, 2013 | 46 | 2013 |
| Reactive oxygen species play an important role in the bactericidal activity of quinolone antibiotics J Kottur, DT Nair Angewandte Chemie International Edition 55 (7), 2397-2400, 2016 | 45 | 2016 |
| Discovery of a dual WDR5 and Ikaros PROTAC degrader as an anti-cancer therapeutic D Li, X Yu, J Kottur, W Gong, Z Zhang, AJ Storey, YH Tsai, H Uryu, Y Shen, ... Oncogene 41 (24), 3328-3340, 2022 | 31 | 2022 |
| Unique structural features in DNA polymerase IV enable efficient bypass of the N2 adduct induced by the nitrofurazone antibiotic J Kottur, A Sharma, KR Gore, N Narayanan, B Samanta, PI Pradeepkumar, ... Structure 23 (1), 56-67, 2015 | 28 | 2015 |
| Expression and purification of organic solvent stable lipase from soil metagenomic library M Khan, K Jithesh World Journal of Microbiology and Biotechnology 28, 2417-2424, 2012 | 25 | 2012 |
| High-resolution structures of the SARS-CoV-2 N7-methyltransferase inform therapeutic development J Kottur, O Rechkoblit, R Quintana-Feliciano, D Sciaky, AK Aggarwal Nature structural & molecular biology 29 (9), 850-853, 2022 | 18 | 2022 |
| The N2-Furfuryl-deoxyguanosine Adduct Does Not Alter the Structure of B-DNA PP Ghodke, KR Gore, S Harikrishna, B Samanta, J Kottur, DT Nair, ... The Journal of Organic Chemistry 81 (2), 502-511, 2016 | 17 | 2016 |
| A polar filter in DNA polymerases prevents ribonucleotide incorporation MK Johnson, J Kottur, DT Nair Nucleic acids research 47 (20), 10693-10705, 2019 | 16 | 2019 |
| A rescue act: Translesion DNA synthesis past N2‐deoxyguanosine adducts DT Nair, J Kottur, R Sharma IUBMB life 67 (7), 564-574, 2015 | 11 | 2015 |
| Cloning and characterization of two functionally diverse lipases from soil metagenome M Khan, K Jithesh, R Mookambikay The Journal of General and Applied Microbiology 59 (1), 21-31, 2013 | 10 | 2013 |
| Structures of SARS-CoV-2 N7-methyltransferase with DOT1L and PRMT7 inhibitors provide a platform for new antivirals J Kottur, KM White, ML Rodriguez, O Rechkoblit, R Quintana-Feliciano, ... PLoS Pathogens 19 (7), e1011546, 2023 | 6 | 2023 |
| A selective WDR5 degrader inhibits acute myeloid leukemia in patient-derived mouse models. Sci Transl Med, 13 (613), eabj1578 X Yu, D Li, J Kottur, Y Shen, HS Kim, KS Park, YH Tsai, W Gong, J Wang, ... | 5 | 2021 |
| H19 influenza A virus exhibits species-specific MHC class II receptor usage U Karakus, I Mena, J Kottur, SS El Zahed, R Seoane, S Yildiz, L Chen, ... Cell Host & Microbe, 2024 | 3 | 2024 |
| Nucleic acid mediated activation of a short prokaryotic argonaute immune system J Kottur, R Malik, AK Aggarwal Nature Communications 15 (1), 4852, 2024 | 3 | 2024 |
| Discovery of potent and selective WDR5 proteolysis targeting chimeras as potential therapeutics for pancreatic cancer X Yu, D Li, J Kottur, HS Kim, LE Herring, Y Yu, L Xie, X Hu, X Chen, L Cai, ... Journal of Medicinal Chemistry 66 (23), 16168-16186, 2023 | 3 | 2023 |
| Activation of CBASS Cap5 endonuclease immune effector by cyclic nucleotides O Rechkoblit, D Sciaky, DF Kreitler, A Buku, J Kottur, AK Aggarwal Nature Structural & Molecular Biology, 1-10, 2024 | 2 | 2024 |
| Burkholderia cenocepacia epigenetic regulator M. BceJIV simultaneously engages two DNA recognition sequences for methylation R Quintana-Feliciano, J Kottur, M Ni, R Ghosh, L Salas-Estrada, ... bioRxiv, 2024 | | 2024 |
