The anthelmintic drug praziquantel activates a schistosome transient receptor potential channel SK Park, GS Gunaratne, EG Chulkov, F Moehring, P McCusker, PI Dosa, ... Journal of Biological Chemistry 294 (49), 18873-18880, 2019 | 91 | 2019 |
Mechanism of praziquantel action at a parasitic flatworm ion channel SK Park, L Friedrich, NA Yahya, CM Rohr, EG Chulkov, D Maillard, ... Science translational medicine 13 (625), eabj5832, 2021 | 67 | 2021 |
The interaction of dipole modifiers with polyene-sterol complexes OS Ostroumova, SS Efimova, EG Chulkov, LV Schagina Public Library of Science 7 (9), e45135, 2012 | 36 | 2012 |
Effect of flavonoids on the phase separation in giant unilamellar vesicles formed from binary lipid mixtures OS Ostroumova, EG Chulkov, OV Stepanenko, LV Schagina Chemistry and Physics of Lipids 178, 77-83, 2014 | 27 | 2014 |
Membrane dipole modifiers modulate single-length nystatin channels via reducing elastic stress in the vicinity of the lipid mouth of a pore EG Chulkov, LV Schagina, OS Ostroumova Biochimica et Biophysica Acta (BBA)-Biomembranes 1848 (1), 192-199, 2015 | 22 | 2015 |
Phloretin modulates the rate of channel formation by polyenes EG Chulkov, OS Ostroumova Biochimica et Biophysica Acta (BBA)-Biomembranes 1858 (2), 289-294, 2016 | 16 | 2016 |
Identification of novel modulators of a schistosome transient receptor potential channel targeted by praziquantel EG Chulkov, E Smith, CM Rohr, NA Yahya, SK Park, L Scampavia, ... PLoS Neglected Tropical Diseases 15 (11), e0009898, 2021 | 14 | 2021 |
Direct visualization of solid ordered domains induced by polyene antibiotics in giant unilamellar vesicles EG Chulkov, SS Efimova, LV Schagina, OS Ostroumova Chemistry and Physics of Lipids 183, 204-207, 2014 | 14 | 2014 |
Loss of chloride channel 6 (CLC-6) affects vascular smooth muscle contractility and arterial stiffness via alterations to Golgi calcium stores CA Klemens, EG Chulkov, J Wu, MA Hye Khan, V Levchenko, MJ Flister, ... Hypertension 77 (2), 582-593, 2021 | 13 | 2021 |
Regulation of the pore-forming activity of Cecropin A by local anesthetics SS Efimova, RY Medvedev, EG Chulkov, LV Schagina, OS Ostroumova Cell and Tissue Biology 12, 331-341, 2018 | 10 | 2018 |
Lipid-mediated mode of action of local anesthetics on lipid pores induced by polyenes, peptides and lipopeptides SS Efimova, EG Chulkov, OS Ostroumova Colloids and Surfaces B: Biointerfaces 166, 1-8, 2018 | 9 | 2018 |
Electrophysiological characterization of a schistosome transient receptor potential channel activated by praziquantel EG Chulkov, O Palygin, NA Yahya, SK Park, JS Marchant International Journal for Parasitology 53 (8), 415-425, 2023 | 5 | 2023 |
Target-based discovery of a broad-spectrum flukicide DJ Sprague, SK Park, S Gramberg, L Bauer, CM Rohr, EG Chulkov, ... Nature Structural & Molecular Biology, 1-8, 2024 | 3 | 2024 |
The anthelmintic meclonazepam activates a schistosome transient receptor potential channel SK Park, DJ Sprague, CM Rohr, EG Chulkov, I Petrow, S Kumar, ... Journal of Biological Chemistry 300 (1), 2024 | 3 | 2024 |
Praziquantel activates a native cation current in Schistosoma mansoni EG Chulkov, CM Rohr, JS Marchant Frontiers in Parasitology 2, 1285177, 2023 | 3 | 2023 |
Use the force, fluke: Ligand-independent gating of Schistosoma mansoni ion channel TRPMPZQ EG Chulkov, E Isaeva, CL Stucky, JS Marchant International Journal for Parasitology 53 (8), 427-434, 2023 | 2 | 2023 |
IDENTIFICATION OF NOVEL MODULATORS OF A SCHISTOSOME TRANSIENT RECEPTOR POTENTIAL ION CHANNEL ACTIVATED BY PRAZIQUANTEL EG Chulkov, JS Marchant AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE 105 (5), 128-128, 2021 | | 2021 |
Lipid nanocomplexes of polyene macrolide antibiotics and plant polyphenols SS Efimova, EG Chulkov, OS Ostroumova Genes & Cells 14 (3), 80-80, 2019 | | 2019 |
Matrix lipid polyene nanocomplexes interact with model membranes EG Chulkov, SS Efimova, OS Ostroumova FEBS OPEN BIO 9, 381-381, 2019 | | 2019 |
Lipopeptide produced by Bacillus subtilis, fengycin, induces cation-permeable pores in model lipid membranes mimicking the target fungi membranes O Ostroumova, A Zakharova, S Efimova, E Chulkov, V Malev FEBS OPEN BIO 9, 14-14, 2019 | | 2019 |