Update of the standard numbering scheme for class B β-lactamases G Garau, I García-Sáez, C Bebrone, C Anne, P Mercuri, M Galleni, ... Antimicrobial agents and chemotherapy 48 (7), 2347-2349, 2004 | 393 | 2004 |
Structure and dynamics of a 197 bp nucleosome in complex with linker histone H1 J Bednar, I Garcia-Saez, R Boopathi, AR Cutter, G Papai, A Reymer, ... Molecular cell 66 (3), 384-397. e8, 2017 | 313 | 2017 |
Microtubule regulation in mitosis: tubulin phosphorylation by the cyclin-dependent kinase Cdk1 A Fourest-Lieuvin, L Peris, V Gache, I Garcia-Saez, C Juillan-Binard, ... Molecular biology of the cell 17 (3), 1041-1050, 2006 | 257 | 2006 |
The 1.5-Å structure of Chryseobacterium meningosepticum zinc β-lactamase in complex with the inhibitor, D-captopril I García-Sáez, J Hopkins, C Papamicael, N Franceschini, G Amicosante, ... Journal of biological chemistry 278 (26), 23868-23873, 2003 | 162 | 2003 |
Three‐dimensional crystal structure of the A‐tract DNA dodecamer d (CGCAAATTTGCG) complexed with the minor‐groove‐binding drug Hoechst 33258 MC Vega, I García Sáez, J Aymamí, R Eritja, GA Van Der Marel, ... European journal of biochemistry 222 (3), 721-726, 1994 | 159 | 1994 |
Three-dimensional structure of FEZ-1, a monomeric subclass B3 metallo-β-lactamase from Fluoribacter gormanii, in native form and in complex with D-captopril I Garcıa-Sáez, PS Mercuri, C Papamicaël, R Kahn, JM Frère, M Galleni, ... Journal of molecular biology 325 (4), 651-660, 2003 | 156 | 2003 |
The three-dimensional structure of VIM-2, a Zn-β-lactamase from Pseudomonas aeruginosa in its reduced and oxidised form I Garcia-Saez, JD Docquier, GM Rossolini, O Dideberg Journal of molecular biology 375 (3), 604-611, 2008 | 147 | 2008 |
Molecular Structure at 1· 8 Å of Mouse Liver Class Pi Glutathione S-transferase Complexed with S-(p-Nitrobenzyl) glutathione and Other Inhibitors I Garcı́a-Sáez, A Párraga, MF Phillips, TJ Mantle, M Coll Journal of molecular biology 237 (3), 298-314, 1994 | 127 | 1994 |
Structure of an H1-bound 6-nucleosome array reveals an untwisted two-start chromatin fiber conformation I Garcia-Saez, H Menoni, R Boopathi, MS Shukla, L Soueidan, ... Molecular cell 72 (5), 902-915. e7, 2018 | 112 | 2018 |
The three‐dimensional structure of human procarboxypeptidase A2. Deciphering the basis of the inhibition, activation and intrinsic activity of the zymogen I García‐Sáez, D Reverter, J Vendrell, FX Avilés, M Coll The EMBO journal, 1997 | 111 | 1997 |
Structure of human Eg5 in complex with a new monastrol-based inhibitor bound in the R configuration I Garcia-Saez, S DeBonis, R Lopez, F Trucco, B Rousseau, P Thuery, ... Journal of Biological Chemistry 282 (13), 9740-9747, 2007 | 99 | 2007 |
Eg5 targeting agents: From new anti-mitotic based inhibitor discovery to cancer therapy and resistance I Garcia-Saez, DA Skoufias Biochemical Pharmacology 184, 114364, 2021 | 87 | 2021 |
Crystal structure of the motor domain of the human kinetochore protein CENP-E I Garcia-Saez, T Yen, RH Wade, F Kozielski Journal of molecular biology 340 (5), 1107-1116, 2004 | 73 | 2004 |
Structural characterization of HBXIP: the protein that interacts with the anti-apoptotic protein survivin and the oncogenic viral protein HBx I Garcia-Saez, FB Lacroix, D Blot, F Gabel, DA Skoufias Journal of molecular biology 405 (2), 331, 2011 | 43 | 2011 |
H1–nucleosome interactions and their functional implications J Bednar, A Hamiche, S Dimitrov Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1859 (3), 436-443, 2016 | 41 | 2016 |
Probing the specificity of the subclass B3 FEZ-1 metallo-β-lactamase by site-directed mutagenesis PS Mercuri, I García-Sáez, K De Vriendt, I Thamm, B Devreese, ... Journal of Biological Chemistry 279 (32), 33630-33638, 2004 | 36 | 2004 |
The three-dimensional structure of a class-Pi glutathione S-transferase complexed with glutathione: the active-site hydration provides insights into the reaction mechanism A Párraga, I GARCÍA-SÁEZ, SB Walsh, TJ Mantle, M Coll Biochemical Journal 333 (3), 811-816, 1998 | 27 | 1998 |
Human kinetochore-associated kinesin CENP-E visualized at 17 Å resolution bound to microtubules E Neumann, I Garcia-Saez, S DeBonis, RH Wade, F Kozielski, JF Conway Journal of molecular biology 362 (2), 203-211, 2006 | 21 | 2006 |
The structure of human neuronal Rab6B in the active and inactive form I Garcia-Saez, S Tcherniuk, F Kozielski Acta Crystallographica Section D: Biological Crystallography 62 (7), 725-733, 2006 | 21 | 2006 |
Characterisation and preliminary X‐ray diffraction analysis of human pancreatic procarboxypeptidase A2 D Reverter, I Garcı́a-Sáez, L Catasús, J Vendrell, M Coll, FX Avilés FEBS letters 420 (1), 7-10, 1997 | 19 | 1997 |