CLP1 links tRNA metabolism to progressive motor-neuron loss T Hanada, S Weitzer, B Mair, C Bernreuther, BJ Wainger, J Ichida, ... Nature 495 (7442), 474-480, 2013 | 265 | 2013 |
Global genetic networks and the genotype-to-phenotype relationship M Costanzo, E Kuzmin, J van Leeuwen, B Mair, J Moffat, C Boone, ... Cell 177 (1), 85-100, 2019 | 206 | 2019 |
Digital microfluidic isolation of single cells for-Omics J Lamanna, EY Scott, HS Edwards, MD Chamberlain, MDM Dryden, ... Nature communications 11 (1), 5632, 2020 | 105 | 2020 |
Essential gene profiles for human pluripotent stem cells identify uncharacterized genes and substrate dependencies B Mair, J Tomic, SN Masud, P Tonge, A Weiss, M Usaj, AHY Tong, ... Cell reports 27 (2), 599-615. e12, 2019 | 104 | 2019 |
A selective and orally bioavailable VHL-recruiting PROTAC achieves SMARCA2 degradation in vivo C Kofink, N Trainor, B Mair, S Wöhrle, M Wurm, N Mischerikow, MJ Roy, ... Nature Communications 13 (1), 5969, 2022 | 94 | 2022 |
High-throughput genome-wide phenotypic screening via immunomagnetic cell sorting B Mair, PM Aldridge, RS Atwal, D Philpott, M Zhang, SN Masud, M Labib, ... Nature Biomedical Engineering 3 (10), 796-805, 2019 | 75 | 2019 |
Exploiting epigenetic vulnerabilities for cancer therapeutics B Mair, S Kubicek, SMB Nijman Trends in pharmacological sciences 35 (3), 136-145, 2014 | 75 | 2014 |
Gain- and Loss-of-Function Mutations in the Breast Cancer Gene GATA3 Result in Differential Drug Sensitivity B Mair, T Konopka, C Kerzendorfer, K Sleiman, S Salic, V Serra, ... PLoS genetics 12 (9), e1006279, 2016 | 58 | 2016 |
A cohesin traffic pattern genetically linked to gene regulation AL Valton, SV Venev, B Mair, ES Khokhar, AHY Tong, M Usaj, K Chan, ... Nature structural & molecular biology 29 (12), 1239-1251, 2022 | 37 | 2022 |
MEK inhibitors block growth of lung tumours with mutations in ataxia–telangiectasia mutated M Smida, F Fece de La Cruz, C Kerzendorfer, IZ Uras, B Mair, A Mazouzi, ... Nature communications 7 (1), 13701, 2016 | 37 | 2016 |
Genetic interaction networks in cancer cells B Mair, J Moffat, C Boone, BJ Andrews Current opinion in genetics & development 54, 64-72, 2019 | 36 | 2019 |
CRISPR screens are feasible in TP53 wild‐type cells KR Brown, B Mair, M Soste, J Moffat Molecular systems biology 15 (8), e8679, 2019 | 35 | 2019 |
Discovery of a highly selective cell‐active inhibitor of the histone lysine demethylases KDM2/7 PA Gerken, JR Wolstenhulme, A Tumber, SB Hatch, Y Zhang, S Müller, ... Angewandte Chemie International Edition 56 (49), 15555-15559, 2017 | 34 | 2017 |
Interrogation of cancer gene dependencies reveals paralog interactions of autosome and sex chromosome-encoded genes A Köferle, A Schlattl, A Hörmann, V Thatikonda, A Popa, F Spreitzer, ... Cell reports 39 (2), 2022 | 33 | 2022 |
Targeting a cell state common to triple‐negative breast cancers MK Muellner, B Mair, Y Ibrahim, C Kerzendorfer, H Lechtermann, ... Molecular Systems Biology 11 (2), 789, 2015 | 24 | 2015 |
Intron excision from precursor tRNA molecules in mammalian cells requires ATP hydrolysis and phosphorylation of tRNA-splicing endonuclease components B Mair, J Popow, K Mechtler, S Weitzer, J Martinez Biochemical Society Transactions 41 (4), 831-837, 2013 | 6 | 2013 |
High-throughput microfluidic cell sorting platform (MICS) D Philpott, P Aldridge, B Mair, R Atwal, S Masud, M Zhang, AHY Tong, ... | 4 | 2019 |
Genetic dependencies associated with transcription factor activities in human cancer cell lines V Thatikonda, V Supper, J Wachter, O Kaya, A Kombara, C Bilgilier, ... Cell Reports 43 (5), 2024 | 1 | 2024 |
Interrogation of cancer gene dependencies reveals novel paralog interactions of autosome and sex chromosome encoded genes A Köferle, A Schlattl, A Hörmann, F Spreitzer, A Popa, V Thatikonda, ... bioRxiv, 2021.05. 21.445116, 2021 | 1 | 2021 |
Scalable, FACS-Free Genome-Wide Phenotypic Screening B Mair, PM Aldridge, RS Atwal, SN Masud, M Zhang, D Philpott, ... bioRxiv, 612887, 2019 | 1 | 2019 |