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Mien-Chie Hung
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PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients
Y Nagata, KH Lan, X Zhou, M Tan, FJ Esteva, AA Sahin, KS Klos, P Li, ...
Cancer cell 6 (2), 117-127, 2004
22552004
Dual regulation of Snail by GSK-3β-mediated phosphorylation in control of epithelial–mesenchymal transition
BP Zhou, J Deng, W Xia, J Xu, YM Li, M Gunduz, MC Hung
Nature cell biology 6 (10), 931-940, 2004
18792004
Requirement for neuregulin receptor erbB2 in neural and cardiac development
KF Lee, H Simon, H Chen, B Bates, MC Hung, C Hauser
Nature 378 (6555), 394-398, 1995
16071995
The neu oncogene encodes an epidermal growth factor receptor-related protein
CI Bargmann, MC Hung, RA Weinberg
Nature 319 (6050), 226-230, 1986
15961986
Cytoplasmic localization of p21Cip1/WAF1 by Akt-induced phosphorylation in HER-2/neu-overexpressing cells
BP Zhou, Y Liao, W Xia, B Spohn, MH Lee, MC Hung
Nature cell biology 3 (3), 245-252, 2001
14002001
Multiple independent activations of the neu oncogene by a point mutation altering the transmembrane domain of p185
CI Bargmann, MC Hung, RA Weinberg
Cell 45 (5), 649-657, 1986
13621986
Nuclear localization of EGF receptor and its potential new role as a transcription factor
SY Lin, K Makino, W Xia, A Matin, Y Wen, KY Kwong, L Bourguignon, ...
Nature cell biology 3 (9), 802-808, 2001
13312001
An integrative genomic and proteomic analysis of PIK3CA, PTEN, and AKT mutations in breast cancer
K Stemke-Hale, AM Gonzalez-Angulo, A Lluch, RM Neve, WL Kuo, ...
Cancer research 68 (15), 6084-6091, 2008
11952008
Mechanisms of disease: understanding resistance to HER2-targeted therapy in human breast cancer
R Nahta, D Yu, MC Hung, GN Hortobagyi, FJ Esteva
Nature clinical practice Oncology 3 (5), 269-280, 2006
11942006
HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation
BP Zhou, Y Liao, W Xia, Y Zou, B Spohn, MC Hung
Nature cell biology 3 (11), 973-982, 2001
11852001
Neutralizing antibodies against epidermal growth factor and ErbB-2/neu receptor tyrosine kinases down-regulate vascular endothelial growth factor production by tumor cells in …
AM Petit, J Rak, MC Hung, P Rockwell, N Goldstein, B Fendly, RS Kerbel
The American journal of pathology 151 (6), 1523, 1997
11401997
Metformin and pathologic complete responses to neoadjuvant chemotherapy in diabetic patients with breast cancer
S Jiralerspong, SL Palla, SH Giordano, F Meric-Bernstam, C Liedtke, ...
Journal of clinical oncology 27 (20), 3297-3302, 2009
11042009
IκB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a
MCT Hu, DF Lee, W Xia, LS Golfman, F Ou-Yang, JY Yang, Y Zou, S Bao, ...
Cell 117 (2), 225-237, 2004
10892004
β-catenin, a novel prognostic marker for breast cancer: its roles in cyclin D1 expression and cancer progression
SY Lin, W Xia, JC Wang, KY Kwong, B Spohn, Y Wen, RG Pestell, ...
Proceedings of the National Academy of Sciences 97 (8), 4262-4266, 2000
10442000
The expression patterns of ER, PR, HER2, CK5/6, EGFR, Ki-67 and AR by immunohistochemical analysis in breast cancer cell lines
K Subik, JF Lee, L Baxter, T Strzepek, D Costello, P Crowley, L Xing, ...
Breast cancer: basic and clinical research 4, 117822341000400004, 2010
10392010
Glycosylation and stabilization of programmed death ligand-1 suppresses T-cell activity
CW Li, SO Lim, W Xia, HH Lee, LC Chan, CW Kuo, KH Khoo, SS Chang, ...
Nature communications 7 (1), 12632, 2016
9272016
p53 regulates epithelial–mesenchymal transition and stem cell properties through modulating miRNAs
CJ Chang, CH Chao, W Xia, JY Yang, Y Xiong, CW Li, WH Yu, ...
Nature cell biology 13 (3), 317-323, 2011
8842011
PARP inhibitor upregulates PD-L1 expression and enhances cancer-associated immunosuppression
S Jiao, W Xia, H Yamaguchi, Y Wei, MK Chen, JM Hsu, JL Hsu, WH Yu, ...
Clinical Cancer Research 23 (14), 3711-3720, 2017
8732017
Loss of FBP1 by Snail-mediated repression provides metabolic advantages in basal-like breast cancer
C Dong, T Yuan, Y Wu, Y Wang, TWM Fan, S Miriyala, Y Lin, J Yao, J Shi, ...
Cancer cell 23 (3), 316-331, 2013
8172013
IKKβ suppression of TSC1 links inflammation and tumor angiogenesis via the mTOR pathway
DF Lee, HP Kuo, CT Chen, JM Hsu, CK Chou, Y Wei, HL Sun, LY Li, ...
Cell 130 (3), 440-455, 2007
8162007
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