A bipartite signal mediates the transfer of type IV secretion substrates of Bartonella henselae into human cells R Schulein, P Guye, TA Rhomberg, MC Schmid, G Schröder, AC Vergunst, ... Proceedings of the National Academy of Sciences 102 (3), 856-861, 2005 | 297 | 2005 |
Rapid neurogenesis through transcriptional activation in human stem cells V Busskamp, NE Lewis, P Guye, AHM Ng, SL Shipman, SM Byrne, ... Molecular systems biology 10 (11), 760, 2014 | 253 | 2014 |
Host cell interactome of tyrosine-phosphorylated bacterial proteins M Selbach, FE Paul, S Brandt, P Guye, O Daumke, S Backert, C Dehio, ... Cell host & microbe 5 (4), 397-403, 2009 | 206 | 2009 |
Genetically engineering self-organization of human pluripotent stem cells into a liver bud-like tissue using Gata6 P Guye, MR Ebrahimkhani, N Kipniss, JJ Velazquez, E Schoenfeld, ... Nature communications 7 (1), 10243, 2016 | 171 | 2016 |
A platform for rapid prototyping of synthetic gene networks in mammalian cells X Duportet, L Wroblewska, P Guye, Y Li, J Eyquem, J Rieders, T Rimchala, ... Nucleic acids research 42 (21), 13440-13451, 2014 | 165 | 2014 |
A translocated bacterial protein protects vascular endothelial cells from apoptosis MC Schmid, F Scheidegger, M Dehio, N Balmelle-Devaux, R Schulein, ... PLoS pathogens 2 (11), e115, 2006 | 154 | 2006 |
Rapid, modular and reliable construction of complex mammalian gene circuits P Guye, Y Li, L Wroblewska, X Duportet, R Weiss Nucleic acids research 41 (16), e156-e156, 2013 | 109 | 2013 |
Synthetic morphogenesis BP Teague, P Guye, R Weiss Cold Spring Harbor perspectives in biology 8 (9), a023929, 2016 | 101 | 2016 |
A translocated protein of Bartonella henselae interferes with endocytic uptake of individual bacteria and triggers uptake of large bacterial aggregates via the … TA Rhomberg, MC Truttmann, P Guye, Y Ellner, C Dehio Cellular microbiology 11 (6), 927-945, 2009 | 76 | 2009 |
Comparing in vitro human liver models to in vivo human liver using RNA-Seq R Gupta, Y Schrooders, D Hauser, M van Herwijnen, W Albrecht, ... Archives of toxicology 95, 573-589, 2021 | 73 | 2021 |
Fic domain‐catalyzed adenylylation: insight provided by the structural analysis of the type IV secretion system effector BepA DV Palanivelu, A Goepfert, M Meury, P Guye, C Dehio, T Schirmer Protein science 20 (3), 492-499, 2011 | 63 | 2011 |
Distinct activities of Bartonella henselae type IV secretion effector proteins modulate capillary‐like sprout formation F Scheidegger, Y Ellner, P Guye, TA Rhomberg, H Weber, HG Augustin, ... Cellular microbiology 11 (7), 1088-1101, 2009 | 55 | 2009 |
Preserved DNA damage checkpoint pathway protects against complications in long-standing type 1 diabetes S Bhatt, MK Gupta, M Khamaisi, R Martinez, MA Gritsenko, BK Wagner, ... Cell metabolism 22 (2), 239-252, 2015 | 48 | 2015 |
A Translocated Effector Required for Bartonella Dissemination from Derma to Blood Safeguards Migratory Host Cells from Damage by Co-translocated Effectors R Okujava, P Guye, YY Lu, C Mistl, F Polus, M Vayssier-Taussat, C Halin, ... PLoS pathogens 10 (6), e1004187, 2014 | 46 | 2014 |
Microbead-based biomimetic synthetic neighbors enhance survival and function of rat pancreatic β-cells W Li, S Lee, M Ma, SM Kim, P Guye, JR Pancoast, DG Anderson, R Weiss, ... Scientific reports 3 (1), 2863, 2013 | 46 | 2013 |
Network integration and modelling of dynamic drug responses at multi-omics levels N Selevsek, F Caiment, R Nudischer, H Gmuender, I Agarkova, ... Communications biology 3 (1), 573, 2020 | 35 | 2020 |
Design and connection of robust genetic circuits A Randall, P Guye, S Gupta, X Duportet, R Weiss Methods in enzymology 497, 159-186, 2011 | 34 | 2011 |
BID-F1 and BID-F2 domains of Bartonella henselae effector protein BepF trigger together with BepC the formation of invasome structures MC Truttmann, P Guye, C Dehio PLoS One 6 (10), e25106, 2011 | 25 | 2011 |
A 3D heterotypic multicellular tumor spheroid assay platform to discriminate drug effects on stroma versus cancer cells Z Weydert, M Lal-Nag, L Mathews-Greiner, C Thiel, H Cordes, L Küpfer, ... SLAS DISCOVERY: Advancing the Science of Drug Discovery 25 (3), 265-276, 2020 | 24 | 2020 |
Engineering a heterogeneous tissue from pluripotent stem cells P Guye, R Weiss, MR Ebrahimkhani US Patent 9,677,085, 2017 | 14 | 2017 |