Small molecules enhance CRISPR genome editing in pluripotent stem cells C Yu, Y Liu, T Ma, K Liu, S Xu, Y Zhang, H Liu, M La Russa, M Xie, S Ding, ... Cell stem cell 16 (2), 142-147, 2015 | 492 | 2015 |
Conversion of human fibroblasts into functional cardiomyocytes by small molecules N Cao, Y Huang, J Zheng, CI Spencer, Y Zhang, JD Fu, B Nie, M Xie, ... Science 352 (6290), 1216-1220, 2016 | 398 | 2016 |
Organocatalytic asymmetric transformations of modified Morita–Baylis–Hillman adducts TY Liu, M Xie, YC Chen Chemical Society Reviews 41 (11), 4101-4112, 2012 | 397 | 2012 |
Metabolic control of TH17 and induced Treg cell balance by an epigenetic mechanism T Xu, KM Stewart, X Wang, K Liu, M Xie, JK Ryu, K Li, T Ma, H Wang, L Ni, ... Nature 548 (7666), 228-233, 2017 | 312 | 2017 |
Scalable production of iPSC-derived human neurons to identify tau-lowering compounds by high-content screening C Wang, ME Ward, R Chen, K Liu, TE Tracy, X Chen, M Xie, PD Sohn, ... Stem cell reports 9 (4), 1221-1233, 2017 | 294 | 2017 |
Halofuginone attenuates osteoarthritis by inhibition of TGF-β activity and H-type vessel formation in subchondral bone Z Cui, J Crane, H Xie, X Jin, G Zhen, C Li, L Xie, L Wang, Q Bian, T Qiu, ... Annals of the rheumatic diseases 75 (9), 1714-1721, 2016 | 230 | 2016 |
A novel YAP1 inhibitor targets CSC-enriched radiation-resistant cells and exerts strong antitumor activity in esophageal adenocarcinoma S Song, M Xie, AW Scott, J Jin, L Ma, X Dong, HD Skinner, RL Johnson, ... Molecular cancer therapeutics 17 (2), 443-454, 2018 | 169 | 2018 |
Progress in the reprogramming of somatic cells T Ma, M Xie, T Laurent, S Ding Circulation research 112 (3), 562-574, 2013 | 160 | 2013 |
Chem-seq permits identification of genomic targets of drugs against androgen receptor regulation selected by functional phenotypic screens C Jin, L Yang, M Xie, C Lin, D Merkurjev, JC Yang, B Tanasa, S Oh, ... Proceedings of the National Academy of Sciences 111 (25), 9235-9240, 2014 | 75 | 2014 |
YAP1-mediated CDK6 activation confers radiation resistance in esophageal cancer–Rationale for the combination of YAP1 and CDK4/6 inhibitors in esophageal cancer F Li, Y Xu, B Liu, PK Singh, W Zhao, J Jin, G Han, AW Scott, X Dong, ... Clinical Cancer Research 25 (7), 2264-2277, 2019 | 62 | 2019 |
Chemical modulation of cell fate in stem cell therapeutics and regenerative medicine K Liu, C Yu, M Xie, K Li, S Ding Cell chemical biology 23 (8), 893-916, 2016 | 57 | 2016 |
(R)‐3‐Methyl‐3‐Phenyl‐1‐Pentene Via Catalytic Asymmetric Hydrovinylation CR Smith, A Zhang, DJ Mans, TV RajanBabu, SE Denmark, M Xie Organic Syntheses, 248-266, 2008 | 46 | 2008 |
Lewis acid-promoted conjugate addition of dienol silyl ethers to nitroalkenes: Synthesis of 3-substituted azepanes M Xie, SE Denmark The Journal of organic chemistry 72 (18), 7050-7053, 2007 | 45 | 2007 |
Concise review: chemical approaches for modulating lineage-specific stem cells and progenitors T Xu, M Zhang, T Laurent, M Xie, S Ding Stem Cells Translational Medicine 2 (5), 355-361, 2013 | 40 | 2013 |
Patient-specific induced pluripotent stem cells for disease modeling and phenotypic drug discovery: miniperspective S Tang, M Xie, N Cao, S Ding Journal of medicinal chemistry 59 (1), 2-15, 2016 | 36 | 2016 |
Small molecules for cell reprogramming and heart repair: progress and perspective M Xie, N Cao, S Ding ACS chemical biology 9 (1), 34-44, 2014 | 32 | 2014 |
Galectin-3 expression is prognostic in diffuse type gastric adenocarcinoma, confers aggressive phenotype, and can be targeted by YAP1/BET inhibitors JA Ajani, JS Estrella, Q Chen, AM Correa, L Ma, AW Scott, J Jin, B Liu, ... British journal of cancer 118 (1), 52-61, 2018 | 26 | 2018 |
Pharmacological reprogramming of somatic cells for regenerative medicine M Xie, S Tang, K Li, S Ding Accounts of Chemical Research 50 (5), 1202-1211, 2017 | 20 | 2017 |
Discovery of small molecules that normalize the transcriptome and enhance cysteine cathepsin activity in progranulin-deficient microglia MA Telpoukhovskaia, K Liu, FA Sayed, JI Etchegaray, M Xie, L Zhan, Y Li, ... Scientific reports 10 (1), 13688, 2020 | 19 | 2020 |
Sensitizing ovarian cancer cells to chemotherapy by interfering with pathways that are involved in the formation of cancer stem cells K Saydaminova, R Strauss, M Xie, J Bartek, M Richter, R van Rensburg, ... Cancer biology & therapy 17 (10), 1079-1088, 2016 | 11 | 2016 |