Metabolic effects of influenza virus infection in cultured animal cells: Intra-and extracellular metabolite profiling JB Ritter, AS Wahl, S Freund, Y Genzel, U Reichl BMC systems biology 4, 1-22, 2010 | 236 | 2010 |
Enhancing the enantioselectivity of an epoxide hydrolase by directed evolution MT Reetz, C Torre, A Eipper, R Lohmer, M Hermes, B Brunner, ... Organic letters 6 (2), 177-180, 2004 | 202 | 2004 |
Continuous cell lines as a production system for influenza vaccines Y Genzel, U Reichl Expert review of vaccines 8 (12), 1681-1692, 2009 | 195 | 2009 |
Metabolism of MDCK cells during cell growth and influenza virus production in large-scale microcarrier culture Y Genzel, I Behrendt, S König, H Sann, U Reichl Vaccine 22 (17-18), 2202-2208, 2004 | 195 | 2004 |
Wave microcarrier cultivation of MDCK cells for influenza virus production in serum containing and serum-free media Y Genzel, RM Olmer, B Schäfer, U Reichl Vaccine 24 (35-36), 6074-6087, 2006 | 154 | 2006 |
Bioreactors for high cell density and continuous multi-stage cultivations: options for process intensification in cell culture-based viral vaccine production F Tapia, D Vázquez-Ramírez, Y Genzel, U Reichl Applied microbiology and biotechnology 100, 2121-2132, 2016 | 145 | 2016 |
Substitution of glutamine by pyruvate to reduce ammonia formation and growth inhibition of mammalian cells Y Genzel, JB Ritter, S König, R Alt, U Reichl Biotechnology progress 21 (1), 58-69, 2005 | 143 | 2005 |
Designing cell lines for viral vaccine production: Where do we stand? Y Genzel Biotechnology journal 10 (5), 728-740, 2015 | 132 | 2015 |
Serum-free influenza virus production avoiding washing steps and medium exchange in large-scale microcarrier culture Y Genzel, M Fischer, U Reichl Vaccine 24 (16), 3261-3272, 2006 | 125 | 2006 |
New avian suspension cell lines provide production of influenza virus and MVA in serum-free media: studies on growth, metabolism and virus propagation V Lohr, A Rath, Y Genzel, I Jordan, V Sandig, U Reichl Vaccine 27 (36), 4975-4982, 2009 | 124 | 2009 |
High cell density cultivations by alternating tangential flow (ATF) perfusion for influenza A virus production using suspension cells Y Genzel, T Vogel, J Buck, I Behrendt, DV Ramirez, G Schiedner, I Jordan, ... Vaccine 32 (24), 2770-2781, 2014 | 122 | 2014 |
MDCK and Vero cells for influenza virus vaccine production: a one-to-one comparison up to lab-scale bioreactor cultivation Y Genzel, C Dietzsch, E Rapp, J Schwarzer, U Reichl Applied microbiology and biotechnology 88, 461-475, 2010 | 121 | 2010 |
Simultaneous extraction of several metabolites of energy metabolism and related substances in mammalian cells: optimization using experimental design JB Ritter, Y Genzel, U Reichl Analytical biochemistry 373 (2), 349-369, 2008 | 121 | 2008 |
Quantitative analysis of cellular proteome alterations in human influenza A virus‐infected mammalian cell lines D Vester, E Rapp, D Gade, Y Genzel, U Reichl Proteomics 9 (12), 3316-3327, 2009 | 117 | 2009 |
Continuous influenza virus production in cell culture shows a periodic accumulation of defective interfering particles T Frensing, FS Heldt, A Pflugmacher, I Behrendt, I Jordan, D Flockerzi, ... PloS one 8 (9), e72288, 2013 | 115 | 2013 |
Bioreactor concepts for cell culture-based viral vaccine production LE Gallo–Ramírez, A Nikolay, Y Genzel, U Reichl Expert review of Vaccines 14 (9), 1181-1195, 2015 | 112 | 2015 |
Infection dynamics and virus-induced apoptosis in cell culture-based influenza vaccine production—Flow cytometry and mathematical modeling J Schulze-Horsel, M Schulze, G Agalaridis, Y Genzel, U Reichl Vaccine 27 (20), 2712-2722, 2009 | 111 | 2009 |
Harvesting and concentration of human influenza A virus produced in serum‐free mammalian cell culture for the production of vaccines B Kalbfuss, Y Genzel, M Wolff, A Zimmermann, R Morenweiser, U Reichl Biotechnology and bioengineering 97 (1), 73-85, 2007 | 110 | 2007 |
Glycan analysis in cell culture-based influenza vaccine production: influence of host cell line and virus strain on the glycosylation pattern of viral hemagglutinin J Schwarzer, E Rapp, R Hennig, Y Genzel, I Jordan, V Sandig, U Reichl Vaccine 27 (32), 4325-4336, 2009 | 109 | 2009 |
PPARα and fatty acid oxidation mediate glucocorticoid resistance in chronic lymphocytic leukemia S Tung, Y Shi, K Wong, F Zhu, R Gorczynski, RC Laister, M Minden, ... Blood, The Journal of the American Society of Hematology 122 (6), 969-980, 2013 | 108 | 2013 |