| Stromal cell diversity associated with immune evasion in human triple‐negative breast cancer SZ Wu, DL Roden, C Wang, H Holliday, K Harvey, AS Cazet, KJ Murphy, ... The EMBO journal 39 (19), e104063, 2020 | 291 | 2020 |
| CAF hierarchy driven by pancreatic cancer cell p53-status creates a pro-metastatic and chemoresistant environment via perlecan C Vennin, P Mélénec, R Rouet, M Nobis, AS Cazet, KJ Murphy, ... Nature communications 10 (1), 3637, 2019 | 220 | 2019 |
| Reshaping the tumor stroma for treatment of pancreatic cancer C Vennin, KJ Murphy, JP Morton, TR Cox, M Pajic, P Timpson Gastroenterology 154 (4), 820-838, 2018 | 204 | 2018 |
| Tailored first-line and second-line CDK4-targeting treatment combinations in mouse models of pancreatic cancer A Chou, D Froio, AM Nagrial, A Parkin, KJ Murphy, VT Chin, D Wohl, ... Gut 67 (12), 2142-2155, 2018 | 125 | 2018 |
| Temporal profiling of the breast tumour microenvironment reveals collagen XII as a driver of metastasis M Papanicolaou, AL Parker, M Yam, EC Filipe, SZ Wu, JL Chitty, K Wyllie, ... Nature communications 13 (1), 4587, 2022 | 95 | 2022 |
| Ral GTPases promote breast cancer metastasis by controlling biogenesis and organ targeting of exosomes S Ghoroghi, B Mary, A Larnicol, N Asokan, A Klein, N Osmani, I Busnelli, ... Elife 10, e61539, 2021 | 94 | 2021 |
| Intravital FRAP imaging using an E-cadherin-GFP mouse reveals disease-and drug-dependent dynamic regulation of cell-cell junctions in live tissue Z Erami, D Herrmann, SC Warren, M Nobis, EJ McGhee, MC Lucas, ... Cell reports 14 (1), 152-167, 2016 | 71 | 2016 |
| Intravital imaging to monitor therapeutic response in moving hypoxic regions resistant to PI3K pathway targeting in pancreatic cancer JRW Conway, SC Warren, D Herrmann, KJ Murphy, AS Cazet, C Vennin, ... Cell reports 23 (11), 3312-3326, 2018 | 68 | 2018 |
| ROCK-mediated selective activation of PERK signalling causes fibroblast reprogramming and tumour progression through a CRELD2-dependent mechanism ST Boyle, V Poltavets, J Kular, NT Pyne, JJ Sandow, AC Lewis, ... Nature Cell Biology 22 (7), 882-895, 2020 | 60 | 2020 |
| Single-cell transcriptomics reveals involution mimicry during the specification of the basal breast cancer subtype F Valdes-Mora, R Salomon, BS Gloss, AMK Law, J Venhuizen, L Castillo, ... Cell Reports 35 (2), 2021 | 56 | 2021 |
| Targeting promiscuous heterodimerization overcomes innate resistance to ERBB2 dimerization inhibitors in breast cancer SP Kennedy, JZR Han, N Portman, M Nobis, JF Hastings, KJ Murphy, ... Breast Cancer Research 21, 1-17, 2019 | 44 | 2019 |
| Molecular mobility and activity in an intravital imaging setting–implications for cancer progression and targeting M Nobis, SC Warren, MC Lucas, KJ Murphy, D Herrmann, P Timpson Journal of Cell Science 131 (5), jcs206995, 2018 | 35 | 2018 |
| Intravital imaging technology guides FAK-mediated priming in pancreatic cancer precision medicine according to Merlin status KJ Murphy, DA Reed, C Vennin, JRW Conway, M Nobis, JX Yin, ... Science advances 7 (40), eabh0363, 2021 | 32 | 2021 |
| Three-dimensional organotypic matrices from alternative collagen sources as pre-clinical models for cell biology JRW Conway, C Vennin, AS Cazet, D Herrmann, KJ Murphy, SC Warren, ... Scientific Reports 7 (1), 16887, 2017 | 31 | 2017 |
| MCL-1 antagonism enhances the anti-invasive effects of dasatinib in pancreatic adenocarcinoma L Castillo, AIJ Young, A Mawson, P Schafranek, AM Steinmann, ... Oncogene 39 (8), 1821-1829, 2020 | 24 | 2020 |
| A first-in-class pan-lysyl oxidase inhibitor impairs stromal remodeling and enhances gemcitabine response and survival in pancreatic cancer JL Chitty, M Yam, L Perryman, AL Parker, JN Skhinas, YFI Setargew, ... Nature Cancer 4 (9), 1326-1344, 2023 | 20 | 2023 |
| Co-trimoxazole for systemic leishmaniasis. KJ Murphy, ACW Bong | 20 | 1981 |
| Optimizing metastatic-cascade-dependent Rac1 targeting in breast cancer: Guidance using optical window intravital FRET imaging A Floerchinger, KJ Murphy, SL Latham, SC Warren, AT McCulloch, ... Cell Reports 36 (11), 2021 | 16 | 2021 |
| Annexin A6 and NPC1 regulate LDL-inducible cell migration and distribution of focal adhesions J Jose, M Hoque, J Engel, SS Beevi, M Wahba, MI Georgieva, KJ Murphy, ... Scientific Reports 12 (1), 596, 2022 | 13 | 2022 |
| Focal adhesion kinase priming in pancreatic cancer, altering biomechanics to improve chemotherapy KJ Murphy, J Zhu, M Trpceski, BA Pereira, P Timpson, D Herrmann Biochemical Society Transactions 50 (4), 1129-1141, 2022 | 12 | 2022 |
