| Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis R Kayed, E Head, JL Thompson, TM McIntire, SC Milton, CW Cotman, ... Science 300 (5618), 486-489, 2003 | 4973 | 2003 |
| Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Aβ and synaptic dysfunction S Oddo, A Caccamo, JD Shepherd, MP Murphy, TE Golde, R Kayed, ... Neuron 39 (3), 409-421, 2003 | 4894 | 2003 |
| A specific amyloid-β protein assembly in the brain impairs memory S Lesné, MT Koh, L Kotilinek, R Kayed, CG Glabe, A Yang, M Gallagher, ... Nature 440 (7082), 352-357, 2006 | 3485 | 2006 |
| Curcumin inhibits formation of amyloid β oligomers and fibrils, binds plaques, and reduces amyloid in vivo F Yang, GP Lim, AN Begum, OJ Ubeda, MR Simmons, SS Ambegaokar, ... Journal of Biological Chemistry 280 (7), 5892-5901, 2005 | 2885 | 2005 |
| Calcium Dysregulation and Membrane Disruption as a Ubiquitous Neurotoxic Mechanism of Soluble Amyloid Oligomers*♦ A Demuro, E Mina, R Kayed, SC Milton, I Parker, CG Glabe Journal of Biological Chemistry 280 (17), 17294-17300, 2005 | 1298 | 2005 |
| Permeabilization of lipid bilayers is a common conformation-dependent activity of soluble amyloid oligomers in protein misfolding diseases R Kayed, Y Sokolov, B Edmonds, TM McIntire, SC Milton, JE Hall, ... Journal of Biological Chemistry 279 (45), 46363-46366, 2004 | 1122 | 2004 |
| NLRP3 inflammasome activation drives tau pathology C Ising, C Venegas, S Zhang, H Scheiblich, SV Schmidt, A Vieira-Saecker, ... Nature 575 (7784), 669-673, 2019 | 976 | 2019 |
| iPSC-derived human microglia-like cells to study neurological diseases EM Abud, RN Ramirez, ES Martinez, LM Healy, CHH Nguyen, ... Neuron 94 (2), 278-293. e9, 2017 | 900 | 2017 |
| Fibril specific, conformation dependent antibodies recognize a generic epitope common to amyloid fibrils and fibrillar oligomers that is absent in prefibrillar oligomers R Kayed, E Head, F Sarsoza, T Saing, CW Cotman, M Necula, L Margol, ... Molecular neurodegeneration 2, 1-11, 2007 | 887 | 2007 |
| Small molecule inhibitors of aggregation indicate that amyloid β oligomerization and fibrillization pathways are independent and distinct M Necula, R Kayed, S Milton, CG Glabe Journal of Biological Chemistry 282 (14), 10311-10324, 2007 | 865 | 2007 |
| The role of amyloid-β oligomers in toxicity, propagation, and immunotherapy U Sengupta, AN Nilson, R Kayed EBioMedicine 6, 42-49, 2016 | 740 | 2016 |
| Tau oligomers impair memory and induce synaptic and mitochondrial dysfunction in wild-type mice CA Lasagna-Reeves, DL Castillo-Carranza, U Sengupta, AL Clos, ... Molecular neurodegeneration 6, 1-14, 2011 | 625 | 2011 |
| Small misfolded Tau species are internalized via bulk endocytosis and anterogradely and retrogradely transported in neurons JW Wu, M Herman, L Liu, S Simoes, CM Acker, H Figueroa, JI Steinberg, ... Journal of Biological Chemistry 288 (3), 1856-1870, 2013 | 581 | 2013 |
| Identification of oligomers at early stages of tau aggregation in Alzheimer's disease CA Lasagna-Reeves, DL Castillo-Carranza, U Sengupta, J Sarmiento, ... The FASEB Journal 26 (5), 1946, 2012 | 558 | 2012 |
| Alzheimer brain-derived tau oligomers propagate pathology from endogenous tau CA Lasagna-Reeves, DL Castillo-Carranza, U Sengupta, ... Scientific reports 2 (1), 700, 2012 | 550 | 2012 |
| Molecular mechanisms of amyloid oligomers toxicity R Kayed, CA Lasagna-Reeves Journal of Alzheimer's Disease 33 (s1), S67-S78, 2013 | 547 | 2013 |
| Common structure and toxic function of amyloid oligomers implies a common mechanism of pathogenesis CG Glabe, R Kayed Neurology 66 (1_suppl_1), S74-S78, 2006 | 493 | 2006 |
| Amyloid oligomers: A joint experimental/computational perspective on Alzheimer’s disease, Parkinson’s disease, type II diabetes, and amyotrophic lateral sclerosis PH Nguyen, A Ramamoorthy, BR Sahoo, J Zheng, P Faller, JE Straub, ... Chemical reviews 121 (4), 2545-2647, 2021 | 485 | 2021 |
| Structural and dynamic features of Alzheimer's Aβ peptide in amyloid fibrils studied by site-directed spin labeling M Torok, S Milton, R Kayed, P Wu, T McIntire, CG Glabe, R Langen Journal of Biological Chemistry 277 (43), 40810-40815, 2002 | 461 | 2002 |
| Conformational transitions of islet amyloid polypeptide (IAPP) in amyloid formation in vitro R Kayed, J Bernhagen, N Greenfield, K Sweimeh, H Brunner, W Voelter, ... Journal of molecular biology 287 (4), 781-796, 1999 | 444 | 1999 |
