Essential role of Plzf in maintenance of spermatogonial stem cells JA Costoya, RM Hobbs, M Barna, G Cattoretti, K Manova, M Sukhwani, ... Nature genetics 36 (6), 653-659, 2004 | 1101 | 2004 |
Plzf mediates transcriptional repression of HoxD gene expression through chromatin remodeling M Barna, T Merghoub, JA Costoya, D Ruggero, M Branford, A Bergia, ... Developmental cell 3 (4), 499-510, 2002 | 202 | 2002 |
Fluorescent drug-loaded, polymeric-based, branched gold nanoshells for localized multimodal therapy and imaging of tumoral cells A Topete, M Alatorre-Meda, P Iglesias, EM Villar-Alvarez, S Barbosa, ... ACS nano 8 (3), 2725-2738, 2014 | 192 | 2014 |
AMPK activation by oncogenesis is required to maintain cancer cell proliferation in astrocytic tumors M Ríos, M Foretz, B Viollet, A Prieto, M Fraga, JA Costoya, R Señarís Cancer research 73 (8), 2628-2638, 2013 | 147 | 2013 |
Activation of growth hormone receptor delivers an antiapoptotic signal: evidence for a role of Akt in this pathway JA Costoya, J Finidori, S Moutoussamy, R Señaris, J Devesa, VM Arce Endocrinology 140 (12), 5937-5943, 1999 | 140 | 1999 |
Functional analysis of the role of POK transcriptional repressors JA Costoya Briefings in Functional Genomics and Proteomics 6 (1), 8-18, 2007 | 128 | 2007 |
Activation of human somatostatin receptor 2 promotes apoptosis through a mechanism that is independent from induction of p53 R Teijeiro, R Ríos, J Costoya, R Castro, J Bello, J Devesa, V Arce Cellular Physiology and Biochemistry 12 (1), 31-38, 2002 | 122 | 2002 |
NK cell-based glioblastoma immunotherapy I Golán, L Rodriguez de la Fuente, JA Costoya Cancers 10 (12), 522, 2018 | 68 | 2018 |
The role of promyelocytic leukemia zinc finger and promyelocytic leukemia in leukemogenesis and development JA Costoya, PP Pandolfi Current opinion in hematology 8 (4), 212-217, 2001 | 63 | 2001 |
Disruption of PLZP in mice leads to increased T-lymphocyte proliferation, cytokine production, and altered hematopoietic stem cell homeostasis F Piazza, JA Costoya, T Merghoub, RM Hobbs, PP Pandolfi Molecular and cellular biology 24 (23), 10456-10469, 2004 | 61 | 2004 |
Expression of growth hormone receptor in the human brain JR Castro, JA Costoya, R Gallego, A Prieto, VM Arce, R Señarı́s Neuroscience letters 281 (2-3), 147-150, 2000 | 54 | 2000 |
Cyclin-dependent kinase antagonizes promyelocytic leukemia zinc-finger through phosphorylation JA Costoya, RM Hobbs, PP Pandolfi Oncogene 27 (27), 3789-3796, 2008 | 52 | 2008 |
SARS-CoV-2 infection in K18-ACE2 transgenic mice replicates human pulmonary disease in COVID-19 VM Arce, JA Costoya Cellular & Molecular Immunology 18 (3), 513-514, 2021 | 45 | 2021 |
Retinoblastoma loss modulates DNA damage response favoring tumor progression M Seoane, P Iglesias, T Gonzalez, F Dominguez, M Fraga, C Aliste, ... PLoS One 3 (11), e3632, 2008 | 41 | 2008 |
A novel BRET-based genetically encoded biosensor for functional imaging of hypoxia P Iglesias, JA Costoya Biosensors and Bioelectronics 24 (10), 3126-3130, 2009 | 40 | 2009 |
The mitochondrial genome is a “genetic sanctuary” during the oncogenic process M Seoane, A Mosquera-Miguel, T Gonzalez, M Fraga, A Salas, ... PloS one 6 (8), e23327, 2011 | 32 | 2011 |
Lipoprotein internalisation induced by oncogenic AMPK activation is essential to maintain glioblastoma cell growth M Rios, M Foretz, B Viollet, A Prieto, M Fraga, T García-Caballero, ... European Journal of Cancer 50 (18), 3187-3197, 2014 | 30 | 2014 |
NIR-light active hybrid nanoparticles for combined imaging and bimodal therapy of cancerous cells A Topete, D Melgar, M Alatorre-Meda, P Iglesias, B Argibay, S Vidawati, ... Journal of Materials Chemistry B 2 (40), 6967-6977, 2014 | 25 | 2014 |
Salivary gland is capable of GH synthesis under GHRH stimulation JAF Tresguerres, C Ariznavarreta, B Granados, JA Costoya, ... Journal of endocrinology 160 (2), 217-222, 1999 | 23 | 1999 |
RB mutation and RAS overexpression induce resistance to NK cell-mediated cytotoxicity in glioma cells M Orozco-Morales, FJ Sánchez-García, I Golán-Cancela, ... Cancer cell international 15, 1-11, 2015 | 22 | 2015 |