Implications of the presence of N-glycolylneuraminic acid in recombinant therapeutic glycoproteins D Ghaderi, RE Taylor, V Padler-Karavani, S Diaz, A Varki Nature biotechnology 28 (8), 863-867, 2010 | 431 | 2010 |
Diversity in specificity, abundance, and composition of anti-Neu5Gc antibodies in normal humans: potential implications for disease V Padler-Karavani, H Yu, H Cao, H Chokhawala, F Karp, N Varki, X Chen, ... Glycobiology 18 (10), 818-830, 2008 | 367 | 2008 |
Evidence for a human-specific mechanism for diet and antibody-mediated inflammation in carcinoma progression M Hedlund, V Padler-Karavani, NM Varki, A Varki Proceedings of the National Academy of Sciences 105 (48), 18936-18941, 2008 | 227 | 2008 |
Novel mechanism for the generation of human xeno-autoantibodies against the nonhuman sialic acid N-glycolylneuraminic acid RE Taylor, CJ Gregg, V Padler-Karavani, D Ghaderi, H Yu, S Huang, ... Journal of Experimental Medicine 207 (8), 1637-1646, 2010 | 173 | 2010 |
Sensitive and specific detection of the non-human sialic Acid N-glycolylneuraminic acid in human tissues and biotherapeutic products SL Diaz, V Padler-Karavani, D Ghaderi, N Hurtado-Ziola, H Yu, X Chen, ... PloS one 4 (1), e4241, 2009 | 168 | 2009 |
Potential impact of the non-human sialic acid N-glycolylneuraminic acid on transplant rejection risk V Padler-Karavani, A Varki Xenotransplantation 18 (1), 1, 2011 | 165 | 2011 |
Human xeno-autoantibodies against a non-human sialic acid serve as novel serum biomarkers and immunotherapeutics in cancer V Padler-Karavani, N Hurtado-Ziola, M Pu, H Yu, S Huang, S Muthana, ... Cancer research 71 (9), 3352-3363, 2011 | 152 | 2011 |
Cross-comparison of protein recognition of sialic acid diversity on two novel sialoglycan microarrays V Padler-Karavani, X Song, H Yu, N Hurtado-Ziola, S Huang, S Muthana, ... Journal of Biological Chemistry 287 (27), 22593-22608, 2012 | 144 | 2012 |
Long-term IgG response to porcine Neu5Gc antigens without transmission of PERV in burn patients treated with porcine skin xenografts L Scobie, V Padler-Karavani, L Bas-Bernardet, C Crossan, J Blaha, ... The Journal of Immunology 191 (6), 2907-2915, 2013 | 138 | 2013 |
Evidence for a novel human-specific xeno-auto-antibody response against vascular endothelium T Pham, CJ Gregg, F Karp, R Chow, V Padler-Karavani, H Cao, X Chen, ... Blood, The Journal of the American Society of Hematology 114 (25), 5225-5235, 2009 | 133 | 2009 |
Glycans in immune recognition and response R Amon, EM Reuven, SL Ben-Arye, V Padler-Karavani Carbohydrate research 389, 115-122, 2014 | 131 | 2014 |
Characterization of yeast V-ATPase mutants lacking Vph1p or Stv1p and the effect on endocytosis N Perzov, V Padler-Karavani, H Nelson, N Nelson Journal of experimental biology 205 (9), 1209-1219, 2002 | 106 | 2002 |
Aiming at the sweet side of cancer: aberrant glycosylation as possible target for personalized-medicine V Padler-Karavani Cancer letters 352 (1), 102-112, 2014 | 91 | 2014 |
Specific inactivation of two immunomodulatory SIGLEC genes during human evolution X Wang, N Mitra, I Secundino, K Banda, P Cruz, V Padler-Karavani, ... Proceedings of the National Academy of Sciences 109 (25), 9935-9940, 2012 | 87 | 2012 |
Rapid evolution of binding specificities and expression patterns of inhibitory CD33-related Siglecs in primates V Padler-Karavani, N Hurtado-Ziola, YC Chang, JL Sonnenburg, ... The FASEB Journal 28 (3), 1280, 2014 | 78 | 2014 |
Characterization of immunogenic Neu5Gc in bioprosthetic heart valves EM Reuven, S Leviatan Ben‐Arye, T Marshanski, ME Breimer, H Yu, ... Xenotransplantation 23 (5), 381-392, 2016 | 70 | 2016 |
Complexity and diversity of the mammalian sialome revealed by nidovirus virolectins MA Langereis, MJG Bakkers, L Deng, V Padler-Karavani, SJ Vervoort, ... Cell reports 11 (12), 1966-1978, 2015 | 69 | 2015 |
A simple method for assessment of human anti-Neu5Gc antibodies applied to Kawasaki disease V Padler-Karavani, AH Tremoulet, H Yu, X Chen, JC Burns, A Varki PLoS One 8 (3), e58443, 2013 | 68 | 2013 |
Glycosylated biotherapeutics: immunological effects of N-glycolylneuraminic acid S Yehuda, V Padler-Karavani Frontiers in immunology 11, 21, 2020 | 58 | 2020 |
Polyclonal human antibodies against glycans bearing red meat-derived non-human sialic acid N-glycolylneuraminic acid are stable, reproducible, complex and … AN Samraj, KA Bertrand, R Luben, Z Khedri, H Yu, D Nguyen, CJ Gregg, ... PLoS One 13 (6), e0197464, 2018 | 56 | 2018 |