A deep learning approach to antibiotic discovery JM Stokes, K Yang, K Swanson, W Jin, A Cubillos-Ruiz, NM Donghia, ... Cell 180 (4), 688-702. e13, 2020 | 1869 | 2020 |
Chemically induced proximity in biology and medicine BZ Stanton, EJ Chory, GR Crabtree Science 359 (6380), eaao5902, 2018 | 322 | 2018 |
Catalytic site remodelling of the DOT1L methyltransferase by selective inhibitors W Yu, EJ Chory, AK Wernimont, W Tempel, A Scopton, A Federation, ... Nature communications 3 (1), 1288, 2012 | 299 | 2012 |
Dynamics of BAF–Polycomb complex opposition on heterochromatin in normal and oncogenic states C Kadoch, RT Williams, JP Calarco, EL Miller, CM Weber, SMG Braun, ... Nature genetics 49 (2), 213-222, 2017 | 298 | 2017 |
Rapid and reversible epigenome editing by endogenous chromatin regulators SMG Braun, JG Kirkland, EJ Chory, D Husmann, JP Calarco, GR Crabtree Nature communications 8 (1), 560, 2017 | 167 | 2017 |
Nucleosome turnover regulates histone methylation patterns over the genome EJ Chory, JP Calarco, NA Hathaway, O Bell, DS Neel, GR Crabtree Molecular cell 73 (1), 61-72. e3, 2019 | 91 | 2019 |
RNA-responsive elements for eukaryotic translational control EM Zhao, AS Mao, H de Puig, K Zhang, ND Tippens, X Tan, FA Ran, ... Nature biotechnology 40 (4), 539-545, 2022 | 54 | 2022 |
Enabling high‐throughput biology with flexible open‐source automation EJ Chory, DW Gretton, EA DeBenedictis, KM Esvelt Molecular systems biology 17 (3), e9942, 2021 | 54 | 2021 |
Systematic molecular evolution enables robust biomolecule discovery EA DeBenedictis, EJ Chory, DW Gretton, B Wang, S Golas, KM Esvelt Nature Methods 19 (1), 55-64, 2022 | 50 | 2022 |
Separation of two phenotypically similar cell types via a single common marker in microfluidic channels DAL Vickers, EJ Chory, SK Murthy Lab on a Chip 12 (18), 3399-3407, 2012 | 25 | 2012 |
Structure-guided DOT1L probe optimization by label-free ligand displacement JS Yi, AJ Federation, J Qi, S Dhe-Paganon, M Hadler, X Xu, R St. Pierre, ... ACS chemical biology 10 (3), 667-674, 2015 | 22 | 2015 |
Chemical Inhibitors of a Selective SWI/SNF Function Synergize with ATR Inhibition in Cancer Cell Killing EJ Chory, JG Kirkland, CY Chang, VD D’Andrea, S Gourisankar, ... ACS Chemical Biology, 2020 | 18 | 2020 |
A high-throughput platform for feedback-controlled directed evolution EA DeBenedictis, EJ Chory, D Gretton, B Wang, K Esvelt BioRxiv, 2020.04. 01.021022, 2020 | 7 | 2020 |
Dynamic opposition of histone modifications AM Garzón-Porras, E Chory, BE Gryder ACS Chemical Biology 18 (4), 1027-1036, 2022 | 6 | 2022 |
High-throughput approaches to uncover synergistic drug combinations in leukemia EJ Chory, M Wang, M Ceribelli, AM Michalowska, S Golas, E Beck, ... SLAS Discovery 28 (4), 193-201, 2023 | 5 | 2023 |
Flexible open-source automation for robotic bioengineering EJ Chory, DW Gretton, EA Debenedictis, KM Esvelt bioRxiv, 2020 | 5 | 2020 |
Inhibition of a selective SWI/SNF function synergizes with ATR inhibitors in cancer cell killing EJ Chory, JG Kirkland, CY Chang, VD D’Andrea, S Gourinsankar, ... bioRxiv, 660456, 2019 | 5 | 2019 |
p38 Signaling and Receptor Recycling Events in a Microfluidic Endothelial Cell Adhesion Assay DAL Vickers, EJ Chory, MC Harless, SK Murthy Plos one 8 (6), e65828, 2013 | 4 | 2013 |
BAF complex modulating compounds and methods of using the same EJ Chory, GR Crabtree, EC Dykhuizen US Patent 11,267,809, 2022 | 1 | 2022 |
System for the directed evolution of biomolecules in multi-body complexes EJ Chory, K Esvelt, V Mukkamala US Patent App. 18/408,191, 2024 | | 2024 |