Cholesterol-mediated activation of acid sphingomyelinase disrupts autophagy in the retinal pigment epithelium KA Toops, LX Tan, Z Jiang, RA Radu, A Lakkaraju Molecular biology of the cell 26 (1), 1-14, 2015 | 94 | 2015 |
Mechanism of polarized lysosome exocytosis in epithelial cells J Xu, KA Toops, F Diaz, JM Carvajal-Gonzalez, D Gravotta, F Mazzoni, ... Journal of cell science 125 (24), 5937-5943, 2012 | 73 | 2012 |
A detailed three-step protocol for live imaging of intracellular traffic in polarized primary porcine RPE monolayers KA Toops, LX Tan, A Lakkaraju Experimental eye research 124, 74-85, 2014 | 69 | 2014 |
Aberrant early endosome biogenesis mediates complement activation in the retinal pigment epithelium in models of macular degeneration G Kaur, LX Tan, G Rathnasamy, N La Cunza, CJ Germer, KA Toops, ... Proceedings of the National Academy of Sciences 115 (36), 9014-9019, 2018 | 60 | 2018 |
Protective responses to sublytic complement in the retinal pigment epithelium LX Tan, KA Toops, A Lakkaraju Proceedings of the National Academy of Sciences 113 (31), 8789-8794, 2016 | 57 | 2016 |
Neuromuscular development in the absence of programmed cell death: phenotypic alteration of motoneurons and muscle RR Buss, TW Gould, J Ma, S Vinsant, D Prevette, A Winseck, KA Toops, ... Journal of Neuroscience 26 (52), 13413-13427, 2006 | 54 | 2006 |
Apolipoprotein E isoforms and AMD KA Toops, LX Tan, A Lakkaraju Retinal Degenerative Diseases: Mechanisms and Experimental Therapy, 3-9, 2016 | 37 | 2016 |
Reduction in diabetes‐induced craniofacial defects by maternal immune stimulation TC Hrubec, MR Prater, KA Toops, SD Holladay Birth Defects Research Part B: Developmental and Reproductive Toxicology 77 …, 2006 | 30 | 2006 |
Mitochondria-dependent phase separation of disease-relevant proteins drives pathological features of age-related macular degeneration N La Cunza, LX Tan, T Thamban, CJ Germer, G Rathnasamy, KA Toops, ... JCI insight 6 (9), 2021 | 28 | 2021 |
Novel roles for the radial spoke head protein 9 in neural and neurosensory cilia I Sedykh, JJ TeSlaa, RL Tatarsky, AN Keller, KA Toops, A Lakkaraju, ... Scientific reports 6 (1), 34437, 2016 | 23 | 2016 |
The effect of glial fibrillary acidic protein expression on neurite outgrowth from retinal explants in a permissive environment KA Toops, TL Hagemann, A Messing, RW Nickells BMC Research Notes 5, 1-9, 2012 | 20 | 2012 |
Should I stay or should I go? Trafficking of sub-lytic MAC in the retinal pigment epithelium A Lakkaraju, KA Toops, J Xu Retinal Degenerative Diseases: Mechanisms and Experimental Therapy, 267-274, 2014 | 18 | 2014 |
Hydrocortisone stimulates neurite outgrowth from mouse retinal explants by modulating macroglial activity KA Toops, C Berlinicke, DJ Zack, RW Nickells Investigative ophthalmology & visual science 53 (4), 2046-2061, 2012 | 18 | 2012 |
Modulation of diabetes‐induced palate defects by maternal immune stimulation TC Hrubec, KA Toops, SD Holladay The Anatomical Record: Advances in Integrative Anatomy and Evolutionary …, 2009 | 17 | 2009 |
Let’s play a game of chutes and ladders: Lysosome fusion with the epithelial plasma membrane KA Toops, A Lakkaraju Communicative & integrative biology 6 (4), e24474, 2013 | 14 | 2013 |
Apolipoprotein E isoform-specific phase transitions in the retinal pigment epithelium drive disease phenotypes in age-related macular degeneration N La Cunza, LX Tan, G Rathnasamy, T Thamban, CJ Germer, KA Toops, ... bioRxiv, 2020 | 2 | 2020 |
Use of inhibitors of acid sphingomyelinase to treat acquired and inherited retinal degenerations A Lakkaraju, KA Toops, LX Tan US Patent 10,124,008, 2018 | 2 | 2018 |
Differential regulation of organelle dynamics by tubulin acetylation in polarized epithelia. KA Toops, L Tan, A Lakkaraju MOLECULAR BIOLOGY OF THE CELL 25, 2014 | 1 | 2014 |
Photoreceptor outer segment phagocytosis couples lysosome biogenesis to autophagy in the retinal pigment epithelium J Xu, K Toops, A Lakkaraju Investigative Ophthalmology & Visual Science 54 (15), 1773-1773, 2013 | 1 | 2013 |
Interactions Between Apolipoprotein E Isoforms, Hepatic Lipase, and Lipoprotein Lipase In The Retinal Pigment Epithelium KA Toops, J Xu, A Lakkaraju Investigative Ophthalmology & Visual Science 53 (14), 6499-6499, 2012 | 1 | 2012 |