Systematic identification of conserved bacterial c-di-AMP receptor proteins RM Corrigan, I Campeotto, T Jeganathan, KG Roelofs, VT Lee, ... Proceedings of the National Academy of Sciences 110 (22), 9084-9089, 2013 | 314 | 2013 |
The second messenger c-di-AMP inhibits the osmolyte uptake system OpuC in Staphylococcus aureus CF Schuster, LE Bellows, T Tosi, I Campeotto, RM Corrigan, P Freemont, ... Science signaling 9 (441), ra81-ra81, 2016 | 109 | 2016 |
One-step design of a stable variant of the malaria invasion protein RH5 for use as a vaccine immunogen I Campeotto, A Goldenzweig, J Davey, L Barfod, JM Marshall, SE Silk, ... Proceedings of the National Academy of Sciences 114 (5), 998-1002, 2017 | 89 | 2017 |
Complex structure and biochemical characterization of the Staphylococcus aureus cyclic diadenylate monophosphate (c-di-AMP)-binding protein PstA, the founding member of a new … I Campeotto, Y Zhang, MG Mladenov, PS Freemont, A Gründling Journal of Biological Chemistry 290 (5), 2888-2901, 2015 | 57 | 2015 |
Reaction Mechanism of N-Acetylneuraminic Acid Lyase Revealed by a Combination of Crystallography, QM/MM Simulation, and Mutagenesis AD Daniels, I Campeotto, MW Van der Kamp, AH Bolt, CH Trinh, ... ACS chemical biology 9 (4), 1025-1032, 2014 | 50 | 2014 |
The Chlamydia effector TarP mimics the mammalian leucine-aspartic acid motif of paxillin to subvert the focal adhesion kinase during invasion T Thwaites, AT Nogueira, I Campeotto, AP Silva, SS Grieshaber, ... Journal of Biological Chemistry 289 (44), 30426-30442, 2014 | 42 | 2014 |
Structural insights into substrate specificity in variants of N-acetylneuraminic acid lyase produced by directed evolution I Campeotto, AH Bolt, TA Harman, C Dennis, CH Trinh, SEV Phillips, ... Journal of molecular biology 404 (1), 56-69, 2010 | 38 | 2010 |
Structural and mechanistic insight into the Listeria monocytogenes two-enzyme lipoteichoic acid synthesis system I Campeotto, MG Percy, JT MacDonald, A Förster, PS Freemont, ... Journal of Biological Chemistry 289 (41), 28054-28069, 2014 | 31 | 2014 |
Pathological macromolecular crystallographic data affected by twinning, partial-disorder and exhibiting multiple lattices for testing of data processing and refinement tools I Campeotto, A Lebedev, AMM Schreurs, LMJ Kroon-Batenburg, E Lowe, ... Scientific Reports 8 (1), 14876, 2018 | 16 | 2018 |
Structure of an Escherichia coli N-acetyl-d-neuraminic acid lyase mutant, E192N, in complex with pyruvate at 1.45 Å resolution I Campeotto, SB Carr, CH Trinh, AS Nelson, A Berry, SEV Phillips, ... Acta Crystallographica Section F: Structural Biology and Crystallization …, 2009 | 16 | 2009 |
Design of a basigin‐mimicking inhibitor targeting the malaria invasion protein RH5 S Warszawski, E Dekel, I Campeotto, JM Marshall, KE Wright, O Lyth, ... Proteins: Structure, Function, and Bioinformatics 88 (1), 187-195, 2020 | 9 | 2020 |
The structure of the cysteine-rich domain of Plasmodium falciparum P113 identifies the location of the RH5 binding site I Campeotto, F Galaway, S Mehmood, LK Barfod, D Quinkert, V Kotraiah, ... MBio 11 (5), 10.1128/mbio. 01566-20, 2020 | 7 | 2020 |
Jeganathan Tet al RM Corrigan, I Campeotto Systematic identification of conserved bacterial c-di-AMP receptor proteins …, 2013 | 7 | 2013 |
Protein-to-structure pipeline for ambient-temperature in situ crystallography at VMXi H Mikolajek, J Sanchez-Weatherby, J Sandy, RJ Gildea, I Campeotto, ... IUCrJ 10 (4), 2023 | 6 | 2023 |
Complex structure and biochemical characterization of the Staphylococcus aureus cyclic di-AMP binding protein PstA, the founding member of a new signal transduction protein family I Campeotto, Y Zhang, MG Mladenov, PS Freemont, A Gründling J Biol Chem 290, 2888-2901, 2015 | 5 | 2015 |
Preclinical development of a stabilized RH5 virus-like particle vaccine that induces improved anti-malarial antibodies LDW King, D Pulido, JR Barrett, H Davies, D Quinkert, AM Lias, SE Silk, ... BioRxiv, 2024.01. 04.574181, 2024 | 2 | 2024 |
Hijacking nature—new approaches to unravel enzyme mechanisms and engineer improved biocatalysts I Campeotto, CG Acevedo‐Rocha EMBO reports 14 (4), 299-301, 2013 | 1 | 2013 |
The Potential of Plant-Produced Virus-like Particle Vaccines for African Horse Sickness and Other Equine Orbiviruses KG Pitchers, OD Boakye, I Campeotto, JM Daly Pathogens 13 (6), 458, 2024 | | 2024 |
Resolving multiple conformations of a sub-80 kDa Chagas vaccine candidate by cryo-EM led integrative approach I Campeotto, S Batra, T Ragan, A Frank, M Kaplan, C Lancey, ... | | 2024 |
Open and closed conformations of a sub-80 kDa Chagas vaccine candidate defined by a cryo-EM led integrative approach S Batra, TJ Ragan, AM Frank, M Kaplan, C Lancey, M Assadipapari, ... bioRxiv, 2024.03. 26.586384, 2024 | | 2024 |