NINJ1 mediates plasma membrane rupture during lytic cell death N Kayagaki, OS Kornfeld, BL Lee, IB Stowe, K O’Rourke, Q Li, ... Nature 591 (7848), 131-136, 2021 | 450 | 2021 |
Correcting mitochondrial fusion by manipulating mitofusin conformations A Franco, RN Kitsis, JA Fleischer, E Gavathiotis, OS Kornfeld, G Gong, ... Nature 540 (7631), 74-79, 2016 | 229 | 2016 |
Mitochondrial reactive oxygen species at the heart of the matter: new therapeutic approaches for cardiovascular diseases OS Kornfeld, S Hwang, MH Disatnik, CH Chen, N Qvit, D Mochly-Rosen Circulation research 116 (11), 1783-1799, 2015 | 197 | 2015 |
Caspase-11 auto-proteolysis is crucial for noncanonical inflammasome activation BL Lee, IB Stowe, A Gupta, OS Kornfeld, M Roose-Girma, K Anderson, ... Journal of Experimental Medicine 215 (9), 2279-2288, 2018 | 146 | 2018 |
IRF2 transcriptionally induces GSDMD expression for pyroptosis N Kayagaki, BL Lee, IB Stowe, OS Kornfeld, K O'Rourke, KM Mirrashidi, ... Science signaling 12 (582), eaax4917, 2019 | 144 | 2019 |
Interaction of mitochondrial fission factor with dynamin related protein 1 governs physiological mitochondrial function in vivo OS Kornfeld, N Qvit, B Haileselassie, M Shamloo, P Bernardi, ... Scientific reports 8 (1), 14034, 2018 | 67 | 2018 |
Inhibiting membrane rupture with NINJ1 antibodies limits tissue injury N Kayagaki, IB Stowe, K Alegre, I Deshpande, S Wu, Z Lin, OS Kornfeld, ... Nature 618 (7967), 1072-1077, 2023 | 54 | 2023 |
The entangled ER-mitochondrial axis as a potential therapeutic strategy in neurodegeneration: a tangled duo unchained AU Joshi, OS Kornfeld, D Mochly-Rosen Cell Calcium 60 (3), 218-234, 2016 | 52 | 2016 |
Genetic targeting of Card19 is linked to disrupted NINJ1 expression, impaired cell lysis, and increased susceptibility to Yersinia infection E Bjanes, RG Sillas, R Matsuda, B Demarco, T Fettrelet, AA DeLaney, ... PLoS Pathogens 17 (10), e1009967, 2021 | 30 | 2021 |
Engineered Substrate‐Specific Delta PKC Antagonists to Enhance Cardiac Therapeutics N Qvit, OS Kornfeld, D Mochly‐Rosen Angewandte Chemie 128 (50), 15901-15908, 2016 | 20 | 2016 |
Development of a Backbone Cyclic Peptide Library as Potential Antiparasitic Therapeutics Using Microwave Irradiation N Qvit, OS Kornfeld Journal of Visualized Experiments, e53589, 2016 | 13 | 2016 |
Epigenetic and transcriptional control of gasdermins C Cadena, OS Kornfeld, BL Lee, N Kayagaki Seminars in Immunology 70, 101841, 2023 | 3 | 2023 |
Highly multiplexed, image-based pooled screens in primary cells and tissues with PerturbView T Kudo, AM Meireles, R Moncada, Y Chen, P Wu, J Gould, X Hu, ... bioRxiv, 2023.12. 26.573143, 2023 | 1 | 2023 |
A novel pharmacological modulator abrogates physiological mitochondrial fission though specifically inhibiting the Mff‐Drp1 protein‐protein interaction OS Kornfeld, N Qvit, M Shamloo, D Mochly‐Rosen The FASEB Journal 32, 543.21-543.21, 2018 | | 2018 |
Novel Pharmacological Modulators of Mitochondrial Function in Cell Physiology and Pathology OS Kornfeld Stanford University, 2018 | | 2018 |
A novel pharmacological tool blocks physiological mitochondrial fission through specifically inhibiting the Mff-Drp1 protein-protein interaction. OS Kornfeld, N Qvit, M Monbureau, M Halpain, M Shamloo, ... MOLECULAR BIOLOGY OF THE CELL 28, 2017 | | 2017 |
Utilizing a novel peptide Inhibitor to modulate mitochondrial dynamics and investigate Drp1's physiological roles. OS Kornfeld, N Qvit, M Disatnik, M Monbureau, M Halpain, A Evans, ... MOLECULAR BIOLOGY OF THE CELL 26, 2015 | | 2015 |