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Erden Eren
Erden Eren
Denali Therapeutics
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Early increase of CSF sTREM2 in Alzheimer’s disease is associated with tau related-neurodegeneration but not with amyloid-β pathology
M Suárez-Calvet, E Morenas-Rodríguez, G Kleinberger, K Schlepckow, ...
Molecular neurodegeneration 14, 1-14, 2019
2212019
CSF progranulin increases in the course of Alzheimer's disease and is associated with sTREM 2, neurodegeneration and cognitive decline
M Suárez‐Calvet, A Capell, MÁ Araque Caballero, E Morenas‐Rodríguez, ...
EMBO molecular medicine 10 (12), e9712, 2018
892018
Astrocyte-and neuron-derived extracellular vesicles from Alzheimer’s disease patients effect complement-mediated neurotoxicity
CJ Nogueras-Ortiz, V Mahairaki, F Delgado-Peraza, D Das, K Avgerinos, ...
Cells 9 (7), 1618, 2020
802020
Sulforaphane inhibits lipopolysaccharide-induced inflammation, cytotoxicity, oxidative stress, and miR-155 expression and switches to Mox phenotype through activating …
E Eren, KU Tufekci, KB Isci, B Tastan, K Genc, S Genc
Frontiers in immunology 9, 36, 2018
782018
Extracellular vesicle biomarkers for cognitive impairment in Parkinson’s disease
J Blommer, T Pitcher, M Mustapic, E Eren, PJ Yao, MP Vreones, ...
Brain 146 (1), 195-208, 2023
602023
Extracellular vesicle biomarkers of Alzheimer's disease associated with sub‐clinical cognitive decline in late middle age
E Eren, JFV Hunt, M Shardell, S Chawla, J Tran, J Gu, NM Vogt, ...
Alzheimer's & Dementia 16 (9), 1293-1304, 2020
602020
Mitochondrial RNA in Alzheimer’s disease circulating extracellular vesicles
KM Kim, Q Meng, O Perez de Acha, M Mustapic, A Cheng, E Eren, ...
Frontiers in cell and developmental biology 8, 581882, 2020
492020
Validation of a quantitative cerebrospinal fluid alpha-synuclein assay in a European-wide interlaboratory study
N Kruse, S Persson, D Alcolea, JMC Bahl, I Baldeiras, E Capello, ...
Neurobiology of aging 36 (9), 2587-2596, 2015
352015
Mitochondrial electron transport chain protein abnormalities detected in plasma extracellular vesicles in Alzheimer’s disease
PJ Yao, E Eren, EJ Goetzl, D Kapogiannis
Biomedicines 9 (11), 1587, 2021
312021
Neuronal-derived EV biomarkers track cognitive decline in Alzheimer’s disease
E Eren, JM Leoutsakos, J Troncoso, CG Lyketsos, ES Oh, D Kapogiannis
Cells 11 (3), 436, 2022
272022
Mitochondrial protrusions in neuronal cells
PJ Yao, E Eren, RS Petralia, JW Gu, YX Wang, D Kapogiannis
Iscience 23 (9), 2020
202020
MicroRNA exocytosis by large dense-core vesicle fusion
A Gümürdü, R Yildiz, E Eren, G Karakülah, T Ünver, Ş Genç, Y Park
Scientific reports 7 (1), 45661, 2017
202017
Synaptic proteins in neuron-derived extracellular vesicles as biomarkers for Alzheimer’s disease: novel methodology and clinical proof of concept
E Eitan, T Thornton-Wells, K Elgart, E Erden, E Gershun, A Levine, ...
Extracellular vesicles and circulating nucleic acids 4 (1), 133, 2023
172023
I. Alzheimer's Disease Neuroimaging (2019).“Early increase of CSF sTREM2 in Alzheimer's disease is associated with tau related-neurodegeneration but not with amyloid-beta …
M Suarez-Calvet, E Morenas-Rodriguez, G Kleinberger, K Schlepckow, ...
Mol Neurodegener 14 (1), 1, 0
14
Improved cerebrospinal fluid-based discrimination between Alzheimer’s disease patients and controls after correction for ventricular volumes
LJC Van Waalwijk Van Doorn, JD Gispert, HB Kuiperij, JAHR Claassen, ...
Journal of Alzheimer's Disease 56 (2), 543-555, 2017
112017
Inhibiting tau-induced elevated nSMase2 activity and ceramides is therapeutic in an Alzheimer’s disease mouse model
C Tallon, BJ Bell, MM Malvankar, P Deme, C Nogueras-Ortiz, E Eren, ...
Translational Neurodegeneration 12 (1), 56, 2023
52023
Novel modification of Luminex assay for characterization of extracellular vesicle populations in biofluids
OV Volpert, E Gershun, K Elgart, V Kalia, H Wu, AA Baccarelli, E Eren, ...
BioRxiv, 2022.01. 12.475897, 2022
52022
Single‐extracellular vesicle (EV) analyses validate the use of L1 Cell Adhesion Molecule (L1CAM) as a reliable biomarker of neuron‐derived EVs
CJ Nogueras‐Ortiz, E Eren, P Yao, E Calzada, C Dunn, O Volpert, ...
Journal of Extracellular Vesicles 13 (6), e12459, 2024
42024
Inhibiting tau-induced elevated nSMase2 activity and ceramides is therapeutic in murine Alzheimer’s disease
C Tallon, BJ Bell, MM Malvankar, P Deme, C Nogueras-Ortiz, E Eren, ...
Research Square, 2023
32023
Examination of IL-1 beta level as an inflammasome marker in Alzheimer's disease
O Bulut, A Tanburoglu, G Boluk, N Demir, E Eren, U Vurgun, S Genc, ...
22019
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