| Preclinical evaluation of a potent novel DNA-dependent protein kinase inhibitor NU7441 Y Zhao, HD Thomas, MA Batey, IG Cowell, CJ Richardson, RJ Griffin, ... Cancer research 66 (10), 5354-5362, 2006 | 532 | 2006 |
| Mammalian chromodomain proteins: their role in genome organisation and expression DO Jones, IG Cowell, PB Singh Bioessays 22 (2), 124-137, 2000 | 369 | 2000 |
| Heterochromatin, HP1 and methylation at lysine 9 of histone H3 in animals IG Cowell, R Aucott, SK Mahadevaiah, PS Burgoyne, N Huskisson, ... Chromosoma 111, 22-36, 2002 | 317 | 2002 |
| γH2AX foci form preferentially in euchromatin after ionising-radiation IG Cowell, NJ Sunter, PB Singh, CA Austin, BW Durkacz, MJ Tilby PloS one 2 (10), e1057, 2007 | 281 | 2007 |
| Repression versus activation in the control of gene transcription IG Cowell Trends in biochemical sciences 19 (1), 38-42, 1994 | 266 | 1994 |
| Transcriptional repression by a novel member of the bZIP family of transcription factors IG Cowell, A Skinner, HC Hurst Molecular and cellular biology 12 (7), 3070-3077, 1992 | 240 | 1992 |
| Model for MLL translocations in therapy-related leukemia involving topoisomerase IIβ-mediated DNA strand breaks and gene proximity IG Cowell, Z Sondka, K Smith, KC Lee, CM Manville, ... Proceedings of the National Academy of Sciences 109 (23), 8989-8994, 2012 | 198 | 2012 |
| The structure of the human glutathione S-transferase π gene IG Cowell, KH Dixon, SE Pemble, B Ketterer, JB Taylor Biochemical Journal 255 (1), 79-83, 1988 | 195 | 1988 |
| E4BP4/NFIL3, a PAR‐related bZIP factor with many roles IG Cowell Bioessays 24 (11), 1023-1029, 2002 | 182 | 2002 |
| The Ki‐67 protein interacts with members of the heterochromatin protein 1 (HP1) family: a potential role in the regulation of higher‐order chromatin structure T Scholzen, E Endl, C Wohlenberg, S van der Sar, IG Cowell, J Gerdes, ... The Journal of Pathology: A Journal of the Pathological Society of Great …, 2002 | 169 | 2002 |
| Conservation of heterochromatin protein 1 function G Wang, A Ma, C Chow, D Horsley, NR Brown, IG Cowell, PB Singh Molecular and cellular biology 20 (18), 6970-6983, 2000 | 153 | 2000 |
| Dynamic associations of heterochromatin protein 1 with the nuclear envelope N Kourmouli, PA Theodoropoulos, G Dialynas, A Bakou, AS Politou, ... The EMBO journal 19 (23), 6558-6568, 2000 | 149 | 2000 |
| Mechanism of generation of therapy related leukemia in response to anti-topoisomerase II agents IG Cowell, CA Austin International journal of environmental research and public health 9 (6 …, 2012 | 147 | 2012 |
| NK314, a topoisomerase II inhibitor that specifically targets the α isoform E Toyoda, S Kagaya, IG Cowell, A Kurosawa, K Kamoshita, K Nishikawa, ... Journal of Biological Chemistry 283 (35), 23711-23720, 2008 | 146 | 2008 |
| DNA-dependent protein kinase is a therapeutic target and an indicator of poor prognosis in B-cell chronic lymphocytic leukemia E Willmore, SL Elliott, T Mainou-Fowler, GP Summerfield, GH Jackson, ... Clinical cancer research 14 (12), 3984-3992, 2008 | 134 | 2008 |
| Transcriptional repression by the human bZIP factor E4BP4: definition of a minimal repression domain IG Cowell, HC Hurst Nucleic acids research 22 (1), 59-65, 1994 | 103 | 1994 |
| TOP2B: the first thirty years CA Austin, KC Lee, RL Swan, MM Khazeem, CM Manville, P Cridland, ... International Journal of Molecular Sciences 19 (9), 2765, 2018 | 101 | 2018 |
| Sensitization of breast carcinoma cells to ionizing radiation by small molecule inhibitors of DNA-dependent protein kinase and ataxia telangiectsia mutated IG Cowell, BW Durkacz, MJ Tilby Biochemical pharmacology 71 (1-2), 13-20, 2005 | 91 | 2005 |
| MRE11 facilitates the removal of human topoisomerase II complexes from genomic DNA KC Lee, K Padget, H Curtis, IG Cowell, D Moiani, Z Sondka, NJ Morris, ... Biology open 1 (9), 863-873, 2012 | 86 | 2012 |
| Human topoisomerase IIα and IIβ interact with the C-terminal region of p53 IG Cowell, AL Okorokov, SA Cutts, K Padget, M Bell, J Milner, CA Austin Experimental cell research 255 (1), 86-94, 2000 | 74 | 2000 |
