Structural basis for recognition of urokinase-type plasminogen activator by plasminogen activator inhibitor-1 Z Lin, L Jiang, C Yuan, JK Jensen, X Zhang, Z Luo, BC Furie, B Furie, ... Journal of biological chemistry 286 (9), 7027-7032, 2011 | 72 | 2011 |
Oleanolic acid derivative NPLC441 potently stimulates glucose transport in 3T3-L1 adipocytes via a multi-target mechanism Z Lin, Y Zhang, Y Zhang, H Shen, L Hu, H Jiang, X Shen Biochemical pharmacology 76 (10), 1251-1262, 2008 | 52 | 2008 |
Structural basis for therapeutic intervention of uPA/uPAR system J Chi Ki Ngo, L Jiang, Z Lin, C Yuan, Z Chen, X Zhang, H Yu, J Wang, ... Current drug targets 12 (12), 1729-1743, 2011 | 49 | 2011 |
Structural insight into inactivation of plasminogen activator inhibitor-1 by a small-molecule antagonist Z Lin, JK Jensen, Z Hong, X Shi, L Hu, PA Andreasen, M Huang Chemistry & biology 20 (2), 253-261, 2013 | 47 | 2013 |
Danshen extract 15, 16-dihydrotanshinone I functions as a potential modulator against metabolic syndrome through multi-target pathways Q Liu, Y Zhang, Z Lin, H Shen, L Chen, L Hu, H Jiang, X Shen The Journal of steroid biochemistry and molecular biology 120 (4-5), 155-163, 2010 | 38 | 2010 |
Substrate-specific activation of the mitotic kinase Bub1 through intramolecular autophosphorylation and kinetochore targeting Z Lin, L Jia, DR Tomchick, X Luo, H Yu Structure 22 (11), 1616-1627, 2014 | 33 | 2014 |
A specific plasminogen activator inhibitor‐1 antagonist derived from inactivated urokinase L Gong, V Proulle, C Fang, Z Hong, Z Lin, M Liu, G Xue, C Yuan, L Lin, ... Journal of cellular and molecular medicine 20 (10), 1851-1860, 2016 | 29 | 2016 |
Structural basis of sequence-specific Holliday junction cleavage by MOC1 H Lin, D Zhang, K Zuo, C Yuan, J Li, M Huang, Z Lin Nature chemical biology 15 (12), 1241-1248, 2019 | 23 | 2019 |
Punicalagin as an allosteric NSP13 helicase inhibitor potently suppresses SARS-CoV-2 replication in vitro L Lu, Y Peng, H Yao, Y Wang, J Li, Y Yang, Z Lin Antiviral Research 206, 105389, 2022 | 22 | 2022 |
A hypoxia-activated prodrug conjugated with a BODIPY-based photothermal agent for imaging-guided chemo-photothermal combination therapy DC Yang, LF Wen, L Du, CM Luo, ZY Lu, JY Liu, Z Lin ACS Applied Materials & Interfaces 14 (36), 40546-40558, 2022 | 20 | 2022 |
Singlet oxygen-responsive polymeric nanomedicine for light-controlled drug release and image-guided photodynamic–chemo combination therapy DC Yang, S Wang, XL Weng, HX Zhang, JY Liu, Z Lin ACS Applied Materials & Interfaces 13 (29), 33905-33914, 2021 | 15 | 2021 |
Design, synthesis, and SAR of embelin analogues as the inhibitors of PAI-1 (plasminogen activator inhibitor-1) F Chen, G Zhang, Z Hong, Z Lin, M Lei, M Huang, L Hu Bioorganic & Medicinal Chemistry Letters 24 (10), 2379-2382, 2014 | 15 | 2014 |
Discovery of a novel Aurora B inhibitor GSK650394 with potent anticancer and anti-aspergillus fumigatus dual efficacies in vitro Y He, W Fu, L Du, H Yao, Z Hua, J Li, Z Lin Journal of Enzyme Inhibition and Medicinal Chemistry 37 (1), 109-117, 2022 | 10 | 2022 |
A promising strategy for synergistic cancer therapy by integrating a photosensitizer into a hypoxia-activated prodrug DC Yang, XZ Yang, CM Luo, LF Wen, JY Liu, Z Lin European Journal of Medicinal Chemistry 243, 114749, 2022 | 9 | 2022 |
Crystal structure of the human MUS81-EME2 complex Z Hua, Q Fang, D Zhang, Z Luo, C Yuan, Z Lin Structure 30 (5), 743-752. e3, 2022 | 7 | 2022 |
Marine natural product des-O-methyllasiodiplodin effectively lowers the blood glucose level in db/db mice via ameliorating inflammation R Zhou, Z Lin, C Jiang, J Gong, L Chen, Y Guo, X Shen Acta Pharmacologica Sinica 34 (10), 1325-1336, 2013 | 7 | 2013 |
Identification of small-molecule inhibitors of human MUS81-EME1/2 by FRET-based high-throughput screening X Zhang, X Chen, L Lu, Q Fang, C Liu, Z Lin Bioorganic & Medicinal Chemistry 90, 117383, 2023 | 4 | 2023 |
Molecular basis of stepwise cyclic tetra-adenylate cleavage by the type III CRISPR ring nuclease Crn1/Sso2081 L Du, D Zhang, Z Luo, Z Lin Nucleic Acids Research 51 (5), 2485-2495, 2023 | 4 | 2023 |
Biochemical and structural characterization of the Holliday junction resolvase RuvC from Pseudomonas aeruginosa Y Hu, Y He, Z Lin Biochemical and Biophysical Research Communications 525 (2), 265-271, 2020 | 4 | 2020 |
Identification of small-molecule inhibitors of the DNA repair proteins RuvAB from Pseudomonas aeruginosa L Dai, L Lu, X Zhang, J Wu, J Li, Z Lin Bioorganic & Medicinal Chemistry 73, 117022, 2022 | 3 | 2022 |