A comprehensive assessment of RNA-seq accuracy, reproducibility and information content by the Sequencing Quality Control Consortium Nature biotechnology 32 (9), 903-914, 2014 | 849 | 2014 |
Alternative (non-animal) methods for cosmetics testing: current status and future prospects—2010 S Adler, D Basketter, S Creton, O Pelkonen, J Van Benthem, V Zuang, ... Archives of toxicology 85, 367-485, 2011 | 639 | 2011 |
The concordance between RNA-seq and microarray data depends on chemical treatment and transcript abundance C Wang, B Gong, PR Bushel, J Thierry-Mieg, D Thierry-Mieg, J Xu, ... Nature biotechnology 32 (9), 926-932, 2014 | 537 | 2014 |
SFTG international collaborative study on in vitro micronucleus test: II. Using human lymphocytes MG Clare, G Lorenzon, LC Akhurst, D Marzin, J van Delft, R Montero, ... Mutation Research/Genetic Toxicology and Environmental Mutagenesis 607 (1 …, 2006 | 396 | 2006 |
Comparison of HepG2 and HepaRG by whole-genome gene expression analysis for the purpose of chemical hazard identification DGJ Jennen, C Magkoufopoulou, HB Ketelslegers, MHM van Herwijnen, ... Toxicological sciences 115 (1), 66-79, 2010 | 262 | 2010 |
Discrimination of genotoxic from non-genotoxic carcinogens by gene expression profiling JHM Van Delft, E Van Agen, SGJ Van Breda, MH Herwijnen, YCM Staal, ... Carcinogenesis 25 (7), 1265-1276, 2004 | 177 | 2004 |
The importance of polymerization and galloylation for the antiproliferative properties of procyanidin‐rich natural extracts D Lizarraga, C Lozano, JJ Briedé, JH Van Delft, S Touriño, JJ Centelles, ... The FEBS Journal 274 (18), 4802-4811, 2007 | 116 | 2007 |
Biological monitoring the exposure to polycyclic aromatic hydrocarbons of coke oven workers in relation to smoking and genetic polymorphisms for GSTM1 and GSTT1 JHM van Delft, MJST Steenwinkel, JG van Asten, N de Vogel, ... The Annals of occupational hygiene 45 (5), 395-408, 2001 | 116 | 2001 |
An untargeted multi-technique metabolomics approach to studying intracellular metabolites of HepG2 cells exposed to 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin A Ruiz-Aracama, A Peijnenburg, J Kleinjans, D Jennen, J van Delft, ... Bmc Genomics 12, 1-19, 2011 | 106 | 2011 |
Binary PAH mixtures cause additive or antagonistic effects on gene expression but synergistic effects on DNA adduct formation YCM Staal, DGAJ Hebels, MH Van Herwijnen, RWH Gottschalk, ... Carcinogenesis 28 (12), 2632-2640, 2007 | 105 | 2007 |
Meeting report: Validation of toxicogenomics-based test systems: ECVAM–ICCVAM/NICEATM considerations for regulatory use R Corvi, HJ Ahr, S Albertini, DH Blakey, L Clerici, S Coecke, GR Douglas, ... Environmental health perspectives 114 (3), 420-429, 2006 | 105 | 2006 |
A transcriptomics-based in vitro assay for predicting chemical genotoxicity in vivo C Magkoufopoulou, SMH Claessen, M Tsamou, DGJ Jennen, ... Carcinogenesis 33 (7), 1421-1429, 2012 | 104 | 2012 |
Differential gene expression in human peripheral blood mononuclear cells induced by cigarette smoke and its constituents DM van Leeuwen, RWH Gottschalk, MH van Herwijnen, EJ Moonen, ... Toxicological Sciences 86 (1), 200-210, 2005 | 100 | 2005 |
Proteomics investigations of drug-induced hepatotoxicity in HepG2 cells A Van Summeren, J Renes, FG Bouwman, JP Noben, JHM van Delft, ... Toxicological Sciences 120 (1), 109-122, 2011 | 93 | 2011 |
Assessing the metabolic competence of sandwich-cultured mouse primary hepatocytes K Mathijs, AS Kienhuis, KJJ Brauers, DGJ Jennen, A Lahoz, ... Drug Metabolism and Disposition 37 (6), 1305-1311, 2009 | 90 | 2009 |
Discrimination for genotoxic and nongenotoxic carcinogens by gene expression profiling in primary mouse hepatocytes improves with exposure time K Mathijs, KJJ Brauers, DGJ Jennen, A Boorsma, MHM Van Herwijnen, ... Toxicological sciences 112 (2), 374-384, 2009 | 86 | 2009 |
Cigarette smoke-induced differential gene expression in blood cells from monozygotic twin pairs DM Leeuwen, E Agen, RWH Gottschalk, R Vlietinck, M Gielen, ... Carcinogenesis 28 (3), 691-697, 2007 | 84 | 2007 |
Comparison of supervised clustering methods to discriminate genotoxic from non-genotoxic carcinogens by gene expression profiling JHM Van Delft, E Van Agen, SGJ Van Breda, MH Herwijnen, YCM Staal, ... Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 575 (1 …, 2005 | 84 | 2005 |
Prenatal exposure to polychlorinated biphenyls and dioxins is associated with increased risk of wheeze and infections in infants SB Stølevik, UC Nygaard, E Namork, M Haugen, HE Kvalem, HM Meltzer, ... Food and chemical toxicology 49 (8), 1843-1848, 2011 | 82 | 2011 |
Classification of hepatotoxicants using HepG2 cells: A proof of principle study WFPM Van den Hof, MLJ Coonen, M van Herwijnen, K Brauers, ... Chemical research in toxicology 27 (3), 433-442, 2014 | 79 | 2014 |