Design of protein-binding proteins from the target structure alone L Cao, B Coventry, I Goreshnik, B Huang, W Sheffler, JS Park, KM Jude, ... Nature 605 (7910), 551-560, 2022 | 299 | 2022 |
Application of 3D cultured multicellular spheroid tumor models in tumor-targeted drug delivery system research BW Huang, JQ Gao Journal of controlled release 270, 246-259, 2018 | 159 | 2018 |
Improving de novo protein binder design with deep learning NR Bennett, B Coventry, I Goreshnik, B Huang, A Allen, D Vafeados, ... Nature Communications 14 (1), 2625, 2023 | 134 | 2023 |
Hypoxia-tropic protein nanocages for modulation of tumor-and chemotherapy-associated hypoxia X Huang, J Zhuang, SW Chung, B Huang, G Halpert, K Negron, X Sun, ... Acs Nano 13 (1), 236-247, 2018 | 74 | 2018 |
Atomically accurate de novo design of single-domain antibodies NR Bennett, JL Watson, RJ Ragotte, AJ Borst, DL See, C Weidle, ... bioRxiv, 2024 | 20 | 2024 |
Robust de novo design of protein binding proteins from target structural information alone L Cao, B Coventry, I Goreshnik, B Huang, JS Park, KM Jude, I Marković, ... BioRxiv, 2021.09. 04.459002, 2021 | 15 | 2021 |
Randomized gates eliminate bias in sort‐seq assays BL Trippe, B Huang, EA DeBenedictis, B Coventry, N Bhattacharya, ... Protein Science 31 (9), e4401, 2022 | 9 | 2022 |
Designed endocytosis-triggering proteins mediate targeted degradation B Huang, M Abedi, G Ahn, B Coventry, I Sappington, R Wang, ... BioRxiv, 2023 | 6 | 2023 |
Transcriptome-wide elucidation of liposomal formulations for anticancer drug delivery Y Li, M Wang, BW Huang, Y Ping, J You, JQ Gao International Journal of Nanomedicine, 8557-8572, 2017 | 5 | 2017 |
Design of High Affinity Binders to Convex Protein Target Sites W Yang, DR Hicks, A Ghosh, TA Schwartze, B Conventry, I Goreshnik, ... bioRxiv, 2024 | 3 | 2024 |
De novo designed Hsp70 activator dissolves intracellular condensates JZ Zhang, N Greenwood, J Hernandez, JT Cuperus, B Huang, BD Ryder, ... bioRxiv, 2023 | 2 | 2023 |
De novo design of miniprotein antagonists of cytokine storm inducers B Huang, B Coventry, MT Borowska, DC Arhontoulis, M Exposit, M Abedi, ... Nature Communications 15 (1), 7064, 2024 | 1 | 2024 |
Engineered receptors for soluble cell-to-cell communication DI Piraner, MH Abedi, MJ Duran Gonzalez, A Chazin-Gray, I Zhu, ... bioRxiv, 2024.09. 17.613377, 2024 | 1 | 2024 |
Designed endocytosis-inducing proteins degrade targets and amplify signals B Huang, M Abedi, G Ahn, B Coventry, I Sappington, C Tang, R Wang, ... Nature, 1-9, 2024 | | 2024 |
De Novo Design of Integrin α5β1 Modulating Proteins for Regenerative Medicine X Wang, J Guillem-Marti, S Kumar, DS Lee, D Cabrerizo-Aguado, ... bioRxiv, 2024.06. 21.600123, 2024 | | 2024 |
Target-conditioned diffusion generates potent TNFR superfamily antagonists and agonists M Gloegl, A Krishnakumar, R Ragotte, I Goreshnik, B Coventry, AK Bera, ... bioRxiv, 2024.09. 13.612773, 2024 | | 2024 |
Multispectral live-cell imaging with uncompromised spatiotemporal resolution A Kumar, KE McNally, Y Zhang, A Haslett-Saunders, X Wang, ... bioRxiv, 2024.06. 12.597784, 2024 | | 2024 |
HYBRID TUMOR PENETRATING FERRITIN NANOCAGES AS A HYPOXIA TARGETING NANOCARRIER FOR CANCER TREATMENT B Huang Johns Hopkins University, 2019 | | 2019 |
Transcriptome-wide elucidation of liposomal formulations for anticancer drug delivery BW Huang, Y Ping, J You, JQ Gao, Y Li, M Wang | | 2017 |