Indirubins Inhibit Glycogen Synthase Kinase-3β and CDK5/P25, Two Protein Kinases Involved in Abnormal Tau Phosphorylation in Alzheimer's Disease: A PROPERTY COMMON TO MOST … S Leclerc, M Garnier, R Hoessel, D Marko, JA Bibb, GL Snyder, ... Journal of Biological Chemistry 276 (1), 251-260, 2001 | 928 | 2001 |
PKC-α regulates cardiac contractility and propensity toward heart failure JC Braz, K Gregory, A Pathak, W Zhao, B Sahin, R Klevitsky, TF Kimball, ... Nature medicine 10 (3), 248-254, 2004 | 771 | 2004 |
Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons JA Bibb, GL Snyder, A Nishi, Z Yan, L Meijer, AA Fienberg, LH Tsai, ... Nature 402 (6762), 669-671, 1999 | 670 | 1999 |
Effects of chronic exposure to cocaine are regulated by the neuronal protein Cdk5 JA Bibb, J Chen, JR Taylor, P Svenningsson, A Nishi, GL Snyder, Z Yan, ... Nature 410 (6826), 376-380, 2001 | 572 | 2001 |
Paullones are potent inhibitors of glycogen synthase kinase‐3β and cyclin‐dependent kinase 5/p25 M Leost, C Schultz, A Link, YZ Wu, J Biernat, EM Mandelkow, JA Bibb, ... European journal of biochemistry 267 (19), 5983-5994, 2000 | 497 | 2000 |
Cyclin-dependent kinase 5 governs learning and synaptic plasticity via control of NMDAR degradation AH Hawasli, DR Benavides, C Nguyen, JW Kansy, K Hayashi, ... Nature neuroscience 10 (7), 880-886, 2007 | 361 | 2007 |
The hypothalamic neuropeptide melanin-concentrating hormone acts in the nucleus accumbens to modulate feeding behavior and forced-swim performance D Georgescu, RM Sears, JD Hommel, M Barrot, CA Bolanos, DJ Marsh, ... Journal of Neuroscience 25 (11), 2933-2940, 2005 | 355 | 2005 |
Severe deficiencies in dopamine signaling in presymptomatic Huntington's disease mice JA Bibb, Z Yan, P Svenningsson, GL Snyder, VA Pieribone, A Horiuchi, ... Proceedings of the National Academy of Sciences 97 (12), 6809-6814, 2000 | 345 | 2000 |
Extrasynaptic NMDA receptors couple preferentially to excitotoxicity via calpain-mediated cleavage of STEP J Xu, P Kurup, Y Zhang, SM Goebel-Goody, PH Wu, AH Hawasli, ... Journal of Neuroscience 29 (29), 9330-9343, 2009 | 335 | 2009 |
Cocaine-induced proliferation of dendritic spines in nucleus accumbens is dependent on the activity of cyclin-dependent kinase-5 SD Norrholm, JA Bibb, EJ Nestler, CC Ouimet, JR Taylor, P Greengard Neuroscience 116 (1), 19-22, 2003 | 305 | 2003 |
Amplification of dopaminergic signaling by a positive feedback loop A Nishi, JA Bibb, GL Snyder, H Higashi, AC Nairn, P Greengard Proceedings of the National Academy of Sciences 97 (23), 12840-12845, 2000 | 285 | 2000 |
Involvement of DARPP-32 phosphorylation in the stimulant action of caffeine M Lindskog, P Svenningsson, L Pozzi, Y Kim, AA Fienberg, JA Bibb, ... Nature 418 (6899), 774-778, 2002 | 208 | 2002 |
The role of Cdk5 in neuroendocrine thyroid cancer K Pozo, E Castro-Rivera, C Tan, F Plattner, G Schwach, V Siegl, D Meyer, ... Cancer cell 24 (4), 499-511, 2013 | 189 | 2013 |
Regulation of DARPP‐32 dephosphorylation at PKA‐and Cdk5‐sites by NMDA and AMPA receptors: distinct roles of calcineurin and protein phosphatase‐2A A Nishi, JA Bibb, S Matsuyama, M Hamada, H Higashi, AC Nairn, ... Journal of neurochemistry 81 (4), 832-841, 2002 | 178 | 2002 |
Requirement for DARPP-32 in progesterone-facilitated sexual receptivity in female rats and mice SK Mani, AA Fienberg, JP O'Callaghan, GL Snyder, PB Allen, PK Dash, ... Science 287 (5455), 1053-1056, 2000 | 172 | 2000 |
The emerging role of Cdk5 in cancer K Pozo, JA Bibb Trends in cancer 2 (10), 606-618, 2016 | 169 | 2016 |
Roscovitine: a novel regulator of P/Q‐type calcium channels and transmitter release in central neurons Z Yan, P Chi, J A. Bibb, T A. Ryan, P Greengard The Journal of physiology 540 (3), 761-770, 2002 | 162 | 2002 |
Regulation of cyclin-dependent kinase 5 and casein kinase 1 by metabotropic glutamate receptors F Liu, XH Ma, J Ule, JA Bibb, A Nishi, AJ DeMaggio, Z Yan, AC Nairn, ... Proceedings of the National Academy of Sciences 98 (20), 11062-11068, 2001 | 150 | 2001 |
Cdk5 is essential for adult hippocampal neurogenesis DC Lagace, DR Benavides, JW Kansy, M Mapelli, P Greengard, JA Bibb, ... Proceedings of the National Academy of Sciences 105 (47), 18567-18571, 2008 | 146 | 2008 |
Memory enhancement by targeting Cdk5 regulation of NR2B F Plattner, A Hernández, TM Kistler, K Pozo, P Zhong, EY Yuen, C Tan, ... Neuron 81 (5), 1070-1083, 2014 | 143 | 2014 |