Advances in generating functional diversity for directed protein evolution AV Shivange, J Marienhagen, H Mundhada, A Schenk, U Schwaneberg Current Opinion in Chemical Biology 13 (1), 19-25, 2009 | 216 | 2009 |
Directed evolution of a selective and sensitive serotonin biosensor via machine learning E Unger, JP Keller, M Altermatt, R Liang, Z Yao, J Sun, A Matsui, C Dong, ... Cell 183 (7), 1986-2002, 2019 | 151 | 2019 |
OmniChange: the sequence independent method for simultaneous site-saturation of five codons A Dennig, AV Shivange, J Marienhagen, U Schwaneberg PloS one 6 (10), e26222, 2011 | 131 | 2011 |
Directed evolution of a highly active Yersinia mollaretii phytase AV Shivange, A Serwe, A Dennig, D Roccatano, S Haefner, ... Applied microbiology and biotechnology 95, 405-418, 2012 | 95 | 2012 |
A fast genetically encoded fluorescent sensor for faithful in vivo acetylcholine detection in mice, fish, worms and flies PM Borden, P Zhang, AV Shivange, JS Marvin, J Cichon, C Dan, ... BioRxiv, 2020.02. 07.939504, 2020 | 81 | 2020 |
Nicotinamide inhibits Plasmodium falciparum Sir2 activity in vitro and parasite growth D Prusty, P Mehra, S Srivastava, AV Shivange, A Gupta, N Roy, SK Dhar FEMS microbiology letters 282 (2), 266-272, 2008 | 75 | 2008 |
Multi-site saturation by OmniChange yields a pH-and thermally improved phytase AV Shivange, A Dennig, U Schwaneberg Journal of biotechnology 170, 68-72, 2014 | 62 | 2014 |
Extending the substrate scope of a Baeyer–Villiger monooxygenase by multiple-site mutagenesis HM Dudek, MJ Fink, AV Shivange, A Dennig, MD Mihovilovic, ... Applied microbiology and biotechnology 98, 4009-4020, 2014 | 55 | 2014 |
Determining the pharmacokinetics of nicotinic drugs in the endoplasmic reticulum using biosensors AV Shivange, PM Borden, AK Muthusamy, AL Nichols, K Bera, H Bao, ... The Journal of general physiology 151 (6), 738, 2019 | 54 | 2019 |
Design of an activity and stability improved carbonyl reductase from Candida parapsilosis A Jakoblinnert, A van den Wittenboer, AV Shivange, M Bocola, L Heffele, ... Journal of biotechnology 165 (1), 52-62, 2013 | 43 | 2013 |
P-LinK: A method for generating multicomponent cytochrome P450 fusions with variable linker length KD Belsare, AJ Ruff, R Martinez, AV Shivange, H Mundhada, D Holtmann, ... Biotechniques 57 (1), 13-20, 2014 | 40 | 2014 |
Iterative key-residues interrogation of a phytase with thermostability increasing substitutions identified in directed evolution AV Shivange, D Roccatano, U Schwaneberg Applied microbiology and biotechnology 100, 227-242, 2016 | 36 | 2016 |
Reengineered carbonyl reductase for reducing methyl-substituted cyclohexanones A Jakoblinnert, J Wachtmeister, L Schukur, AV Shivange, M Bocola, ... Protein Engineering, Design & Selection 26 (4), 291-298, 2013 | 34 | 2013 |
Recent advances in directed phytase evolution and rational phytase engineering AV Shivange, U Schwaneberg Directed Enzyme Evolution: Advances and Applications, 145-172, 2017 | 25 | 2017 |
Protein consensus-based surface engineering (ProCoS): a computer-assisted method for directed protein evolution AV Shivange, HW Hoeffken, S Haefner, U Schwaneberg BioTechniques 61 (6), 305-314, 2016 | 24 | 2016 |
Conformational dynamics of active site loop in Escherichia coli phytase AV Shivange, U Schwaneberg, D Roccatano Biopolymers 93 (11), 994-1002, 2010 | 24 | 2010 |
Fluorescence activation mechanism and imaging of drug permeation with new sensors for smoking-cessation ligands AL Nichols, Z Blumenfeld, C Fan, L Luebbert, AEM Blom, BN Cohen, ... Elife 11, e74648, 2022 | 20 | 2022 |
dRTP and dPTP a complementary nucleotide couple for the Sequence Saturation Mutagenesis (SeSaM) method AJ Ruff, J Marienhagen, R Verma, D Roccatano, HG Genieser, ... Journal of Molecular Catalysis B: Enzymatic 84, 40-47, 2012 | 19 | 2012 |
Structural analysis of trypanosomal sirtuin: an insight for selective drug design S Kaur, AV Shivange, N Roy Molecular diversity 14, 169-178, 2010 | 17 | 2010 |
Biosensors show the pharmacokinetics of S-ketamine in the endoplasmic reticulum K Bera, A Kamajaya, AV Shivange, AK Muthusamy, AL Nichols, ... Frontiers in cellular neuroscience 13, 499, 2019 | 13 | 2019 |