The NASA Twins Study: A multidimensional analysis of a year-long human spaceflight FE Garrett-Bakelman, M Darshi, SJ Green, RC Gur, L Lin, BR Macias, ... Science 364 (6436), eaau8650, 2019 | 881 | 2019 |
Metabolic effects of intermittent fasting RE Patterson, DD Sears Annual review of nutrition 37 (1), 371-393, 2017 | 858 | 2017 |
Intermittent fasting and human metabolic health RE Patterson, GA Laughlin, DD Sears, AZ LaCroix, C Marinac, LC Gallo, ... Journal of the Academy of Nutrition and Dietetics 115 (8), 1203, 2015 | 515 | 2015 |
Toll-like receptor 4–dependent and–independent cytokine secretion induced by minimally oxidized low-density lipoprotein in macrophages YI Miller, S Viriyakosol, DS Worrall, A Boullier, S Butler, JL Witztum Arteriosclerosis, thrombosis, and vascular biology 25 (6), 1213-1219, 2005 | 364 | 2005 |
SirT1 regulates adipose tissue inflammation MP Gillum, ME Kotas, DM Erion, R Kursawe, P Chatterjee, KT Nead, ... Diabetes 60 (12), 3235-3245, 2011 | 337 | 2011 |
PPARγ activation in adipocytes is sufficient for systemic insulin sensitization S Sugii, P Olson, DD Sears, M Saberi, AR Atkins, GD Barish, SH Hong, ... Proceedings of the National Academy of Sciences 106 (52), 22504-22509, 2009 | 312 | 2009 |
TLR4 and insulin resistance JJ Kim, DD Sears Gastroenterology research and practice 2010 (1), 212563, 2010 | 311 | 2010 |
Adipocyte NCoR knockout decreases PPARγ phosphorylation and enhances PPARγ activity and insulin sensitivity P Li, WQ Fan, J Xu, M Lu, H Yamamoto, J Auwerx, DD Sears, S Talukdar, ... Cell 147 (4), 815-826, 2011 | 303 | 2011 |
Hematopoietic-Derived Galectin-3 Causes Cellular and Systemic Insulin Resistance P Li, S Liu, M Lu, G Bandyopadhyay, D Oh, T Imamura, AMF Johnson, ... Cell 167 (4), 973-984. e12, 2016 | 289 | 2016 |
Functional heterogeneity of CD11c-positive adipose tissue macrophages in diet-induced obese mice P Li, M Lu, MTA Nguyen, EJ Bae, J Chapman, D Feng, M Hawkins, ... Journal of biological chemistry 285 (20), 15333-15345, 2010 | 276 | 2010 |
Fatty acid-induced insulin resistance: decreased muscle PI3K activation but unchanged Akt phosphorylation YT Kruszynska, DS Worrall, J Ofrecio, JP Frias, G Macaraeg, JM Olefsky The Journal of Clinical Endocrinology & Metabolism 87 (1), 226-234, 2002 | 225 | 2002 |
Prolonged nightly fasting and breast cancer prognosis CR Marinac, SH Nelson, CI Breen, SJ Hartman, L Natarajan, JP Pierce, ... JAMA oncology 2 (8), 1049-1055, 2016 | 203 | 2016 |
Mechanisms of human insulin resistance and thiazolidinedione-mediated insulin sensitization DD Sears, G Hsiao, A Hsiao, JG Yu, CH Courtney, JM Ofrecio, ... Proceedings of the National Academy of Sciences 106 (44), 18745-18750, 2009 | 188 | 2009 |
TAK1-mediated autophagy and fatty acid oxidation prevent hepatosteatosis and tumorigenesis S Inokuchi-Shimizu, EJ Park, YS Roh, L Yang, B Zhang, J Song, S Liang, ... The Journal of clinical investigation 124 (8), 3566-3578, 2014 | 180 | 2014 |
Randomized controlled trial of increasing physical activity on objectively measured and self‐reported cognitive functioning among breast cancer survivors: The memory & motion study SJ Hartman, SH Nelson, E Myers, L Natarajan, DD Sears, BW Palmer, ... Cancer 124 (1), 192-202, 2018 | 168 | 2018 |
FOXO1 transrepresses peroxisome proliferator-activated receptor γ transactivation, coordinating an insulin-induced feed-forward response in adipocytes WQ Fan, T Imamura, N Sonoda, DD Sears, D Patsouris, JJ Kim, ... Journal of Biological Chemistry 284 (18), 12188-12197, 2009 | 160 | 2009 |
12/15-lipoxygenase is required for the early onset of high fat diet-induced adipose tissue inflammation and insulin resistance in mice DD Sears, PD Miles, J Chapman, JM Ofrecio, F Almazan, D Thapar, ... PLoS One 4 (9), e7250, 2009 | 156 | 2009 |
Circulating adipocyte-derived extracellular vesicles are novel markers of metabolic stress A Eguchi, M Lazic, AM Armando, SA Phillips, R Katebian, S Maraka, ... Journal of molecular medicine 94, 1241-1253, 2016 | 147 | 2016 |
Time-restricted feeding improves insulin resistance and hepatic steatosis in a mouse model of postmenopausal obesity H Chung, W Chou, DD Sears, RE Patterson, NJG Webster, LG Ellies Metabolism 65 (12), 1743-1754, 2016 | 145 | 2016 |
Frequency and Circadian Timing of Eating May Influence Biomarkers of Inflammation and Insulin Resistance Associated with Breast Cancer Risk CR Marinac, DD Sears, L Natarajan, LC Gallo, CI Breen, RE Patterson PloS one 10 (8), e0136240, 2015 | 137 | 2015 |