| The Bacterial Genomic Context of Highly Trimethoprim-Resistant DfrB Dihydrofolate Reductases Highlights An Emerging Threat to Public Health C Lemay-St-Denis, SS Diwan, JN Pelletier Antibiotics 10 (4), 433, 2021 | 15 | 2021 |
| Dual-target inhibitors of the folate pathway inhibit intrinsically trimethoprim-resistant DfrB dihydrofolate reductases JL Toulouse, G Shi, C Lemay-St-Denis, MC Ebert, D Deon, M Gagnon, ... ACS Medicinal Chemistry Letters 11 (11), 2261-2267, 2020 | 13 | 2020 |
| Tuning selectivity in CalA lipase: beyond tunnel engineering L Alejaldre, C Lemay-St-Denis, JN Pelletier, D Quaglia Biochemistry 62 (2), 396-409, 2022 | 11 | 2022 |
| Trimethoprim resistance in surface and wastewater is mediated by contrasting variants of the dfrB gene D Kneis, C Lemay-St-Denis, S Cellier-Goetghebeur, AX Elena, ... The ISME Journal 17 (9), 1455-1466, 2023 | 7 | 2023 |
| Integrating dynamics into enzyme engineering C Lemay-St-Denis, N Doucet, JN Pelletier Protein Engineering, Design and Selection 35, gzac015, 2022 | 7 | 2022 |
| A conserved SH3-like fold in diverse putative proteins tetramerizes into an oxidoreductase providing an antimicrobial resistance phenotype C Lemay-St-Denis, L Alejaldre, Z Jemouai, K Lafontaine, M St-Aubin, ... Philosophical Transactions of the Royal Society B 378 (1871), 20220040, 2023 | 6 | 2023 |
| Development of sulfahydantoin derivatives as β-lactamase inhibitors PA Paquet-Côté, L Alejaldre, CL Verreault, SMC Gobeil, R Lamoureux, ... Bioorganic & Medicinal Chemistry Letters, 127781, 2021 | 6 | 2021 |
| Computational identification of a multi-peptide vaccine candidate in E2 glycoprotein against diverse hepatitis c virus genotypes S Kumari, A Kessel, D Singhal, G Kaur, D Bern, C Lemay-St-Denis, ... Journal of Biomolecular Structure and Dynamics 41 (20), 11044-11061, 2023 | 4 | 2023 |
| Discovery of Highly Trimethoprim-Resistant DfrB Dihydrofolate Reductases in Diverse Environmental Settings Suggests an Evolutionary Advantage Unrelated to Antibiotic Resistance S Cellier-Goetghebeur, K Lafontaine, C Lemay-St-Denis, P Tsamo, ... Antibiotics 11 (12), 1768, 2022 | 4 | 2022 |
| Known evolutionary paths are accessible to engineered ß-lactamases having altered protein motions at the timescale of catalytic turnover L Alejaldre, C Lemay-St-Denis, CP Lopez, FS Jodar, V Guallar, ... Frontiers in molecular biosciences 7, 2020 | 3 | 2020 |
| From a binding module to essential catalytic activity: how nature stumbled on a good thing C Lemay-St-Denis, JN Pelletier Chemical Communications 59 (84), 12560-12572, 2023 | 2 | 2023 |
| Indigo Formation as a Predictor of Substrate Promiscuity in Cytochrome P450 BM3 Libraries D Valikhani, JN Besna, O Rousseau, C Lemay-St-Denis, G Lamoureux, ... | | 2024 |
| Tirer profit de l’espace de séquence: une approche multidisciplinaire pour élucider l’évolution d’une famille d’enzymes primitives C Lemay-St-Denis | | 2024 |
Joelle N PelletierUniversité de Montréal在 umontreal.ca 的电子邮件经过验证
