Somatic mosaic IDH1 and IDH2 mutations are associated with enchondroma and spindle cell hemangioma in Ollier disease and Maffucci syndrome TC Pansuriya, R van Eijk, P d'Adamo, MAJH van Ruler, ML Kuijjer, ... Nature genetics 43 (12), 1256-1261, 2011 | 580 | 2011 |
Restoration of chemosensitivity for doxorubicin and cisplatin in chondrosarcoma in vitro: BCL-2 family members cause chemoresistance JG Van Oosterwijk, B Herpers, D Meijer, IH Briaire-de Bruijn, ... Annals of oncology 23 (6), 1617-1626, 2012 | 150 | 2012 |
Duplications of noncoding elements 5′ of SOX9 are associated with brachydactyly-anonychia I Kurth, E Klopocki, S Stricker, J van Oosterwijk, S Vanek, J Altmann, ... Nature genetics 41 (8), 862-863, 2009 | 135 | 2009 |
Kinome profiling of chondrosarcoma reveals SRC-pathway activity and dasatinib as option for treatment YM Schrage, IH Briaire-de Bruijn, NFCC de Miranda, J van Oosterwijk, ... Cancer Research 69 (15), 6216-6222, 2009 | 121 | 2009 |
Update on targets and novel treatment options for high-grade osteosarcoma and chondrosarcoma JG van Oosterwijk, JK Anninga, H Gelderblom, AM Cleton-Jansen, ... Hematology/Oncology Clinics 27 (5), 1021-1048, 2013 | 96 | 2013 |
Functional profiling of receptor tyrosine kinases and downstream signaling in human chondrosarcomas identifies pathways for rational targeted therapy YX Zhang, JG van Oosterwijk, E Sicinska, S Moss, SP Remillard, ... Clinical Cancer Research 19 (14), 3796-3807, 2013 | 94 | 2013 |
Src kinases in chondrosarcoma chemoresistance and migration: dasatinib sensitises to doxorubicin in TP53 mutant cells JG Van Oosterwijk, M Van Ruler, IH Briaire-de Bruijn, B Herpers, ... British journal of cancer 109 (5), 1214-1222, 2013 | 80 | 2013 |
Screening for potential targets for therapy in mesenchymal, clear cell, and dedifferentiated chondrosarcoma reveals Bcl-2 family members and TGFβ as potential targets JG van Oosterwijk, D Meijer, MAJH van Ruler, BEWM van den Akker, ... The American journal of pathology 182 (4), 1347-1356, 2013 | 71 | 2013 |
Bcl-xl as the most promising Bcl-2 family member in targeted treatment of chondrosarcoma Y de Jong, D Monderer, E Brandinelli, M Monchanin, BE van den Akker, ... Oncogenesis 7 (9), 74, 2018 | 61 | 2018 |
Three new chondrosarcoma cell lines: one grade III conventional central chondrosarcoma and two dedifferentiated chondrosarcomas of bone JG van Oosterwijk, D de Jong, MAJH van Ruler, PCW Hogendoorn, ... BMC cancer 12, 1-10, 2012 | 51 | 2012 |
Targeting survivin as a potential new treatment for chondrosarcoma of bone Y De Jong, JG Van Oosterwijk, AB Kruisselbrink, IH Briaire-de Bruijn, ... Oncogenesis 5 (5), e222-e222, 2016 | 47 | 2016 |
Hypoxia-induced upregulation of BMX kinase mediates therapeutic resistance in acute myeloid leukemia JG Van Oosterwijk, DR Buelow, CD Drenberg, A Vasilyeva, L Li, L Shi, ... The Journal of Clinical Investigation 128 (1), 369-380, 2018 | 40 | 2018 |
Cartilage tumour progression is characterized by an increased expression of heparan sulphate 6O-sulphation-modifying enzymes CJF Waaijer, CE de Andrea, A Hamilton, JG van Oosterwijk, SE Stringer, ... Virchows Archiv 461, 475-481, 2012 | 32 | 2012 |
Resistance to ticks and the path to anti-tick and transmission blocking vaccines JG van Oosterwijk, SK Wikel Vaccines 9 (7), 725, 2021 | 31 | 2021 |
Oral Delivery of Bacillus subtilis Expressing Chicken NK-2 Peptide Protects Against Eimeria acervulina Infection in Broiler Chickens SS Wickramasuriya, I Park, Y Lee, WH Kim, C Przybyszewski, CG Gay, ... Frontiers in Veterinary Science 8, 684818, 2021 | 29 | 2021 |
Field evaluation of a novel oral reservoir-targeted vaccine against Borrelia burgdorferi utilizing an inactivated whole-cell bacterial antigen expression vehicle KC Stafford, SC Williams, JG van Oosterwijk, MA Linske, S Zatechka, ... Experimental and Applied Acarology 80, 257-268, 2020 | 22 | 2020 |
Anti‐tick and pathogen transmission blocking vaccines JG van Oosterwijk Parasite Immunology 43 (5), e12831, 2021 | 16 | 2021 |
Small mitochondrial Arf (smArf) protein corrects p53-independent developmental defects of Arf tumor suppressor-deficient mice JG van Oosterwijk, C Li, X Yang, JT Opferman, CJ Sherr Proceedings of the National Academy of Sciences 114 (28), 7420-7425, 2017 | 16 | 2017 |
An orthotopic mouse model for chondrosarcoma of bone provides an in vivo tool for drug testing JG van Oosterwijk, JRM Plass, D Meijer, I Que, M Karperien, JVMG Bovée Virchows Archiv 466, 101-109, 2015 | 13 | 2015 |
Orally delivered Bacillus subtilis expressing chicken NK-2 peptide stabilizes gut microbiota and enhances intestinal health and local immunity in coccidiosis-infected broiler … SS Wickramasuriya, I Park, Y Lee, LM Richer, C Przybyszewski, CG Gay, ... Poultry Science 102 (5), 102590, 2023 | 11 | 2023 |