A practical guide to single-cell RNA-sequencing for biomedical research and clinical applications A Haque, J Engel, SA Teichmann, T Lönnberg Genome medicine 9, 1-12, 2017 | 972 | 2017 |
T cell fate and clonality inference from single-cell transcriptomes MJT Stubbington, T Lönnberg, V Proserpio, S Clare, AO Speak, ... Nature methods 13 (4), 329-332, 2016 | 451 | 2016 |
Microanatomy of the human atherosclerotic plaque by single-cell transcriptomics MAC Depuydt, KHM Prange, L Slenders, T Örd, D Elbersen, A Boltjes, ... Circulation research 127 (11), 1437-1455, 2020 | 357 | 2020 |
Single-cell RNA-seq and computational analysis using temporal mixture modeling resolves TH1/TFH fate bifurcation in malaria T Lönnberg, V Svensson, KR James, D Fernandez-Ruiz, I Sebina, ... Science immunology 2 (9), eaal2192, 2017 | 284 | 2017 |
Single-cell survey of human lymphatics unveils marked endothelial cell heterogeneity and mechanisms of homing for neutrophils A Takeda, M Hollmén, D Dermadi, J Pan, KF Brulois, R Kaukonen, ... Immunity 51 (3), 561-572. e5, 2019 | 161 | 2019 |
Global chromatin state analysis reveals lineage-specific enhancers during the initiation of human T helper 1 and T helper 2 cell polarization RD Hawkins, A Larjo, SK Tripathi, U Wagner, Y Luu, T Lönnberg, ... Immunity 38 (6), 1271-1284, 2013 | 109 | 2013 |
Single‐cell technologies are revolutionizing the approach to rare cells V Proserpio, T Lönnberg Immunology and cell biology 94 (3), 225-229, 2016 | 93 | 2016 |
Single-cell epigenomics and functional fine-mapping of atherosclerosis GWAS loci T Örd, K Õunap, LK Stolze, R Aherrahrou, V Nurminen, A Toropainen, ... Circulation research 129 (2), 240-258, 2021 | 72 | 2021 |
Single-cell analysis of CD4+ T-cell differentiation reveals three major cell states and progressive acceleration of proliferation V Proserpio, A Piccolo, L Haim-Vilmovsky, G Kar, T Lönnberg, ... Genome biology 17, 1-15, 2016 | 69 | 2016 |
Quantitative proteomics analysis of the nuclear fraction of human CD4+ cells in the early phases of IL-4-induced Th2 differentiation R Moulder, T Lönnberg, LL Elo, JJ Filen, E Rainio, G Corthals, M Oresic, ... Molecular & Cellular Proteomics 9 (9), 1937-1953, 2010 | 59 | 2010 |
Early detection of peripheral blood cell signature in children developing β-cell autoimmunity at a young age H Kallionpää, J Somani, S Tuomela, U Ullah, R De Albuquerque, ... Diabetes 68 (10), 2024-2034, 2019 | 50 | 2019 |
Single-cell RNA-sequencing resolves self-antigen expression during mTEC development RJ Miragaia, X Zhang, T Gomes, V Svensson, T Ilicic, J Henriksson, G Kar, ... Scientific reports 8 (1), 685, 2018 | 49 | 2018 |
Transcriptome dynamics of CD4+ T cells during malaria maps gradual transit from effector to memory MSF Soon, HJ Lee, JA Engel, J Straube, BS Thomas, CPS Pernold, ... Nature Immunology 21 (12), 1597-1610, 2020 | 47 | 2020 |
An integrative computational systems biology approach identifies differentially regulated dynamic transcriptome signatures which drive the initiation of human T helper cell … T Äijö, SM Edelman, T Lönnberg, A Larjo, H Kallionpää, S Tuomela, ... BMC genomics 13, 1-20, 2012 | 45 | 2012 |
Systemic blockade of clever-1 elicits lymphocyte activation alongside checkpoint molecule downregulation in patients with solid tumors: results from a phase I/II clinical trial R Virtakoivu, JH Rannikko, M Viitala, F Vaura, A Takeda, T Lönnberg, ... Clinical Cancer Research 27 (15), 4205-4220, 2021 | 36 | 2021 |
Global and targeted approaches to single-cell transcriptome characterization AA Kolodziejczyk, T Lönnberg Briefings in functional genomics 17 (4), 209-219, 2018 | 36 | 2018 |
Peripheral blood DNA methylation differences in twin pairs discordant for Alzheimer’s disease M Konki, M Malonzo, IK Karlsson, N Lindgren, B Ghimire, J Smolander, ... Clinical epigenetics 11, 1-12, 2019 | 32 | 2019 |
Single-cell characterization of anti–LAG-3 and anti–PD-1 combination treatment in patients with melanoma J Huuhtanen, H Kasanen, K Peltola, T Lönnberg, V Glumoff, O Brück, ... The Journal of Clinical Investigation 133 (6), 2023 | 31 | 2023 |
Single-cell characterization of leukemic and non-leukemic immune repertoires in CD8+ T-cell large granular lymphocytic leukemia J Huuhtanen, D Bhattacharya, T Lönnberg, M Kankainen, C Kerr, ... Nature Communications 13 (1), 1981, 2022 | 31 | 2022 |
Somatic mTOR mutation in clonally expanded T lymphocytes associated with chronic graft versus host disease D Kim, G Park, J Huuhtanen, S Lundgren, RK Khajuria, AM Hurtado, ... Nature communications 11 (1), 2246, 2020 | 28 | 2020 |