Ryanodine receptor oxidation causes intracellular calcium leak and muscle weakness in aging DC Andersson, MJ Betzenhauser, S Reiken, AC Meli, A Umanskaya, ... Cell metabolism 14 (2), 196-207, 2011 | 449 | 2011 |
Structure of the membrane protein FhaC: a member of the Omp85-TpsB transporter superfamily B Clantin, AS Delattre, P Rucktooa, N Saint, AC Méli, C Locht, ... Science 317 (5840), 957-961, 2007 | 322 | 2007 |
Role of chronic ryanodine receptor phosphorylation in heart failure and β-adrenergic receptor blockade in mice J Shan, MJ Betzenhauser, A Kushnir, S Reiken, AC Meli, A Wronska, ... The Journal of clinical investigation 120 (12), 4375-4387, 2010 | 279 | 2010 |
Role of leaky neuronal ryanodine receptors in stress-induced cognitive dysfunction X Liu, MJ Betzenhauser, S Reiken, AC Meli, W Xie, BX Chen, O Arancio, ... Cell 150 (5), 1055-1067, 2012 | 174 | 2012 |
Post-translational remodeling of ryanodine receptor induces calcium leak leading to Alzheimer’s disease-like pathologies and cognitive deficits A Lacampagne, X Liu, S Reiken, R Bussiere, AC Meli, I Lauritzen, ... Acta neuropathologica 134, 749-767, 2017 | 156 | 2017 |
Ryanodine receptor leak mediated by caspase-8 activation leads to left ventricular injury after myocardial ischemia-reperfusion J Fauconnier, AC Meli, J Thireau, S Roberge, J Shan, Y Sassi, SR Reiken, ... Proceedings of the National Academy of Sciences 108 (32), 13258-13263, 2011 | 132 | 2011 |
Leaky ryanodine receptors in β-sarcoglycan deficient mice: a potential common defect in muscular dystrophy DC Andersson, AC Meli, S Reiken, MJ Betzenhauser, A Umanskaya, ... Skeletal muscle 2, 1-9, 2012 | 94 | 2012 |
TNF-α-mediated caspase-8 activation induces ROS production and TRPM2 activation in adult ventricular myocytes S Roberge, J Roussel, DC Andersson, AC Meli, B Vidal, F Blandel, ... Cardiovascular research 103 (1), 90-99, 2014 | 82 | 2014 |
A novel ryanodine receptor mutation linked to sudden death increases sensitivity to cytosolic calcium AC Meli, MM Refaat, M Dura, S Reiken, A Wronska, J Wojciak, J Carroll, ... Circulation research 109 (3), 281-290, 2011 | 78 | 2011 |
Channel properties of TpsB transporter FhaC point to two functional domains with a C-terminal protein-conducting pore AC Méli, H Hodak, B Clantin, C Locht, G Molle, F Jacob-Dubuisson, ... Journal of Biological Chemistry 281 (1), 158-166, 2006 | 71 | 2006 |
Atomic force microscopy combined with human pluripotent stem cell derived cardiomyocytes for biomechanical sensing M Pesl, J Pribyl, I Acimovic, A Vilotic, S Jelinkova, A Salykin, ... Biosensors and Bioelectronics 85, 751-757, 2016 | 70 | 2016 |
Human pluripotent stem cell‐derived cardiomyocytes as research and therapeutic tools I Acimovic, A Vilotic, M Pesl, A Lacampagne, P Dvorak, V Rotrekl, AC Meli BioMed research international 2014 (1), 512831, 2014 | 69 | 2014 |
Forced aggregation and defined factors allow highly uniform-sized embryoid bodies and functional cardiomyocytes from human embryonic and induced pluripotent stem cells M Pesl, I Acimovic, J Pribyl, R Hezova, A Vilotic, J Fauconnier, J Vrbsky, ... Heart and vessels 29, 834-846, 2014 | 60 | 2014 |
Speckle-tracking echocardiography in children with Duchenne muscular dystrophy: a prospective multicenter controlled cross-sectional study P Amedro, M Vincenti, G De La Villeon, K Lavastre, C Barrea, ... Journal of the American Society of Echocardiography 32 (3), 412-422, 2019 | 54 | 2019 |
Post-translational modifications and diastolic calcium leak associated to the novel RyR2-D3638A mutation lead to CPVT in patient-specific hiPSC-derived cardiomyocytes I Acimovic, MM Refaat, A Moreau, A Salykin, S Reiken, Y Sleiman, ... Journal of clinical medicine 7 (11), 423, 2018 | 49 | 2018 |
MicroRNA profiling of activated and tolerogenic human dendritic cells Z Stumpfova, R Hezova, AC Meli, O Slaby, J Michalek Mediators of inflammation 2014 (1), 259689, 2014 | 49 | 2014 |
Short-coupled polymorphic ventricular tachycardia at rest linked to a novel ryanodine receptor (RyR2) mutation: leaky RyR2 channels under non-stress conditions JW Cheung, AC Meli, W Xie, S Mittal, S Reiken, A Wronska, L Xu, ... International journal of cardiology 180, 228-236, 2015 | 47 | 2015 |
Dystrophin deficiency leads to genomic instability in human pluripotent stem cells via NO synthase-induced oxidative stress S Jelinkova, P Fojtik, A Kohutova, A Vilotic, L Marková, M Pesl, T Jurakova, ... Cells 8 (1), 53, 2019 | 37 | 2019 |
DMD Pluripotent Stem Cell Derived Cardiac Cells Recapitulate in vitro Human Cardiac Pathophysiology S Jelinkova, A Vilotic, J Pribyl, F Aimond, A Salykin, I Acimovic, M Pesl, ... Frontiers in bioengineering and biotechnology 8, 535, 2020 | 26 | 2020 |
Modeling polymorphic ventricular tachycardia at rest using patient-specific induced pluripotent stem cell-derived cardiomyocytes Y Sleiman, M Souidi, R Kumar, E Yang, F Jaffré, T Zhou, A Bernardin, ... EBioMedicine 60, 2020 | 20 | 2020 |