p53 mRNA controls p53 activity by managing Mdm2 functions MM Candeias, L Malbert-Colas, DJ Powell, C Daskalogianni, MM Maslon, ... Nature cell biology 10 (9), 1098-1105, 2008 | 293 | 2008 |
The p53 mRNA-Mdm2 interaction controls Mdm2 nuclear trafficking and is required for p53 activation following DNA damage M Gajjar, MM Candeias, L Malbert-Colas, A Mazars, J Fujita, ... Cancer cell 21 (1), 25-35, 2012 | 189 | 2012 |
Endoplasmic reticulum stress induces G2 cell-cycle arrest via mRNA translation of the p53 isoform p53/47 K Bourougaa, N Naski, C Boularan, C Mlynarczyk, MM Candeias, ... Molecular cell 38 (1), 78-88, 2010 | 181 | 2010 |
Expression of p53 and p53/47 are controlled by alternative mechanisms of messenger RNA translation initiation MM Candeias, DJ Powell, E Roubalova, S Apcher, K Bourougaa, ... Oncogene 25 (52), 6936-6947, 2006 | 133 | 2006 |
Cancer‐specific mutations in p53 induce the translation of Δ160p53 promoting tumorigenesis MM Candeias, M Hagiwara, M Matsuda EMBO reports 17 (11), 1542-1551, 2016 | 70 | 2016 |
The p53 mrna-mdm2 interaction N Naski, M Gajjar, K Bourougaa, L Malbert-Colas, R Fåhraeus, ... Cell Cycle 8 (1), 31-34, 2009 | 70 | 2009 |
p53 and little brother p53/47: linking IRES activities with protein functions R Grover, MM Candeias, R Fåhraeus, S Das Oncogene 28 (30), 2766-2772, 2009 | 63 | 2009 |
Gly-Ala repeats induce position-and substrate-specific regulation of 26 S proteasome-dependent partial processing C Daskalogianni, S Apcher, MM Candeias, N Naski, F Calvo, R Fahraeus Journal of Biological Chemistry 283 (44), 30090-30100, 2008 | 62 | 2008 |
Stress-dependent changes in the properties of p53 complexes by the alternative translation product p53/47 DJ Powell, R Hrstka, M Candeias, K Bourougaa, B Vojteseka, R Fåhraeus Cell Cycle 7 (7), 950-959, 2008 | 62 | 2008 |
Identification of a novel enhancer that binds Sp1 and contributes to induction of cold-inducible RNA-binding protein (cirp) expression in mammalian cells Y Sumitomo, H Higashitsuji, H Higashitsuji, Y Liu, T Fujita, T Sakurai, ... BMC biotechnology 12, 1-9, 2012 | 50 | 2012 |
Cap-independent translation ensures mTOR expression and function upon protein synthesis inhibition A Marques-Ramos, MM Candeias, J Menezes, R Lacerda, M Willcocks, ... Rna 23 (11), 1712-1728, 2017 | 36 | 2017 |
Distinct expression patterns of the E3 ligase SIAH-1 and its partner Kid/KIF22 in normal tissues and in the breast tumoral processes H Bruzzoni-Giovanelli, P Fernandez, L Veiga, MP Podgorniak, DJ Powell, ... Journal of Experimental & Clinical Cancer Research 29, 1-10, 2010 | 33 | 2010 |
The novel platinum (IV) complex LA-12 induces p53 and p53/47 responses that differ from the related drug, cisplatin R Hrstka, DJ Powell, V Kvardova, E Roubalova, K Bourougaa, ... Anti-Cancer Drugs 19 (4), 369-379, 2008 | 25 | 2008 |
The can and can’t dos of p53 RNA MM Candeias Biochimie 93 (11), 1962-1965, 2011 | 24 | 2011 |
Glutamine deficiency in solid tumor cells confers resistance to ribosomal RNA synthesis inhibitors M Pan, C Zorbas, M Sugaya, K Ishiguro, M Kato, M Nishida, HF Zhang, ... Nature communications 13 (1), 3706, 2022 | 14 | 2022 |
Long noncoding RNA‐dependent methylation of nonhistone proteins S Jantrapirom, N Koonrungsesomboon, H Yoshida, M M. Candeias, ... Wiley Interdisciplinary Reviews: RNA 12 (6), e1661, 2021 | 14 | 2021 |
Alternative mechanisms of mRNA translation initiation in cellular stress response and cancer R Lacerda, J Menezes, MM Candeias The mRNA Metabolism in Human Disease, 117-132, 2019 | 12 | 2019 |
Conserved double translation initiation site for Δ160p53 protein Hints at Isoform’s Key role in mammalian Physiology MJ López-Iniesta, SN Parkar, AC Ramalho, R Lacerda, IF Costa, J Zhao, ... International Journal of Molecular Sciences 23 (24), 15844, 2022 | 5 | 2022 |
Mutant p53 loses “gain-of-functions” after losing isoform expression MM Candeias 6th International Mutant p53 Workshop, 1, 2013 | 2 | 2013 |
Δ246p53 is a new p53 isoform that responds to DNA damage and regulates tumour growth SN Parkar, MJ López-Iniesta, AC Ramalho, K Kimura, J Zhao, ... bioRxiv, 2023.04. 07.536059, 2023 | 1 | 2023 |