Guidelines for the use and interpretation of assays for monitoring autophagy DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13245* | 2021 |
ULK1· ATG13· FIP200 complex mediates mTOR signaling and is essential for autophagy IG Ganley, DH Lam, J Wang, X Ding, S Chen, X Jiang Journal of Biological Chemistry 284 (18), 12297-12305, 2009 | 1738* | 2009 |
The mammalian ULK1 complex and autophagy initiation M Zachari, IG Ganley Essays in biochemistry 61 (6), 585-596, 2017 | 692 | 2017 |
The ULK1 complex: sensing nutrient signals for autophagy activation PM Wong, C Puente, IG Ganley, X Jiang Autophagy 9 (2), 124-137, 2013 | 567 | 2013 |
Loss of iron triggers PINK1/Parkin‐independent mitophagy GFG Allen, R Toth, J James, IG Ganley EMBO reports 14 (12), 1127-1135, 2013 | 520 | 2013 |
Basal mitophagy occurs independently of PINK1 in mouse tissues of high metabolic demand TG McWilliams, AR Prescott, L Montava-Garriga, G Ball, F Singh, E Barini, ... Cell metabolism 27 (2), 439-449. e5, 2018 | 515 | 2018 |
mito-QC illuminates mitophagy and mitochondrial architecture in vivo TG McWilliams, AR Prescott, GFG Allen, J Tamjar, MJ Munson, ... Journal of Cell Biology 214 (3), 333-345, 2016 | 443 | 2016 |
Distinct autophagosomal-lysosomal fusion mechanism revealed by thapsigargin-induced autophagy arrest IG Ganley, PM Wong, N Gammoh, X Jiang Molecular cell 42 (6), 731-743, 2011 | 438 | 2011 |
Pharmacological inhibition of ULK1 kinase blocks mammalian target of rapamycin (mTOR)-dependent autophagy KJ Petherick, OJL Conway, C Mpamhanga, SA Osborne, A Kamal, ... Journal of Biological Chemistry 290 (18), 11376-11383, 2015 | 402 | 2015 |
Characterization of VPS34-IN1, a selective inhibitor of Vps34, reveals that the phosphatidylinositol 3-phosphate-binding SGK3 protein kinase is a downstream target of class III … R Bago, N Malik, MJ Munson, AR Prescott, P Davies, E Sommer, N Shpiro, ... Biochemical Journal 463 (3), 413-427, 2014 | 300 | 2014 |
Role of autophagy in histone deacetylase inhibitor-induced apoptotic and nonapoptotic cell death N Gammoh, D Lam, C Puente, I Ganley, PA Marks, X Jiang Proceedings of the National Academy of Sciences 109 (17), 6561-6565, 2012 | 238 | 2012 |
Rab9 GTPase regulates late endosome size and requires effector interaction for its stability IG Ganley, K Carroll, L Bittova, S Pfeffer Molecular biology of the cell 15 (12), 5420-5430, 2004 | 213 | 2004 |
A syntaxin 10–SNARE complex distinguishes two distinct transport routes from endosomes to the trans-Golgi in human cells IG Ganley, E Espinosa, SR Pfeffer The Journal of cell biology 180 (1), 159-172, 2008 | 197 | 2008 |
Clearance of damaged mitochondria via mitophagy is important to the protective effect of ischemic preconditioning in kidneys MJ Livingston, J Wang, J Zhou, G Wu, IG Ganley, JA Hill, XM Yin, Z Dong Autophagy 15 (12), 2142-2162, 2019 | 189 | 2019 |
mTOR activates the VPS 34–UVRAG complex to regulate autolysosomal tubulation and cell survival MJ Munson, GFG Allen, R Toth, DG Campbell, JM Lucocq, IG Ganley The EMBO journal 34 (17), 2272-2290, 2015 | 175 | 2015 |
LRRK2 is a negative regulator of Mycobacterium tuberculosis phagosome maturation in macrophages A Härtlova, S Herbst, J Peltier, A Rodgers, O Bilkei‐Gorzo, A Fearns, ... The EMBO journal 37 (12), e98694, 2018 | 172 | 2018 |
Outstanding questions in mitophagy: what we do and do not know L Montava-Garriga, IG Ganley Journal of molecular biology 432 (1), 206-230, 2020 | 170 | 2020 |
MTOR, PIK3C3, and autophagy: Signaling the beginning from the end MJ Munson, IG Ganley Autophagy 11 (12), 2375-2376, 2015 | 164 | 2015 |
Cholesterol accumulation sequesters Rab9 and disrupts late endosome function in NPC1-deficient cells IG Ganley, SR Pfeffer Journal of Biological Chemistry 281 (26), 17890-17899, 2006 | 160 | 2006 |
Clues to neuro-degeneration in Niemann-Pick type C disease from global gene expression profiling JV Reddy, IG Ganley, SR Pfeffer PloS one 1 (1), e19, 2006 | 150 | 2006 |